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991.
992.
Christopher E. Doughty Gregory R. Goldsmith Nicolas Raab Cecile A. J. Girardin Filio Farfan‐Amezquita Walter Huaraca‐Huasco Javier E. Silva‐Espejo Alejandro Araujo‐Murakami Antonio C. L. da Costa Wanderley Rocha David Galbraith Patrick Meir Dan B. Metcalfe Yadvinder Malhi 《Biotropica》2018,50(1):16-25
Why do some forests produce biomass more efficiently than others? Variations in Carbon Use Efficiency (CUE: total Net Primary Production (NPP)/ Gross Primary Production (GPP)) may be due to changes in wood residence time (Biomass/NPPwood), temperature, or soil nutrient status. We tested these hypotheses in 14, one ha plots across Amazonian and Andean forests where we measured most key components of net primary production (NPP: wood, fine roots, and leaves) and autotrophic respiration (Ra; wood, rhizosphere, and leaf respiration). We found that lower fertility sites were less efficient at producing biomass and had higher rhizosphere respiration, indicating increased carbon allocation to belowground components. We then compared wood respiration to wood growth and rhizosphere respiration to fine root growth and found that forests with residence times <40 yrs had significantly lower maintenance respiration for both wood and fine roots than forests with residence times >40 yrs. A comparison of rhizosphere respiration to fine root growth showed that rhizosphere growth respiration was significantly greater at low fertility sites. Overall, we found that Amazonian forests produce biomass less efficiently in stands with residence times >40 yrs and in stands with lower fertility, but changes to long‐term mean annual temperatures do not impact CUE. 相似文献
993.
994.
Primary familial brain calcification with a novel SLC20A2 mutation: Analysis of PiT‐2 expression and localization
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995.
Francisco Gerson Araújo Tatiana Pires Teixeira Ana Paula Penha Guedes Márcia Cristina Costa de Azevedo André Luiz Machado Pessanha 《Hydrobiologia》2018,817(1):205-213
Myriophyllum aquaticum is a semi-submerged exotic macrophyte that was introduced to China for many years. This species may be found in an emergent form in aquatic environments or in an amphibious form under drained conditions. Nuisance growth of this species has often been attributed to excessive amounts of nutrients. Therefore, we tested the following hypotheses: (1) high nutrient availability facilitates the establishment of M. aquaticum and (2) fragment type interacts with nutrient availability to determine the colonization and regeneration capacities of M. aquaticum. Two types of fragments were grown in water solutions with two levels of phosphorous. After 3 weeks, the survival rates showed no significant difference between the phosphorous treatments. However, emergent fragments showed higher RGR in the low and high phosphorous treatments than amphibious fragments. In addition, emergent fragments also showed higher regeneration capacities, indicating higher invasiveness in emergent fragments compared to amphibious fragments. Moreover, the high phosphorous concentration caused emergent fragments to produce more branches, indicating that nutrient availability may increase M. aquaticum propagule pressure. Our study highlights that nutrient supply increased emergent fragment establishment and shaped the invasion dynamics of macrophytes, which could help predict the spread and potential impact of exotic macrophytes in natural aquatic ecosystems. 相似文献
996.
Gax suppresses chemerin/CMKLR1‐induced preadipocyte biofunctions through the inhibition of Akt/mTOR and ERK signaling pathways
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Yunqi Jiang MD Ping Liu MD PhD Wenlin Jiao MD Juan Meng MD Jinbo Feng MD 《Journal of cellular physiology》2018,233(1):572-586
Adipose tissue is closely associated with angiogenesis and vascular remodeling. Chemerin is involved in inflammatory reaction and vascular dysfunction. However, the mechanisms of chemerin participating in vascular remodeling and whether Growth arrest‐specific homeobox (Gax) can effectively intervene it remain obscured. Here, 3T3‐F442A preadipocytes were cultured, injected into athymic mice to model fat pads, and treated respectively with Ad‐chemerin, Ad‐Gax, or specific inhibitors in vitro and in vivo. MTT, flow cytometry, Western blotting, and imunohisto(cyto)‐chemistry analyses showed that chemerin enhanced the expression of FABP4 and VEGF, activated Akt/mTOR and ERK pathways, increased the cell percent of S phase, decreased the percent of G0‐G1 phase and apoptotic cells, and augmented neovascular density in fat pads. Inversely, Gax suppressed the expression of these adipogenic and vasifactive markers and these signaling proteins, decreased the percent of S phase cells, and increased those of G0‐G1 phase and apoptotic cells, and reduced the neovascular density. Our results indicate that chemerin‐CMKLR1 activates Akt/mTOR and ERK pathways and facilitates preadipocyte proliferation, adipogenesis, and angiogenesis. Contrarily, Gax weakens the effect of chemerin on preadipocyte biofunctions. 相似文献
997.
Fibroblast dynamics as an in vitro screening platform for anti‐fibrotic drugs in primary myelofibrosis
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Ciprian Tomuleasa MD PhD Sonia Selicean MD Grigore Gafencu MD Bobe Petrushev MD Laura Pop PhD Cristian Berce PhD Anca Jurj PhD Adrian Trifa MD PhD Ana‐Maria Rosu MD Sergiu Pasca MD Lorand Magdo MD Mihnea Zdrenghea MD PhD Delia Dima MD PhD Alina Tanase MD PhD Ioana Frinc MD Anca Bojan MD Ioana Berindan‐Neagoe PhD Gabriel Ghiaur MD PhD Stefan O. Ciurea MD 《Journal of cellular physiology》2018,233(1):422-433
Although the cause for bone marrow fibrosis in patients with myelofibrosis remains controversial, it has been hypothesized that it is caused by extensive fibroblast proliferation under the influence of cytokines generated by the malignant megakaryocytes. Moreover, there is no known drug therapy which could reverse the process. We studied the fibroblasts in a novel system using the hanging drop method, evaluated whether the fibroblasts obtain from patients are part of the malignant clone of not and, using this system, we screen a large library of FDA‐approved drugs to identify potential drugs candidates that might be useful in the treatment of this disease, specifically which would inhibit fibroblast proliferation and the development of bone marrow fibrosis. We have found that the BM fibroblasts are not part of the malignant clone, as previously suspected and two immunosuppressive medications—cyclosporine and mycophenolate mophetil, as most potent suppressors of the fibroblast collagen production thus potentially inhibitors of bone marrow fibrosis production in myelofibrosis. 相似文献
998.
Effect of flood pulses on the trophic ecology of four piscivorous fishes from the eastern Amazon
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Thiago A. P. Barbosa Daniela C. O. Rosa Bruno E. Soares Christophe H. A. Costa Maria C. Esposito Luciano F. A. Montag 《Journal of fish biology》2018,93(1):30-39
This study investigated the effect of hydrological periods on the feeding activity and trophic interactions of four piscivorous fishes from the middle Xingu River, Brazil: pike‐characid Boulengerella cuvieri, dogtooth characin Hydrolycus armatus, dogtooth characin Hydrolycus tatauaia and South American silver croaker Plagioscion squamosissimus. Repletion Index (IR%), Alimentary Index (IAi%) and food web properties were calculated for each species. A total of 825 specimens were collected. The IR showed changes in feeding intensity of B. cuvieri, H. armatus and H. tatauaia among hydrological periods. Flood pulse showed no influence on composition and importance of food items consumed. Trophic connections showed that connectivity ranged from 0.025 to 0.038. The highest number of trophic connections (75) occurred in the high‐water period, when 51 food items were recorded and the lowest number of trophic connections (43) occurred in receding water, with 31 food items. In all food webs, over 45% of food items were consumed by only one species (ultra‐peripheral items), which is common in piscivorous fishes. 相似文献
999.
1000.
Elisabete A. Santos Priscilla M.G. Costa Christian S.A. Silva-Torres 《Biocontrol Science and Technology》2016,26(9):1184-1196
Prey for predators can fluctuate in abundance and in quality over time requiring predator strategies to cope with food shortage. Coccinellinae are often associated with sap-sucking pests that exhibit high population unpredictability such as aphids and psyllids. Eriopis connexa (Germar) (Coleoptera: Coccinellidae) is a predator with potential for biological control, especially a well-studied population which is resistant to pyrethroids used to control insect defoliators. Both larvae and adult E. connexa were provided ad libitum prey and non-prey foods (pollen and honey water solution) at increasing intervals from 1 to 10 days. Neonate larvae of E. connexa required eating prey daily to develop into adults. However, non-prey food such as honey water solution did prolong larval and adult survival but neither fulfilled larval development nor adult reproduction. Honey water solution promoted 100% adult survival up to 25 days in the adult stage without prey with oviposition returning after daily feeding on prey. Females subjected to increased feeding intervals over four days reduced oviposition and lived longer, but 10-day feeding intervals correlated with risk to adult survival. These results indicate the importance of non-food sources in E. connexa maintenance and the ability of larvae and adult females to compensate for prey scarcity. 相似文献