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91.
Jacinto Benhadi‐Marín Jos A. Pereira Jos P. Sousa Snia A. P. Santos 《The Annals of applied biology》2019,175(2):202-214
Spiders are successful natural enemies of pests occurring throughout the different strata of an agroecosystem. The study of their functional responses can provide information related to the potential effectiveness of different species and guilds on reducing a pest population. However, multiple prey availability may change the functional response of a predator. In this study, the functional responses of three species of spiders in single‐prey and multiple‐prey experiments were modelled. The spider species Haplodrassus rufipes, Araniella cucurbitina and Synema globosum were chosen as being representatives of ground runners, orb‐weavers and ambushers, respectively. Three prey species were selected: a target prey, the Mediterranean fruit fly Ceratitis capitata and two alternate prey species, the flour moth Ephestia kuehniella and the house cricket Acheta domesticus. When the selected target prey C. capitata was supplied in the single‐prey experiments, the most and the least efficient spider species were H. rufipes and S. globosum, respectively. However, opposite results were obtained when alternative preys were supplied. Also, A. cucurbitina significantly changed its functional response with the presence of alternative prey species. Considering the prey preference during the multiple‐prey experiments, A. domesticus, used as representative of a heavy, long‐sized and highly motile prey, was avoided whereas C. capitata, the target pest used as representative of light, small‐sized and moderately motile prey was preferred by the three species of spiders. Ephestia kuehniella, used as representative of light, medium‐sized and low motile prey was occasionally consumed. Each guild could include efficient predators against pests according to its hunting strategies and the ecological exploited niches. Orb‐weavers could be efficient predators against flying pests; ambushers such as S. globosum could contribute to the reduction of the populations of flower‐visiting pests, whereas active ground hunters may also play an important role preying on pests that develop a part or all of its life cycle in the ground. However, further research on feeding behaviour such as prey switching is needed for a better understanding of the effectiveness of spiders as natural enemies. 相似文献
92.
Gilmar da Silva Nunes Thais Aparecida Vitoriano Dantas Mileny dos Santos de Souza Izabela Nunes do Nascimento Jacinto de Luna Batista Jos Bruno Malaquias 《Entomologia Experimentalis et Applicata》2019,167(6):544-552
The diamondback moth (DBM), Plutella xylostella (L.) (Lepidoptera: Plutellidae), is the main pest of brassica crops worldwide. The ringlegged earwig, Euborellia annulipes (Lucas) (Dermaptera: Anisolabididae), has been reported as a potential predator of lepidopteran larvae, including this pest, and may therefore be used for biological control. Knowledge about predator–prey interactions is important to establish pest management strategies. Therefore, the objective of this work was to evaluate the influence of the developmental stage (larva and pupa) and density of P. xylostella on the preference and functional response of E. annulipes adult females. We used choice and no‐choice tests to evaluate the foraging behavior and preference of E. annulipes on DBM life stages and varied prey density to assess the type of functional response of the ringlegged earwig. Larvae were preferred over pupae, and the predator’s functional response was type II for both prey stages. Our results report the potential of E. annulipes as a biocontrol agent of P. xylostella. Understanding their interactions may help in decision‐making and optimization of integrated management strategies. 相似文献
93.
Lagman Joann Sayegh Paula Lee Christina S. Sulon Sarah M. Jacinto Alec Z. Sok Vanessa Peng Natalie Alp Deniz Benovic Jeffrey L. So Christopher H. 《Molecular and cellular biochemistry》2019,453(1-2):103-110
Molecular and Cellular Biochemistry - The critical role of the intrarenal renin-angiotensin system (RAS) in the development of kidney disease has been well demonstrated in animal and cell-culture... 相似文献
94.
Roveratti Mirela Casonato Jacinto Jeferson Lucas Oliveira Douglas Bendito da Silva Rubens Alexandre Andraus Rodrigo Antonio Carvalho de Oliveira Erick Prado Ribeiro Alex Silva Aguiar Andreo Fernando 《Amino acids》2019,51(4):589-597
Amino Acids - β-Alanine supplementation has been shown to increase muscle carnosine levels and exercise performance. However, its effects on muscle recovery from resistance exercise (RE)... 相似文献
95.
The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction 总被引:3,自引:0,他引:3
Wu Z Wagner MA Zheng L Parks JS Shy JM Smith JD Gogonea V Hazen SL 《Nature structural & molecular biology》2007,14(9):861-868
The cardioprotective function of high-density lipoprotein (HDL) is largely attributed to its ability to facilitate transport of cholesterol from peripheral tissues to the liver. However, HDL may become dysfunctional through oxidative modification, impairing cellular cholesterol efflux. Here we report a refined molecular model of nascent discoidal HDL, determined using hydrogen-deuterium exchange mass spectrometry. The model reveals two apolipoprotein A1 (apoA1) molecules arranged in an antiparallel double-belt structure, with residues 159-180 of each apoA1 forming a protruding solvent-exposed loop. We further show that this loop, including Tyr166, a preferred target for site-specific oxidative modification within atheroma, directly interacts with and activates lecithin cholesterol acyl transferase. These studies identify previously uncharacterized structural features of apoA1 in discoidal HDL that are crucial for particle maturation, and elucidate a structural and molecular mechanism for generating a dysfunctional form of HDL in atherosclerosis. 相似文献
96.
Anahí Sanluis-Verdes Namibia Sanluis-Verdes María Jesús Manso-Revilla Antonio Manuel Castro-Castro Jorge Pombo-Otero María Fraga-Mariño Jacinto Sanchez-Ibañez Nieves Doménech María Esther Rendal-Vázquez 《Cell and tissue banking》2017,18(1):1-15
Regenerative medicine, based on the use of stem cells, scaffolds and growth factors, has the potential to be a good approach for restoring damaged tissues of the central nervous system. This study investigated the use of human amniotic mesenchymal stem cells (hAMSC), human amniotic epithelial stem cells (hAESC), and human Wharton’s jelly mesenchymal stem cells (hWJMSC) derived from human umbilical cord as a source of stem cells, and the potential of the human amniotic membrane (HAM) as a scaffold and/or source of growth factors to promote nerve regeneration. The hAMSC and hAESC obtained from HAM and the hWJMSC from umbilical cords were cultured in induction medium to obtain neural-like cells. The morphological differentiation of hAMSC, hAESC and hWJMSC into neural-like cells was evident after 4–5 days, when they acquired an elongated and multipolar shape, and at 21 days, when they expressed neural and glial markers. On other way, the HAM was completely decellularized without affecting the components of the basement membrane or the matrix. Subsequently, hAMSC, hAESC and hWJMSC differentiated into neural-like cells were seeded onto the decellularized HAM, maintaining their morphology. Finally, conditioned media from the HAM allowed proliferation of hAMSC, hAESC and hWJMSC differentiated to neural-like cells. Both HAM and umbilical cord are biomaterials with great potential for use in regenerative medicine for the treatment of neurodegenerative diseases. 相似文献
97.
MGMT hypermethylation: a prognostic foe, a predictive friend 总被引:2,自引:0,他引:2
Alkylation of DNA at the O(6)-position of guanine is one of the most critical events leading to mutation, cancer, and cell death. O(6)-alkylguanine-DNA alkyltransferase (AGT), also known as O(6)-methylguanine-DNA methyltransferase (MGMT), is the DNA repair protein responsible for removing alkylation adducts from the O(6)-position of guanine in DNA. The promoter CpG island hypermethylation-associated gene silencing of MGMT is associated with a wide spectrum of human tumors. This epigenetic inactivation of MGMT has two main consequences in human cancer. First, it uncovers a new mutator pathway that causes the accumulation of G-to-A transition mutations that can affect genes required for genomic stability. Second, there is a strong and significant positive correlation between MGMT promoter hypermethylation and increased tumor sensitivity to alkylating drugs. These findings underline the importance of MGMT promoter hypermethylation in basic and translational cancer research. 相似文献
98.
Marco Antunes Telmo Pereira Jo?o V. Cordeiro Luis Almeida Antonio Jacinto 《The Journal of cell biology》2013,202(2):365-379
Epithelial wound healing relies on tissue movements and cell shape changes. Our work shows that, immediately after wounding, there was a dramatic cytoskeleton remodeling consisting of a pulse of actomyosin filaments that assembled in cells around the wound edge and flowed from cell to cell toward the margin of the wound. We show that this actomyosin flow was regulated by Diaphanous and ROCK and that it elicited a wave of apical cell constriction that culminated in the formation of the leading edge actomyosin cable, a structure that is essential for wound closure. Calcium signaling played an important role in this process, as its intracellular concentration increased dramatically immediately after wounding, and down-regulation of transient receptor potential channel M, a stress-activated calcium channel, also impaired the actomyosin flow. Lowering the activity of Gelsolin, a known calcium-activated actin filament–severing protein, also impaired the wound response, indicating that cleaving the existing actin filament network is an important part of the cytoskeleton remodeling process. 相似文献
99.
Emilio García‐Roselló Cástor Guisande Jacinto González‐Dacosta Juergen Heine Patricia Pelayo‐Villamil Ana Manjarrás‐Hernández Antonio Vaamonde Carlos Granado‐Lorencio 《Ecography》2013,36(11):1202-1207
The ModestR package consists of three applications: MapMaker, DataManager and MRFinder. MapMaker facilitates making range maps by drawing the areas, by importing existing data or using the Global Biodiversity Information Facility portal. It can discriminate between different habitats, thereby making data cleaning tasks easier. DataManager allows the management of taxonomically structured databases for range maps. MRFinder supports querying ModestR databases to find the species present in specific areas. Possible applications include the compilation and management of species distribution databases, cleaning data and computing aggregated data to perform subsequent analyses in other packages thanks to emphasized interoperability. 相似文献
100.