副沙鳅属的多变量形态分析

采用多变量分析方法对副沙鳅属Parabotia的外部形态进行了主成分分析,在27个测量性状的第1、第2主成分散布图上显示,副沙鳅属的外部形态存在着3个具有明显差异的种组:即点面副沙鳅,双斑副沙鳅、武昌副沙鳅和花斑副沙鳅,漓江副沙鳅和小副沙鳅3个种组.主成分负荷值还进一步表明,6种副沙鳅属外部度量性状的差异有多元化的倾向.结合定性特征的观察确定了副沙鳅属6个种的有效性.     

不同类型磁场对细胞作用的生物学研究

本文就不同参数的磁场的细胞生物学效应研究进行了综述 ,总结了不同类型不同物理参数的磁场对细胞生物学效应的研究成果 ,结合实验结果对磁场生物学效应的可能物理机制进行了初步探讨 ,并对磁场的细胞生物学效应的研究前景进行了展望。     

SANI-Severe Asthma Network in Italy: a way forward to monitor severe asthma

Even if severe asthma (SA) accounts for 5–10% of all cases of the disease, it is currently a crucial unmet need, owing its difficult clinical management and its high social costs. For this reason several networks, focused on SA have been organized in some countries, in order to select these patients, to recognize their clinical features, to evaluate their adherence, to classify their biological/clinical phenotypes, to identify their eligibility to the new biologic therapies and to quantify the costs of the disease. Aim of the present paper is to describe the ongoing Italian Severe Asthma Network (SANI). Up today 49 centres have been selected, widespread on the national territory. Sharing the same diagnostic protocol, data regarding patients with SA will be collected and processed in a web platform. After their recruitment, SA patients will be followed in the long term in order to investigate the natural history of the disease. Besides clinical data, the cost/benefit evaluation of the new biologics will be verified as well as the search of peculiar biomarker(s) of the disease.     

短日照对于洋麻叶形态变化的影响

洋麻(Hibiscus cannabinus)一生中叶形态的变化有着一定的规律性(雅库希金1947)。茎上基部的叶子为锯齿卵形,中部为深裂叶,叶子的分裂程度随着叶子的层次逐渐加大,菜片由3裂、5裂、发展到7裂。以后分裂的程度开始下降由7裂降到5裂、3裂。顶端的叶子篇锯齿狭长叶。根据以上的现象,可以看出随着洋麻发育的进程叶片分裂的程度有着周期性的变化。洋麻可以用缩短光照的处理来加速它的开花结实。在短光照条件下的洋麻是否因为光照期的缩短加速了叶形态周期性的变化?当洋麻从短光照的条件下进入长光照之     

Editorial

Viral diseases were largely untreatable 40 years ago. The first antivirals were developed in the 1960s, mostly to deal with herpes viruses, and were found using traditional trial-and-error drug discovery     

切应力对内皮细胞膜微粘度的影响

目的：研究切应力对内皮细胞（EC）膜微粘度的影响。材料和方法：将EC置于脉动循环装置中,分别施加15dyne/cm^2,50dyne/cm^2,30Odyne/cm^2切应力,作用Oh,1h,2h,4h,6h,10h后,利用带偏振器的荧光分光光度计测量膜微粘度,结果：切应力使膜微粘度增加,且切应力越高,膜微粘度增加幅度越大。切应力作用4h,EC膜微粘度升至最高,4h-10h,膜微粘度开始缓慢恢复,但仍比静态对照显著升高,结论：在切应力作用下,EC膜微粘度增加,切应力是AS的致病因素,动脉狭窄处和大中动脉分叉处是AS好发的危险部位,也是防治的重点。     

Genetic analysis of fluvastatin response and dyslipidemia in renal transplant recipients

The Assessment of Lescol in Renal Transplantation clinical trial demonstrated the efficacy of fluvastatin in reducing cardiovascular (CV) disease in renal transplant recipients. The study included a voluntary pharmacogenetic component, enrolling 1,404 patients, which allowed association testing of baseline measures and longitudinal analysis of the 707 fluvastatin-treated and 697 placebo-treated individuals. A candidate gene approach, examining 42 polymorphisms in 18 genes, was used to test for association between selected polymorphisms and major adverse cardiac events, graft failure, change in LDL and HDL cholesterol, and baseline LDL and HDL cholesterol. Reported associations between cholesteryl ester transfer protein (CETP) and baseline HDL cholesterol were replicated, with four previously implicated single nucleotide polymorphisms significantly associated in males and one in females; tests of reported associations between CETP and CV disease yielded varying results. We found no evidence for genetic factors affecting fluvastatin response. Polymorphisms in 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) previously reported to affect the efficacy of pravastatin did not show a similar effect on the reduction of LDL cholesterol by fluvastatin.     

菱纹叶蝉属中国种类记要(同翅目,叶蝉科,殃叶蝉亚科)

记述中国菱纹叶蝉属Hishimonus Ishihara 17种,其中有2新种,即长突菱纹叶蝉H.prolongatus sp.nov.和褐斑菱纹叶蝉H.fuscomaculatus sp.nov..新种模式标本保存在贵州大学昆虫研究所.     

等彩蝇属五新种(双翅目:丽蝇科)

等彩蝇属的研究,国外做过很多工作,国内近年陆续有报道(方建明、范滋德,1984,1985,1986),本文报道5个新种,3个中国新纪录,均采自云南。模式标本存中国科学院昆明动物研究所。