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51.
Anand Kumar Seema Singh Satyajit Pradhan Ram C Shukla Mumtaz A Ansari Tej B Singh Rohit Shyam Saroj Gupta 《World journal of surgical oncology》2007,5(1):1-6
Background
Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited disease. It is relatively recent that type 2C was identified as a separate group solely presenting with pheochromocytomas. As an illustration, an interesting case is presented of a pregnant woman with refractory hypertension. It proved to be the first manifestation of bilateral pheochromocytomas. The family history may indicate the diagnosis, but only identification of a germ line mutation in the DNA of a patient will confirm carriership.Case presentation
A 27 year pregnant patient with intra uterine growth retardation presented with hypertension and pre-eclampsia. Magnetic resonance imaging revealed bilateral adrenal pheochromocytoma. She underwent laparoscopic adrenelectomy and a missense mutation (Gly93Ser) in exon 1 of the VHL gene on chromosome 3 (p25 - p26) was shown in the patient, her father and her daughter confirming the diagnosis of VHL.Conclusion
In almost all VHL families molecular genetic analysis of DNA will demonstrate an inherited mutation. Because of the involvement in several organs, periodic clinical evaluation should take place in a well coordinated, multidisciplinary setting. VHL disease can be classified into several subtypes. VHL type 2C patients present with pheochromocytomas without evidence of haemangioblastomas in the central nervous system and/or retina and a low risk of renal cell carcinoma. Therefore, in such families, periodic clinical screening can be focussed on pheochromocytomas. 相似文献52.
Ghosh Chiranjit Patra Debashis Bala Niranjan Majumder Indira Sepay Nayim Mukhopadhyay Prabuddha Das Sukhen Kundu Rita Drew Michael G. B. León Armando Rafael Ghosh Tapas Pradhan Manik 《Biometals》2022,35(3):499-517
BioMetals - A family of dioxidovanadium(V) complexes (1–4) of the type [Na(H2O)x]+[VVO2(HL1?4)]? (x?=?4, 4.5 and 7) where HL2? represents the dianionic form of... 相似文献
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Effect of feeding Jerusalem artichoke (Helianthus tuberosus) root as prebiotic on nutrient utilization,fecal characteristics and serum metabolite profile of captive Indian leopard (Panthera pardus fusca) fed a meat‐on‐bone diet
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S.K. Pradhan A. Das S.S. Kullu M. Saini A.K. Pattanaik N. Dutta A.K. Sharma 《Zoo biology》2015,34(2):153-162
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Biomining comprises of processing and extraction of metal from their ores and concentrates using microbial techniques. Currently this is used by the mining industry to extract copper, uranium and gold from low grade ores but not for low grade manganese ore in industrial scale. The study of microbial genomes, metabolites and regulatory pathways provide novel insights to the metabolism of bioleaching microorganisms and their synergistic action during bioleaching operations. This will promote understanding of the universal regulatory responses that the biomining microbial community uses to adapt to their changing environment leading to high metal recovery. Possibility exists of findings ways to imitate the entire process during industrial manganese biomining endeavor. This paper reviews the current status of manganese biomining research operations around the world, identifies factors that drive the selection of biomining as a processing technology, describes challenges in exploiting these innovations, and concludes with a discussion of Mn biomining’s future. 相似文献