中国点池蝇属一新种：双翅目：蝇科

本文记述我国点池蝇属１新种：山西点池蝇Ｓｐｉｌｏｇｏｎａｓｈａｎｘｉｅｎｓｉｓｓｐ．ｎｏｖ．。     

赖氨酸特异性组蛋白去甲基化酶1与白血病的研究进展

表观遗传学是后基因组时代兴起的一门新学科,它使人们认识到包括DNA甲基化、组蛋白修饰、染色质重塑及非编码RNA调控在内的修饰也可以记载遗传信息;并且许多表观遗传改变是可逆的,对表观遗传修饰和调控的研究已成为生命科学的热点和发展前沿。2004年发现的赖氨酸特异性组蛋白去甲基化酶1(LSD1)是第一个真正意义上的组蛋白赖氨酸去甲基化酶,使人们认识到组蛋白甲基化是一个动态的过程,通过组蛋白甲基转移酶和去甲基化酶的相互作用,动态地调控基因转录的激活和抑制等生物学过程。这重新定义了组蛋白甲基化,同时也为进一步深入研究组蛋白修饰提供了新的途径。我们在此简要介绍LSD1的结构与功能、LSD1与白血病的关系,LSD1在白血病的发生和发展中发挥重要作用,是一个潜在的治疗白血病的靶基因。     

等彩蝇属五新种(双翅目:丽蝇科)

等彩蝇属的研究,国外做过很多工作,国内近年陆续有报道(方建明、范滋德,1984,1985,1986),本文报道5个新种,3个中国新纪录,均采自云南。模式标本存中国科学院昆明动物研究所。     

Synthesis and Biological Activities of Nicotinaldehyde Based 1,4-Dihydropyridinedicarboxylates

Russian Journal of Bioorganic Chemistry - 1,4-Dihydropyridinecarboxylates were prepared by the reaction of nicotinaldehydes with aminocrotonoates in the presence of p-TsOH at room temperature. The...     

Epidemiology and Outcome of Severe Sepsis and Septic Shock in Intensive Care Units in Mainland China

Introduction

Information about sepsis in mainland China remains scarce and incomplete. The purpose of this study was to describe the epidemiology and outcome of severe sepsis and septic shock in mixed ICU in mainland China, as well as the independent predictors of mortality.

Methods

We performed a 2-month prospective, observational cohort study in 22 closed multi-disciplinary intensive care units (ICUs). All admissions into those ICUs during the study period were screened and patients with severe sepsis or septic shock were included.

Results

A total of 484 patients, 37.3 per 100 ICU admissions were diagnosed with severe sepsis (n = 365) or septic shock (n = 119) according to clinical criteria and included into this study. The most frequent sites of infection were the lung and abdomen. The overall ICU and hospital mortality rates were 28.7% (n = 139) and 33.5% (n = 162), respectively. In multivariate analyses, APACHE II score (odds ratio[OR], 1.068; 95% confidential interval[CI], 1.027–1.109), presence of ARDS (OR, 2.676; 95%CI, 1.691–4.235), bloodstream infection (OR, 2.520; 95%CI, 1.142–5.564) and comorbidity of cancer (OR, 2.246; 95%CI, 1.141–4.420) were significantly associated with mortality.

Conclusions

Our results indicated that severe sepsis and septic shock were common complications in ICU patients and with high mortality in China, and can be of help to know more about severe sepsis and septic shock in China and to improve characterization and risk stratification in these patients.     

Telomere and telomerase in oncology

Telomere and cell replicative senescenceTelomeres, which are located at the end of chro-mosome, are crucial to protect chromosome againstdegeneration, rearrangment and end to end fusion[1].Human telomeres are tandemly repeated units of thehexanucleotide TTAGGG. The estimated length oftelomeric DNA varies from 2 to 20 kilo base pairs,depending on factors such as tissue type and hu-man age. The buck of telomeric DNA is double-stranded, but the end of telomeric DNA consists of3' overhang of…     

小头叶蝉属系统分类研究（同翅目：叶蝉科）

记述世界小头叶蝉属Placidus Distant昆虫9种,其中包括4个新种。条痕小头叶蝉Placidus striolatus,sp.nov. 乌樽小头叶蝉Placidus nigrocupuliferou,sp.nov.分布于云省,花顶小头叶蝉Placidus flosifronus,sp.nov.分布于湖南省,密齿小叶蝉Placidus dentatus,sp.nov。分布于四川省。中列出了所有9种小头叶蝉的名录并编制了分布检索表。新种模式标本分别保存于西北农林科技大学昆虫博物馆和中国科学院动物研究所（IZAS）。新种模式标本和示差鉴别特征如下：条痕小叶蝉Placidus striolatus,新种,正模：♂（IZAS）,云南省,大围山,1350m,1956-V-22,邦浦洛夫采。该新种与P.hornei Distant相近,但其雄性生殖瓣侧面观近三角形,尾节侧瓣向后渐狭,阳茎端部近1／3处具数条长印痕,阳茎产端部腹缘锯齿状,可以与后相区别。花顶小头叶蝉Palcidus flosifrontus,新种（图3）,正模♂,南非,郴州莽山,1985－Ⅶ－31,张雅林,柴勇辉采。该新种与P.hornei Distant相近,但其阳茎基部两侧所具有一对长的带状突不同于小头叶蝉属Placidus所有其他种类。密齿小头叶蝉Plasidus dentatus,新种（图4）,模：♂（IZAS）,四川省,马尔康,1961－Ⅵ,李贵富采。该新种与P.brunneus Kuoh相近,但其小盾片中域横刻痕不明显,连索“Y”型,阳茎端部部侧区密生小齿突,可与后明显相区分,乌樽小头叶蝉Placidus nigrocupuliferous,新种（图5）,正模：♂,云南省,勐养,750m,1991-Ⅵ－9,王应伦,田润刚采。该新种与P.hornei Distant和P.bruneus Kuoh相近,但其阳基侧突呈“S”形且基部1／3膨大,阳茎侧面观呈“Y”形,腹面一支明显比背方一支狭,可与后两种明显区分。     

平腹小蜂属四新种记述：（膜翅目：旋小蜂科）

本文记述平腹小蜂属Ａｎａｓｔａｔｕｓ ４新种,即石城平腹小蜂Ａ;Ｓｈｉｃｈｅｎｇｅｎｓｉｓ,ｓｐ．ｎｏｖ;德兴平腹小蜂;Ａ;ｄｅｘｉｎｇｅｎｓｉｓ,ｓｐ．ｎｏｖ;麻纹蝽平腹小蜂Ａ;Ｆｕｌｌｏｉ,ｓｐ．ｎｏｖ。及黄褐平腹小蜂Ａ;ｆｇｌａｖｉｐｅｓ,ｓｐ．ｎｏｖ。模式标本保存于东西农业大学植物保护系昆虫标杯室。     

香港次生林下植物菌根的调查

本文报道了香港６４种野生植物根系天然感染菌根菌的状况：９８．４％的植物都不同程度地感染上了菌根菌,９８．１％的根样发现受内生菌根（ＶＡＭ）的感染,其中小叶青冈（Ｑｕｅｒｃｕｓｍｙｒｓｉｎａｅｆｏｌｉａ）同时受外生菌根（ＥＣＭ）和内生菌根的感染。该研究揭示了香港次生林植物在自然条件下受菌根菌感染的普遍性,为进一步探讨华南地区菌根与退化地区植物群落演替的关系提供了重要的本底资料。     

华北璐蜡蝉属一新种(同翅目:璐蜡蝉科)

本文记述了璐蜡蝉科Lophopidae华北璐蜡蝉属Boresinia 1新种,模式标本存放在西北农业大学昆虫博物馆。