全文获取类型
收费全文 | 12196篇 |
免费 | 237篇 |
国内免费 | 37篇 |
出版年
2023年 | 33篇 |
2022年 | 154篇 |
2021年 | 319篇 |
2020年 | 167篇 |
2019年 | 268篇 |
2018年 | 426篇 |
2017年 | 404篇 |
2016年 | 702篇 |
2015年 | 953篇 |
2014年 | 810篇 |
2013年 | 1325篇 |
2012年 | 980篇 |
2011年 | 737篇 |
2010年 | 860篇 |
2009年 | 729篇 |
2008年 | 694篇 |
2007年 | 654篇 |
2006年 | 591篇 |
2005年 | 431篇 |
2004年 | 213篇 |
2003年 | 132篇 |
2002年 | 143篇 |
2001年 | 52篇 |
2000年 | 161篇 |
1999年 | 82篇 |
1998年 | 67篇 |
1997年 | 61篇 |
1996年 | 35篇 |
1995年 | 26篇 |
1994年 | 9篇 |
1993年 | 15篇 |
1992年 | 36篇 |
1991年 | 18篇 |
1990年 | 12篇 |
1989年 | 16篇 |
1988年 | 9篇 |
1987年 | 13篇 |
1986年 | 7篇 |
1985年 | 10篇 |
1984年 | 7篇 |
1983年 | 9篇 |
1982年 | 10篇 |
1981年 | 11篇 |
1980年 | 10篇 |
1979年 | 8篇 |
1978年 | 8篇 |
1976年 | 6篇 |
1974年 | 5篇 |
1972年 | 5篇 |
1935年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
82.
Donatella Marazziti Lionella Palego Chiara Mazzanti Stefano Silvestri Giovanni B. Cassano 《Chronobiology international》1995,12(2):100-105
Our study aimed to investigate the possible presence of seasonal changes in platelet phenolsulfotransferase (ST) in a group of 20 healthy, drug-free subjects of both sexes and between 24 and 37 years of age. Blood samples were taken four times a year in the period immediately following the equinoxes and the solstices. The results showed that both STs underwent seasonal changes: the lowest values were found in autumn and in winter, and the highest in the summer. A positive correlation between the two STs and the length of the photoperiod was observed in winter, whereas in the spring we detected a negative correlation between the TL ST and the photoperiod length. Future studies should clarify whether platelet ST of patients with mood disorders shows a similar seasonality. 相似文献
83.
Macarena Gomez-Lira Antonella Sangalli Monica Mottes Chiara Perusi Pier Franco Pignatti Nicolò Rizzuto Alessandro Salviati 《Human genetics》1995,96(4):417-422
-Hexosaminidase gene mutations were analyzed in two adult-onset Sandhoff disease Italian patients by PCR analysis of a common known mutation (5) and by heteroduplex analysis of genomic and RT-PCR DNA fragments, covering the whole gene. The patients' genotypes were 5/C1214T, and G890A/C1214T, respectively. As mutation C1214T (Pro405Leu) is also present in the other two late-onset cases so far described, we suggest that C1214T is a common mutation in this type of Sandhoff disease. Mutation G890A (Cys297Tyr) is a novel mutation which presumably causes altered processing of the pro chain. 相似文献
84.
Shu’a Yagev Michael Heller Arié Pinson 《In vitro cellular & developmental biology. Plant》1984,20(12):893-898
Summary Postnatal rat heart cells in culture enriched with respect to muscle cells were obtained by either high density seeding or
by the replating technique. [3H]Thymidine incorporation to DNA and the enzymatic pattern of cytoplasmic and lysosomal enzymes have been studied as a function
of the culture’s age, of seeding density, and replating. It was shown that (a) replating maintains predominance of myocyte
population for at least 2 wk in culture; (b) heavy seeding density allows homogeneous myocyte population for the 1st wk in
culture; and (c) the enzyme profile of the culture may serve as an indicator for the type of cell population in culture and
its state of differentiation.
This study was done as partial fulfilment of the M.Sc. thesis in Biochemistry (SY). Supported by grants from The Chief Scientist,
Ministry of Health, State of Israel; The Ministry of Education and Sciences, State of Niedersachssen (FRG); and The Foundation
for Heart Research from Mr. and Mrs. D. Vidal-Madjar, Paris, France. 相似文献
85.
86.
3H-thymidine incorporation and DNA-polymerase activity during early hours of wheat embryo germination at two viability levels
have been studied. The patterns of two biosynthetic activities, as well as the dependence of DNA synthesis on protein synthesis,
indicated the presence of a delay in the early phase of imbibition of the aged embryos with respect to viable germs. 相似文献
87.
Brigitte Tréton Marie -Thérèse Le Dall H. Heslot 《Applied microbiology and biotechnology》1978,6(1):67-77
Summary We investigated the excretion of citric and isocitric acids in a strain of Saccharomycopsis lipolytica grown on either n-paraffins, glucose, or glycerol. These acids were excreted in the ratio of 67:33 on n-paraffins and roughly 92:8 on either glucose or glycerol. However, with all the carbon sources used, the relative amount of isocitric acid in the intracellular pool remained below 10%. The assimilation of citric and isocitric acids was prevented when glucose or glycerol were the carbon sources, but not when n-paraffins were used. Citric acid stopped isocitric acid assimilation. These phenomena of selective assimilation and/or uptake might explain the variations observed in the ratio of citric to isocitric acids excreted on different carbon sources. 相似文献
88.
Biochemical changes of rat brain membranes with aging 总被引:4,自引:0,他引:4
Gabriella Calderini Anna Chiara Bonetti Antonio Battistella Fulton Timm Crews Gino Toffano 《Neurochemical research》1983,8(4):483-492
Modification of membrane composition and enzymatic activities both in total brain homogenate and purified synaptic plasma membrane of 3 and 24 month old rats has been investigated. Protein, cholesterol and phospholipid content and (Na+, K+)ATPase and 2',3' cyclic nucleotide phosphohydrolase activities were determined. The major changes occurred in the whole homogenate where a general increase in total protein and cholesterol content with age and a significant increase of the cholesterol/phospholipids molar ratio has been detected. In S.P.M. aging process induced a decrease of protein, cholesterol and phospholipids content associated with an increased membrane viscosity and a decrease of delta E. These data are consistent with a change in the structural organization and in the distribution pattern of different cell population in the aging brain. A possible artifactual effect of freezing on the reported parameter is also discussed. 相似文献
89.
90.