全文获取类型
收费全文 | 122篇 |
免费 | 14篇 |
出版年
2023年 | 2篇 |
2022年 | 1篇 |
2021年 | 2篇 |
2020年 | 1篇 |
2019年 | 1篇 |
2017年 | 3篇 |
2016年 | 1篇 |
2015年 | 2篇 |
2014年 | 3篇 |
2013年 | 5篇 |
2012年 | 6篇 |
2011年 | 9篇 |
2010年 | 4篇 |
2009年 | 2篇 |
2008年 | 3篇 |
2007年 | 2篇 |
2006年 | 8篇 |
2005年 | 1篇 |
2004年 | 2篇 |
2003年 | 7篇 |
2002年 | 3篇 |
2001年 | 3篇 |
2000年 | 10篇 |
1999年 | 3篇 |
1998年 | 5篇 |
1997年 | 4篇 |
1996年 | 2篇 |
1995年 | 3篇 |
1994年 | 2篇 |
1993年 | 1篇 |
1992年 | 7篇 |
1991年 | 2篇 |
1990年 | 2篇 |
1989年 | 3篇 |
1988年 | 6篇 |
1987年 | 1篇 |
1986年 | 3篇 |
1985年 | 2篇 |
1984年 | 3篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1979年 | 2篇 |
1978年 | 1篇 |
排序方式: 共有136条查询结果,搜索用时 265 毫秒
61.
62.
63.
N Raich V Mignotte A Dubart D Beaupain P Leboulch M Romana C Chabret P Charnay T Papayannopoulou M Goossens 《The Journal of biological chemistry》1989,264(17):10186-10192
64.
65.
66.
67.
Regulated expression of cloned human fetal A gamma-globin genes introduced into murine erythroleukemia cells 总被引:7,自引:0,他引:7
We have analysed the expression of cloned human fetal gamma-globin genes introduced into murine erythroleukemia cells by a protoplast fusion procedure. Both the wild-type a gamma-globin gene and a mutant derivative related to a phenotype of hereditary persistence of fetal hemoglobin were studied. In both cases the level of gamma-globin mRNA increased by a factor of approximately sevenfold when erythroid cell differentiation was induced by treatment with hexamethylenebisacetamide. Thus, the regulation of the expression of the cloned fetal A gamma-globin gene in murine erythroleukemia cells resembled that of cloned adult beta-globin genes. 相似文献
68.
69.
70.
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation 总被引:5,自引:0,他引:5
López-Bendito G Cautinat A Sánchez JA Bielle F Flames N Garratt AN Talmage DA Role LW Charnay P Marín O Garel S 《Cell》2006,125(1):127-142
Neuronal migration and axon guidance constitute fundamental processes in brain development that are generally studied independently. Although both share common mechanisms of cell biology and biochemistry, little is known about their coordinated integration in the formation of neural circuits. Here we show that the development of the thalamocortical projection, one of the most prominent tracts in the mammalian brain, depends on the early tangential migration of a population of neurons derived from the ventral telencephalon. This tangential migration contributes to the establishment of a permissive corridor that is essential for thalamocortical axon pathfinding. Our results also demonstrate that in this process two different products of the Neuregulin-1 gene, CRD-NRG1 and Ig-NRG1, mediate the guidance of thalamocortical axons. These results show that neuronal tangential migration constitutes a novel mechanism to control the timely arrangement of guidance cues required for axonal tract formation in the mammalian brain. 相似文献