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991.
Helen Belefant-Miller 《Plant Growth Regulation》2012,66(3):255-264
Straighthead is a physiological disorder of rice causing sterility. A particular characteristic of straighthead is panicles that remain upright because of the light weight of the unfilled grains, the hulls of which may be distorted into a crescent or parrot-beak shape. Monosodium methanearsenate (MSMA) was used in this study, to induce straighthead-like sterility symptoms in rice. Rating scales were developed to quantify the specific symptoms of straighthead (grain distortion, rachis curvature, panicle exsertion, and panicle weight), which were used to examine MSMA-induced straighthead in a greenhouse setting. Different rice cultivars were surveyed for their specific responses to MSMA, to identify targets for focus in rice breeding that differ in their responses. MSMA altered the pattern of anthesis so that flowering continued for a longer period of time although the initial flowering time and total panicle number were not affected. Early flowering panicles were less affected by MSMA than later flowering panicles. While all previous studies of MSMA-induced straighthead used MSMA applied at or before planting, a time course of MSMA application showed a time point for application at about the V4 (4-leaf) stage when the sterility symptoms were reduced and then an interval of time from about V6 to V8 when applications resulted in symptoms more severe than application at planting. A greenhouse temperature study demonstrated that lowering the temperature of the roots reduced the severity of the responses. MSMA is valuable as a trigger to induce a set of sterility symptoms so that the underlying physiological, biochemical, and genetic causes can be studied, and which may have implications for other sterility conditions. 相似文献
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993.
Young Ho Lee Sang-Cheol Bae Sung Jae Choi Jong Dae Ji Gwan Gyu Song 《Molecular biology reports》2012,39(12):10671-10679
The aim of this study was to explore whether FAS ?670?A/G and ?1,377?G/A polymorphisms confer susceptibility to autoimmune rheumatic diseases. A meta-analysis was conducted on the associations between the FAS ?670?A/G and ?1,377?G/A polymorphisms and autoimmune rheumatic diseases using allele contrast, a recessive model, a dominant model, and an additive model. Thirteen articles with 21 comparison studies (16 on FAS ?670?A/G and 5 on ?1,377?G/A polymorphisms) including systemic lupus erythematosus (SLE), four systemic sclerosis, four Sjogren’s syndrome, three rheumatoid arthritis (RA), one juvenile idiopathic arthritis, and one spondyloarthropathy were available for the meta-analysis. Meta-analysis revealed an association between rheumatic diseases and the FAS ?670?A/G polymorphism in the dominant model (odds ratio [OR]?=?0.761, 95?% confidence interval [CI]?=?0.621–0.932, p?=?0.008]. Stratification by ethnicity indicated an association between the FAS ?670?G allele carrier and rheumatic diseases in Asian (OR?=?0.569, 95?% CI?=?0.409–0.791, p?=?0.001). Furthermore, stratification by disease indicated an association between the FAS ?670?G allele carrier and SLE and RA (OR?=?0.578, 95?% CI?=?0.358–0.934, p?=?0.025; OR?=?0.609, 95?% CI?=?0.398–0.934, p?=?0.023, respectively). The FAS ?670?G allele was negatively associated with SLE susceptibility. Meta-analysis of the FAS ?1,377?G/A polymorphism stratified by disease showed an association between the FAS ?1,377 A allele and SLE (OR?=?0.783, 95?% CI?=?0.613–0.997, p?=?0.047). Meta-analyses using the dominant model also showed a significant association in SLE (OR?=?0.712, 95?% CI?=?0.528–0.961, p?=?0.027). This meta-analysis demonstrates that the FAS ?670?A/G polymorphism confers susceptibility to rheumatic diseases in Asians and SLE and RA, and the FAS ?1,377?G/A polymorphism is associated with SLE susceptibility. 相似文献
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998.
Matvey Roshchin Pavel M. Balaban 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》2012,198(2):145-158
We investigated the role of serotonin (5HT) and dopamine (DA) in the regulation of olfactory system function and odor-evoked tentacle movements in the snail Helix. Preparations of the posterior tentacle (including sensory pad, tentacular ganglion and olfactory nerve) or central ganglia with attached posterior tentacles were exposed to cineole odorant and the evoked responses were affected by prior application of 5HT or DA or their precursors 5-hydroxytryptophan (5HTP) and l-DOPA, respectively. 5HT applications decreased cineole-evoked responses recorded in the olfactory nerve and hyperpolarized the identified tentacle retractor muscle motoneuron MtC3, while DA applications led to the opposite changes. 5HTP and l-DOPA modified MtC3 activity comparable to 5HT and DA action. DA was also found to decrease the amplitude of spontaneous local field potential oscillations in the procerebrum, a central olfactory structure. In vivo studies demonstrated that injection of 5HTP in freely moving snails reduced the tentacle withdrawal response to aversive ethyl acetate odorant, whereas the injection of l-DOPA increased responses to “neutral” cineole and aversive ethyl acetate odorants. Our data suggest that 5HT and DA affect the peripheral (sensory epithelium and tentacular ganglion), the central (procerebrum), and the single motor neuron (withdrawal motoneuron MtC3) level of the snail’s nervous system. 相似文献
999.
Tore Eid Kevin Behar Ronnie Dhaher Argyle V. Bumanglag Tih-Shih W. Lee 《Neurochemical research》2012,37(11):2339-2350
Glutamine synthetase (GS, E.C. 6.3.1.2) is a ubiquitous and highly compartmentalized enzyme that is critically involved in several metabolic pathways in the brain, including the glutamine-glutamate-GABA cycle and detoxification of ammonia. GS is normally localized to the cytoplasm of most astrocytes, with elevated concentrations of the enzyme being present in perivascular endfeet and in processes close to excitatory synapses. Interestingly, an increasing number of studies have indicated that the expression, distribution, or activity of brain GS is altered in several brain disorders, including Alzheimer’s disease, schizophrenia, depression, suicidality, and mesial temporal lobe epilepsy (MTLE). Although the metabolic and functional sequelae of brain GS perturbations are not fully understood, it is likely that a deficiency in brain GS will have a significant biological impact due to the critical metabolic role of the enzyme. Furthermore, it is possible that restoration of GS in astrocytes lacking the enzyme could constitute a novel and highly specific therapy for these disorders. The goals of this review are to summarize key features of mammalian GS under normal conditions, and discuss the consequences of GS deficiency in brain disorders, specifically MTLE. 相似文献
1000.
Rebeccah A. Waterworth Richard A. Redak Jocelyn G. Millar 《Journal of Insect Behavior》2012,25(3):287-296
In laboratory bioassays, male Pseudococcus viburni (Signoret) and Planococcus ficus Signoret were attracted to body sections of females that included the metathoracic legs. Extracts of the metathoracic legs of female P. ficus were much more attractive to males than extracts of the other legs, and males exhibited copulatory behavior towards these extracts. Scanning electron microscopy showed the presence of translucent pores on the coxae of mature but not immature females. Collectively, the data suggest that the female-produced sex pheromones of these species are released from the metathoracic legs, probably from the translucent pores. 相似文献