全文获取类型
收费全文 | 4075篇 |
免费 | 359篇 |
国内免费 | 3篇 |
出版年
2023年 | 17篇 |
2022年 | 29篇 |
2021年 | 86篇 |
2020年 | 60篇 |
2019年 | 60篇 |
2018年 | 92篇 |
2017年 | 67篇 |
2016年 | 129篇 |
2015年 | 233篇 |
2014年 | 212篇 |
2013年 | 268篇 |
2012年 | 382篇 |
2011年 | 310篇 |
2010年 | 221篇 |
2009年 | 198篇 |
2008年 | 274篇 |
2007年 | 274篇 |
2006年 | 217篇 |
2005年 | 180篇 |
2004年 | 196篇 |
2003年 | 185篇 |
2002年 | 154篇 |
2001年 | 52篇 |
2000年 | 28篇 |
1999年 | 33篇 |
1998年 | 39篇 |
1997年 | 25篇 |
1996年 | 17篇 |
1995年 | 18篇 |
1994年 | 22篇 |
1993年 | 20篇 |
1992年 | 29篇 |
1991年 | 22篇 |
1990年 | 28篇 |
1989年 | 12篇 |
1988年 | 16篇 |
1987年 | 23篇 |
1986年 | 10篇 |
1985年 | 18篇 |
1984年 | 20篇 |
1983年 | 15篇 |
1982年 | 16篇 |
1981年 | 13篇 |
1980年 | 8篇 |
1979年 | 10篇 |
1978年 | 9篇 |
1976年 | 13篇 |
1975年 | 11篇 |
1974年 | 10篇 |
1971年 | 11篇 |
排序方式: 共有4437条查询结果,搜索用时 15 毫秒
81.
Aline Planchon Gaëlle Durambur Jean‐Baptiste Besnier Carole Plasson Bruno Gügi Sophie Bernard Annabelle Mrieau Jean‐Paul Trouv Caroline Dubois Karine Laval Azeddine Driouich Jean‐Claude Mollet Richard Gattin 《Plant, cell & environment》2021,44(1):304-322
In Normandy, flax is a plant of important economic interest because of its fibres. Fusarium oxysporum, a telluric fungus, is responsible for the major losses in crop yield and fibre quality. Several methods are currently used to limit the use of phytochemicals on crops. One of them is the use of plant growth promoting rhizobacteria (PGPR) occurring naturally in the rhizosphere. PGPR are known to act as local antagonists to soil‐borne pathogens and to enhance plant resistance by eliciting the induced systemic resistance (ISR). In this study, we first investigated the cell wall modifications occurring in roots and stems after inoculation with the fungus in two flax varieties. First, we showed that both varieties displayed different cell wall organization and that rapid modifications occurred in roots and stems after inoculation. Then, we demonstrated the efficiency of a Bacillus subtilis strain to limit Fusarium wilt on both varieties with a better efficiency for one of them. Finally, thermo‐gravimetry was used to highlight that B. subtilis induced modifications of the stem properties, supporting a reinforcement of the cell walls. Our findings suggest that the efficiency and the mode of action of the PGPR B. subtilis is likely to be flax variety dependent. 相似文献
82.
Carole Émile 《Option/Bio》2021,32(631-632):18-20
83.
This paper present the content of the Musée de l'Homme exhibition “Us and them: from prejudice to racism” and provides a detailed explanation of how this content has been presented to the public. In a second section of this paper we explain some of the analysis and concepts, from a biological anthropology perspective, that were the foundation of the exhibition and provides some information about the current situation in France. 相似文献
84.
Pierre Balmer William V.J. Hariton Beyza S. Sayar Vidhya Jagannathan Arnaud Galichet Tosso Leeb Petra Roosje Eliane J. Müller 《The Journal of cell biology》2021,220(4)
Epigenetic histone trimethylation on lysine 9 (H3K9me3) represents a major molecular signal for genome stability and gene silencing conserved from worms to man. However, the functional role of the H3K9 trimethylases SUV39H1/2 in mammalian tissue homeostasis remains largely unknown. Here, we use a spontaneous dog model with monogenic inheritance of a recessive SUV39H2 loss-of-function variant and impaired differentiation in the epidermis, a self-renewing tissue fueled by stem and progenitor cell proliferation and differentiation. Our results demonstrate that SUV39H2 maintains the stem and progenitor cell pool by restricting fate conversion through H3K9me3 repressive marks on gene promoters encoding components of the Wnt/p63/adhesion axis. When SUV39H2 function is lost, repression is relieved, and enhanced Wnt activity causes progenitor cells to prematurely exit the cell cycle, a process mimicked by pharmacological Wnt activation in primary canine, human, and mouse keratinocytes. As a consequence, the stem cell growth potential of cultured SUV39H2-deficient canine keratinocytes is exhausted while epidermal differentiation and genome stability are compromised. Collectively, our data identify SUV39H2 and potentially also SUV39H1 as major gatekeepers in the delicate balance of progenitor fate conversion through H3K9me3 rate-limiting road blocks in basal layer keratinocytes. 相似文献
85.
Theresa Farhat Amel Dudakovic Jay H. Chung Andre J. van Wijnen Ren St‐Arnaud 《Journal of cellular physiology》2021,236(2):1195-1213
86.
Cara A. Faillace Arnaud Sentis José M. Montoya 《Biological reviews of the Cambridge Philosophical Society》2021,96(5):1933-1950
Eco-evolutionary dynamics can mediate species and community responses to habitat warming and fragmentation, two of the largest threats to biodiversity and ecosystems. The eco-evolutionary consequences of warming and fragmentation are typically studied independently, hindering our understanding of their simultaneous impacts. Here, we provide a new perspective rooted in trade-offs among traits for understanding their eco-evolutionary consequences. On the one hand, temperature influences traits related to metabolism, such as resource acquisition and activity levels. Such traits are also likely to have trade-offs with other energetically costly traits, like antipredator defences or dispersal. On the other hand, fragmentation can influence a variety of traits (e.g. dispersal) through its effects on the spatial environment experienced by individuals, as well as properties of populations, such as genetic structure. The combined effects of warming and fragmentation on communities should thus reflect their collective impact on traits of individuals and populations, as well as trade-offs at multiple trophic levels, leading to unexpected dynamics when effects are not additive and when evolutionary responses modulate them. Here, we provide a road map to navigate this complexity. First, we review single-species responses to warming and fragmentation. Second, we focus on consumer–resource interactions, considering how eco-evolutionary dynamics can arise in response to warming, fragmentation, and their interaction. Third, we illustrate our perspective with several example scenarios in which trait trade-offs could result in significant eco-evolutionary dynamics. Specifically, we consider the possible eco-evolutionary consequences of (i) evolution in thermal performance of a species involved in a consumer–resource interaction, (ii) ecological or evolutionary changes to encounter and attack rates of consumers, and (iii) changes to top consumer body size in tri-trophic food chains. In these scenarios, we present a number of novel, sometimes counter-intuitive, potential outcomes. Some of these expectations contrast with those solely based on ecological dynamics, for example, evolutionary responses in unexpected directions for resource species or unanticipated population declines in top consumers. Finally, we identify several unanswered questions about the conditions most likely to yield strong eco-evolutionary dynamics, how better to incorporate the role of trade-offs among traits, and the role of eco-evolutionary dynamics in governing responses to warming in fragmented communities. 相似文献
87.
Arnaud Huguet Sylvain Bernard Rime El Khatib Martina I. Gocke Guido L. B. Wiesenberg Sylvie Derenne 《Geobiology》2021,19(1):75-86
Rhizoliths, that is, roots fossilized by secondary carbonates, have been known for ages and are increasingly used for paleoenvironmental reconstructions. However, knowledge about their formation mechanisms remains limited. This study reports the mineralogical and chemical characterization of rhizoliths at different stages of mineralization and fossilization in the Late Pleistocene loess–paleosol sequence of Nussloch (SW Germany). Scanning electron microscopy coupled with elemental mapping and 13C solid‐state nuclear magnetic resonance were used to concomitantly characterize the mineral and organic matter of the rhizoliths. These joint analyses showed for the first time that large rhizoliths are not necessarily remains of single large roots but consist of numerous microrhizoliths as remains of fine roots, formed mainly by calcium carbonates with only low amounts of Mg and Si. They further revealed that the precipitation of secondary carbonates occurs not only around, but also within the plant root and that fossilization leads to the selective preservation of recalcitrant root biopolymers—lignin and suberin. The precipitation of secondary carbonates was observed to occur first around fine roots, the epidermis acting as a first barrier, and then within the root, within the cortex cells, and even sometimes around the phloem and within the xylem. This study suggests that the calcification of plant roots starts during the lifetime of the plant and continues after its death. This has to be systematically investigated to understand the stratigraphic context before using (micro)rhizoliths for paleoenvironmental reconstructions in terrestrial sediments. 相似文献
88.
89.