全文获取类型
收费全文 | 704篇 |
免费 | 52篇 |
出版年
2023年 | 5篇 |
2022年 | 12篇 |
2021年 | 11篇 |
2020年 | 11篇 |
2019年 | 14篇 |
2018年 | 14篇 |
2017年 | 18篇 |
2016年 | 16篇 |
2015年 | 36篇 |
2014年 | 45篇 |
2013年 | 40篇 |
2012年 | 63篇 |
2011年 | 49篇 |
2010年 | 22篇 |
2009年 | 30篇 |
2008年 | 51篇 |
2007年 | 37篇 |
2006年 | 37篇 |
2005年 | 34篇 |
2004年 | 25篇 |
2003年 | 18篇 |
2002年 | 27篇 |
2001年 | 12篇 |
2000年 | 9篇 |
1999年 | 9篇 |
1998年 | 6篇 |
1997年 | 5篇 |
1996年 | 2篇 |
1995年 | 2篇 |
1994年 | 9篇 |
1993年 | 6篇 |
1992年 | 7篇 |
1991年 | 8篇 |
1990年 | 9篇 |
1989年 | 6篇 |
1988年 | 4篇 |
1987年 | 5篇 |
1986年 | 7篇 |
1985年 | 5篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1982年 | 4篇 |
1981年 | 2篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1977年 | 2篇 |
1975年 | 3篇 |
1974年 | 3篇 |
1973年 | 2篇 |
1959年 | 1篇 |
排序方式: 共有756条查询结果,搜索用时 15 毫秒
751.
752.
753.
Group-specific component (Gc) polymorphism was investigated in 559 individuals from Aragon. The gene frequencies were compared to those reported for other European populations. 相似文献
754.
JoséS. Casas Eduardo E. Castellano María C. Rodríguez-Argüelles Agustín Sánchez José Sordo Julio Zukerman-Schpector 《Inorganica chimica acta》1997,260(2):4059-188
The title compoud, [TlMe2(HL)(H2O)] (HL = monoanion of pyridoxal thiosemicarbazone), crystallizers in the triclinic space group
, No. 2). The HL−anion coordinates to the thallium atom, in an unusual mode through the S atom (Tl-S = 2.832(1) Å), and also forms a weak bond with the metal atom of a neighbouring molecule to make an asymmetric bridge (Tl′…S = 3.190(1) Å). The acidic proton retained in the thiosemicarbazonato anion is located on the oxygen of the phenolic hydroxyl group. The water molecule is only 2.630(4) Å from the metal, suggesting a rather strong bond that contrasts with the long distance between the thallium and the phenolic oxygen (Tl…O(1)′ = 3.124(4) Å). If both strong and weak intermolecular interactions are taken in account, the metal has distorted octahedral coordination with the methyl groups in apical positions. The solid state IR spectrum and 1H, 13C and 205Tl NMR spectra in DMSO solution are also discussed. 相似文献
755.
Vivianne J. Goosens Carmine G. MonteferranteJan Maarten van Dijl 《Biochimica et Biophysica Acta (BBA)/Molecular Cell Research》2014
The twin-arginine protein translocation (Tat) system has a unique ability to translocate folded and co-factor-containing proteins across lipid bilayers. The Tat pathway is present in bacteria, archaea and in the thylakoid membranes of chloroplasts and, depending on the organism and environmental conditions, it can be deemed important for cell survival, virulence or bioproduction. This review provides an overview of the current understanding of the Tat system with specific focus on Gram-positive bacteria. The ‘universal minimal Tat system’ is composed of a TatA and a TatC protein. However, this pathway is more commonly composed of two TatA-like proteins and one TatC protein. Often the TatA-like proteins have diverged to have two different functions and, in this case, the second TatA-like protein is usually referred to as TatB. The correct folding and/or incorporation of co-factors are requirements for translocation, and the known quality control mechanisms are examined in this review. A number of examples of crosstalk between the Tat system and other protein transport systems, such as the Sec–YidC translocon and signal peptidases or sheddases are also discussed. Further, an overview of specific Gram-positive bacterial Tat systems found in monoderm and diderm species is detailed. Altogether, this review highlights the unique features of Gram-positive bacterial Tat systems and pinpoints key questions that remain to be addressed in future research. This article is part of a Special Issue entitled: Protein trafficking and secretion in bacteria. Guest Editors: Anastassios Economou and Ross Dalbey. 相似文献
756.