全文获取类型
收费全文 | 349篇 |
免费 | 31篇 |
出版年
2023年 | 4篇 |
2022年 | 4篇 |
2021年 | 24篇 |
2020年 | 13篇 |
2019年 | 13篇 |
2018年 | 12篇 |
2017年 | 17篇 |
2016年 | 18篇 |
2015年 | 26篇 |
2014年 | 19篇 |
2013年 | 28篇 |
2012年 | 41篇 |
2011年 | 40篇 |
2010年 | 21篇 |
2009年 | 13篇 |
2008年 | 18篇 |
2007年 | 7篇 |
2006年 | 9篇 |
2005年 | 12篇 |
2004年 | 7篇 |
2003年 | 7篇 |
2002年 | 4篇 |
2001年 | 1篇 |
2000年 | 2篇 |
1998年 | 3篇 |
1997年 | 3篇 |
1996年 | 1篇 |
1995年 | 2篇 |
1993年 | 2篇 |
1990年 | 2篇 |
1986年 | 1篇 |
1985年 | 2篇 |
1981年 | 1篇 |
1969年 | 2篇 |
1937年 | 1篇 |
排序方式: 共有380条查询结果,搜索用时 218 毫秒
71.
Éva E. Plagányi Richard McGarvey Caleb Gardner Nick Caputi Darren Dennis Simon de Lestang Klaas Hartmann Geoffrey Liggins Adrian Linnane E. Ingrid Brett Arlidge Bridget Green Cecilia Villanueva 《Reviews in Fish Biology and Fisheries》2018,28(1):57-87
Australia’s lobster fisheries are relatively small in volume (9500t) compared with global production (289,000t), but are the country’s most valuable in terms of both overall production and value of export (2014 Gross Value of Production of $610 million AUD). Further, they support commercial, recreational and indigenous fishers along most of the continent’s coastline. Here we review similarities and key differences between these lobster fisheries, based on biological characteristics, fishery data collection, assessment and management methods, and supply chain considerations. A diverse range of palinurid lobsters occur in Australia, but only three genera, distributed across eight different management jurisdictions, support significant fisheries. Catches of western rock lobster Panulirus cygnus dominate landings (61%), followed by southern rock lobster Jasus edwardsii, tropical lobster Panulirus ornatus and the eastern rock lobster Sagmariasus verreauxi. Large-scale environmental influences such as climate change are impacting on these fisheries in similar or different ways forcing new management and raising the need for greater resilience in current supply chains. Although these are separate fisheries, the integrated nature of the dominant Chinese export markets suggests potentially important economic and market-related interactions. Our overview highlights the critical role of continued monitoring of recruitment pulses, in combination with robust harvest strategies, to ensure that harvests respond adequately and fisheries achieve biological and economic sustainability. Approaches that also include socio-cultural considerations (triple bottom line) are important given many fisheries include indigenous Australians. Our integrated analysis of Australian lobster fisheries highlights differences and similarities with spiny lobster fisheries worldwide and lessons from opportunities, including adapting to new free trade agreements, enhancing the reputation of wild lobsters as a whole, sharing expertise, and better alignment of supply and demand. 相似文献
72.
An Integrated Experimental and Computational Approach for Characterizing the Kinetics and Mechanism of Triadimefon Racemization
下载免费PDF全文
![点击此处可从《Chirality》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Qianyi Cheng Quincy Teng Satori A. Marchitti Caleb M. Dillingham John F. Kenneke 《Chirality》2016,28(9):633-641
Enantiomers of chiral molecules commonly exhibit differing pharmacokinetics and toxicities, which can introduce significant uncertainty when evaluating biological and environmental fates and potential risks to humans and the environment. However, racemization (the irreversible transformation of one enantiomer into the racemic mixture) and enantiomerization (the reversible conversion of one enantiomer into the other) are poorly understood. To better understand these processes, we investigated the chiral fungicide, triadimefon, which undergoes racemization in soils, water, and organic solvents. Nuclear magnetic resonance (NMR) and gas chromatography / mass spectrometry (GC/MS) techniques were used to measure the rates of enantiomerization and racemization, deuterium isotope effects, and activation energies for triadimefon in H2O and D2O. From these results we were able to determine that: 1) the alpha‐carbonyl carbon of triadimefon is the reaction site; 2) cleavage of the C‐H (C‐D) bond is the rate‐determining step; 3) the reaction is base‐catalyzed; and 4) the reaction likely involves a symmetrical intermediate. The B3LYP/6–311 + G** level of theory was used to compute optimized geometries, harmonic vibrational frequencies, nature population analysis, and intrinsic reaction coordinates for triadimefon in water and three racemization pathways were hypothesized. This work provides an initial step in developing predictive, structure‐based models that are needed to identify compounds of concern that may undergo racemization. Chirality 28:633–641, 2016. © 2016 Wiley Periodicals, Inc. 相似文献
73.
74.
Korinna Kochinke Christiane Zweier Bonnie Nijhof Michaela Fenckova Pavel Cizek Frank Honti Shivakumar Keerthikumar Merel?A.W. Oortveld Tjitske Kleefstra Jamie?M. Kramer Caleb Webber Martijn?A. Huynen Annette Schenck 《American journal of human genetics》2016,98(1):149-164
Intellectual disability (ID) disorders are genetically and phenotypically extremely heterogeneous. Can this complexity be depicted in a comprehensive way as a means of facilitating the understanding of ID disorders and their underlying biology? We provide a curated database of 746 currently known genes, mutations in which cause ID (ID-associated genes [ID-AGs]), classified according to ID manifestation and associated clinical features. Using this integrated resource, we show that ID-AGs are substantially enriched with co-expression, protein-protein interactions, and specific biological functions. Systematic identification of highly enriched functional themes and phenotypes revealed typical phenotype combinations characterizing process-defined groups of ID disorders, such as chromatin-related disorders and deficiencies in DNA repair. Strikingly, phenotype classification efficiently breaks down ID-AGs into subsets with significantly elevated biological coherence and predictive power. Custom-made functional Drosophila datasets revealed further characteristic phenotypes among ID-AGs and specific clinical classes. Our study and resource provide systematic insights into the molecular and clinical landscape of ID disorders, represent a significant step toward overcoming current limitations in ID research, and prove the utility of systematic human and cross-species phenomics analyses in highly heterogeneous genetic disorders. 相似文献
75.
Lijiang Ma Yavuz Bayram Heather M. McLaughlin Megan T. Cho Alyson Krokosky Clesson E. Turner Kristin Lindstrom Caleb P. Bupp Katey Mayberry Weiyi Mu Joann Bodurtha Veronique Weinstein Neda Zadeh Wendy Alcaraz Zöe Powis Yunru Shao Daryl A. Scott Andrea M. Lewis Janson J. White Shalani N. Jhangiani Elif Yilmaz Gulec Seema R. Lalani James R. Lupski Kyle Retterer Rhonda E. Schnur Ingrid M. Wentzensen Sherri Bale Wendy K. Chung 《Human genetics》2016,135(12):1399-1409
76.
Same school,different conduct: rates of multiple paternity vary within a mixed‐species breeding school of semi‐pelagic cichlid fish (Cyprichromis spp.)
下载免费PDF全文
![点击此处可从《Ecology and evolution》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Caleb Anderson Alexandra Werdenig Stephan Koblmüller Kristina M. Sefc 《Ecology and evolution》2016,6(1):37-45
Mating system variability is known to exist between and within species, often due to environmental influences. An open question is whether, vice versa, similar environmental conditions entail congruent mating behavior, for example in terms of multiple paternity, in species or populations sharing largely comparable breeding modes. This study employed microsatellite markers to investigate the incidence of multiple paternity in Cyprichromis coloratus and Cyprichromis leptosoma, two sympatric, closely related, mouthbrooding Lake Tanganyika cichlids with similar ecological and behavioral characteristics including the formation of open‐water schools. Mouthbrooding females of both species were collected from the same mixed‐species breeding school at the same time, minimizing environmental variation during courtship and mating. In C. coloratus, four of 12 broods had more than one sire, with a mean of 1.33 reconstructed sires per brood. C. leptosoma exhibited multiple paternity in 18 of 22 broods, with a mean of 2.59 or 2.86 reconstructed sires per brood according to the programs gerud and colony , respectively. In addition, two broods were found to contain offspring transplanted from another brood. There was no significant difference in brood size between species, but mean sire number did differ significantly. Hence, substantial similarity in reproductive behavior along with shared environmental conditions during courtship and spawning did not lead to equal rates of polyandry or sneaking in the two species. 相似文献
77.
Caleb E. Finch Jeffrey R. Foster Alfred E. Mirsky 《The Journal of general physiology》1969,54(6):690-712
The inability to maintain body temperature and a selective pattern of changes in the regulation of cell activities were revealed by briefly exposing ageing C57B1/6J male mice to cold (10°C). The induction of liver tyrosine aminotransferase (TAT) during exposure to cold (a gene-dependent process) was markedly delayed in senescent mice (26 months old) as compared with younger mice (3–16 months old); after the delay, the rate of increase of TAT was similar to that prevailing in younger mice. Direct challenge of the liver with injections of corticosterone or insulin elicited the induction of TAT on an identical time course in young and senescent mice. These experiments provide an example of an age change in a gene-dependent cell process (the delayed induction of TAT in senescent mice during exposure to cold) which is not due to a change in the potential of the genome for responding when exogenous stimulae are supplied (injection of hormones). In contrast to the age-related change in liver cell activities, no significant changes were found in the secretion of corticosterone during exposure to cold. Although the seat of these selective age-related changes in the regulation of cell activities remains unclear, it is argued that generalized damage to the genome of cells throughout the body is not involved. The results of this and other studies showing the selective effect of age on cell activities are considered in terms of the concept that many cellular age changes represent the response of cells to primary age-related changes in humoral factors in the internal environment of the body. 相似文献
78.
Exotic ecosystem engineers induce structural and qualitative habitat changes in invaded landscapes, yet studies rarely examine the effects of both of these changes on native taxa. We used a factorial experiment in natural, predator‐containing environments to determine whether performance of amphibian larvae was affected by predators and/or changes in habitat structure or chemistry associated with the invasive shrub Lonicera maackii. Invertebrate predators significantly reduced survival of American toad Anaxyrus americanus larvae, whereas tadpole development was accelerated in pools inoculated with the chemical signature of L. maackii. The significant effect of L. maackii chemistry on A. americanus larvae suggests that invasive species may have non‐intuitive effects even on native taxa with which they share no trophic connection, and may represent cryptic components of the multiple, interactive drivers of biodiversity change. 相似文献
79.
80.
Claudia C. Lardizábal Dilenia E. Martínez Lesbia E. Zamora Caleb D. McMahan Wilfredo A. Matamoros 《Journal of fish biology》2020,97(4):1273-1275
Here we report the first record of the Mayan cichlid, Mayaheros urophthalmus, occurring on an offshore island 70 km from the mainland, the most distant record from the mainland to date. Specimens were collected during several ichthyological surveys on the island of Guanaja, Honduras in November 2019. Mayan cichlids are euryhaline fishes that perform very well in fresh, brackish and marine waters. It has been hypothesized that their high tolerance to salinity and potential of using costal waterways has facilitated the colonization and expansion of M. urophthalmus. 相似文献