Wetland environment and habitat loss increase the rate of biodiversity decline and affect our ecosystems. Yancheng National Nature Reserve (YNNR) is a protected area dedicated to endangered migratory bird species to overwinter. However, it currently has a record low influx of migrating birds and might therefore be losing its founding purpose. We used remote sensing technology to assess and quantify the impacts and effects of invasive halophytes Spartina alterniflora in the habitat loss and shrinkage of endangered bird wintering habitat from 2003 to 2018. We also attempted to ascertain the causes and triggers of avian population decline and its relationship with habitat loss, as these phenomena threaten and endanger species both locally and globally. Our study shows how YNNR has lost about 80% of migratory bird habitat to invasive S. alterniflora and Phragmites australis, a native halophyte plant in the reserve. Furthermore, shoreline erosion triggered the retraction of S. alterniflora and its backward growth toward Suaeda Salsa, the preferred foraging habitat for migratory birds in the zone, which is a possible cause of their decline. 相似文献
Cellular and Molecular Neurobiology - Valproate (VPA), a widely-used antiepileptic drug, is a selective inhibitor of histone deacetylase (HDAC) that play important roles in epigenetic regulation.... 相似文献
Intracerebral hemorrhage (ICH) causes long term neurological abnormality or death. Oxidative stress is closely involved in ICH mediated brain damage. Steroid receptor cofactor 3 (SRC-3), a p160 family member, is widely expressed in the brain and regulates transactivation of Nrf2, a key component of antioxidant response. Our study aims to test if SRC-3 is implicated in ICH mediated brain injury. We first examined levels of SRC-3 and oxidative stress in the brain of mice following ICH and analyzed their correlation. Then ICH was induced in wild type (WT) and SRC-3 knock out mice and how SRC-3 deletion affected ICH induced brain damage, oxidative stress and behavioral outcome was assessed. We found that SRC-3 mRNA and protein expression levels were reduced gradually after ICH induction in WT mice along with an increase in oxidative stress levels. Correlation analysis revealed that SRC-3 mRNA levels negatively correlated with oxidative stress. Deletion of SRC-3 further increased ICH induced brain edema, neurological deficit score and oxidative stress and exacerbated ICH induced behavioral abnormality including motor dysfunction and cognitive impairment. Our findings suggest that SRC-3 is involved in ICH induced brain injury, probably through modulation of oxidative stress.
Neurochemical Research - Gut microbiota is closely related to the Parkinson’s disease (PD) pathogenesis. Additionally, aggregation of α-synuclein (α-syn) is central to PD... 相似文献