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71.
Summary Activities of the lactate dehydrogenase within the periportal zone and within the perivenous zone in the first layer of hepatocytes adjacent to terminal hepatic venules and the remainder of the perivenous parenchyma of the liver acinus were measured using a Lowry technique during a full 24-h cycle (08.00-08.00) in untreated adult male Wistar rats kept under 12 h of light and 12 h of darkness, scotophase 18.25-06.25. In all three regions studied a broad first maximum was recorded between 10.00 and 22.00 with the peak value at 16.00 and a high and narrow peak at 24.00. Zonal and intrazonal heterogeneity of the lactate dehydrogenase were retained during the full day and night cycle. The regions displayed individual dynamic changes in enzyme activity.Supported by the Deutsche Forschungsgemeinschaft (Hi 318/21) 相似文献
72.
Sixteen Choisya ternata strains of same genotypic origin were examined for their capacities to biotransform ellipticine. Four strains were able to convert the drug into 5-formylellipticine with good yields. The reaction occurred only in agar medium and was different from ellipticine bioconversion by microorganisms or mammals. 相似文献
73.
G. Röhrborn V. Sezer I. -D. Adler A. Schmaltz I. H. Pawlowitzki Ch. Nautsch 《Human genetics》1978,42(1):55-58
Summary Mutagenic damages in female germ, cells of mice have been tested with the dominant, lethal assay and the cytogenetic analysis of unfertilized M II-oocytes. Concluding one can say that from the experimental data presented here do not show any mutagenic effect of INH on oogenesis of different strains of mice can be stated. 相似文献
74.
In order to determine the significance of the C-6 carboxyl group for the biological activity gibberellin A3, 6-epigibberellin A3, 7-norgibberellin A3, 6-methyl-7-norgibberellin A3, and 7-homogibberellin A3 were studied using dwarf pea, dwarf maize, dwarf rice, dwarf barley and -amylase bioassays. All gibberellin A3(GA3)derivatives tested were considerably less active than GA3. In all biossays, 6-epi-GA3 showed a low activity of the same order, whereas 6-methyl-7-nor-GA3 was inactive. Surprisingly, 7-nor-GA3 had some activity in the dwarf rice (root application), dwarf barley, and -amylase bioassay, in contrary to its low potency in the dwarf pea, dwarf maize, and dwarf rice (micro drop) bioassay. 7-Homo-GA3 was primarily active in the dwarf maize, dwarf barley and dwarf rice bioassay. It also caused antigibberellin effects in dwarf rice. The results demonstrate that the C-6 carboxyl group is not absolutely essential for biological activity of gibberellins. The different activities of 7-nor-GA3 observed in the various test systems may indicate that the C-6 carboxyl group is a structural requirement more for uptake and/or transport processes than for receptor affinity.Abbreviation GA3
gibberellic acid 相似文献
75.
Summary A saturator of small dimensions is described. Moist air with dewpoint temperatures ranging from 2°C to 30°C with a long-term stability of ±0.05°C and a maximum output of 400 1/h can be attained.Special attention is paid to the calibration procedure and to the effect of the reduction of dewpoint temperature of moist air flowing through a tube. 相似文献
76.
Summary One hundred and sixty-seven blood donors, 26 families with 72 offspring and 12 motherchild couples were studied for the phosphoglycolate phosphatase polymorphism. In hemolysates, the isozymes are stable for at least five weeks. The distribution of observed phenotypes in the population study did pot diverge from the expected values according to Hardy-Weinberg law. In the family study, the formal genetic model of three alleles—PGP
1, PGP
2 and PGP
3 at one autosomal locus-could be confirmed. Among 33 individuals from a Mongoloid population PGP 1 was observed in 100%. This observation lead us to the conclusion, based also on recent data in Negroid populations (Barker and Hopkinson 1978), that phosphoglycolate phosphatase may be a more recent polymorphism of Caucasoid populations. Linkage studies with the hp locus an chromosome 16 resulted in 19 meiotic divisions of 4 informative families in a lod score peak of 0.23 at =0.25 being inconclusive. The inclusion of the PGP system in paternity testing is also discussed. 相似文献
77.
Steady state patterns of currents flowing extracellularly in the receptor layer of the frog retina are used to work out an electrical model of vertebrate rods. The model can be thought of as a linear network consisting of resitances and current sources. The model predicts the axial spread of currents along the outside of the receptors. In addition, it predicts membrane voltages in light and darkness. If the dark-adapted receptors are assumed to have a uniform membrane with a specific resistance of 500 ·cm2, a single rod gives rise to an extracellular dark current of about 200 pa. 相似文献
78.
G. C. Gorman Y. J. Kim Ch. E. Taylor 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》1977,49(1):9-14
Summary Whiptail lizards (Cnemidophoms tigris) were collected from fenced irradiated, fenced control, and unfenced areas near Mercury Nevada. No changes in allele frequencies at 26 allozyme loci could be ascribed to irradiation or fencing. This species is the most polymorphic and heterozygous lizard so far examined. — Heterozygosity estimates derived from electrophoretic studies on 20 additional species of lizards are compared with Cnemidophorus. A general trend seems to emerge. Fossorial lizards have uniformly low levels of heterozygosity (ca. 1 %). Territorial sit and wait predators are intermediate (ca. 5%). Highly vagile apparently nonterritorial lizards are the most heterozygous (ca. 10%). Assuming that this trend does not reflect some of sampling error, two current, non-mutually exclusive hypotheses explain the observed situation: (1) the niche width variation hypothesis predicts, higher variability in populations where individuals are exposed to largescale environmental heterogeneity; and (2) the population size hypothesis predicts that, all other things being equal, vagility would tend to increase the effective population size by reducing inbreeding, which would promote higher levels of genetic variation. 相似文献
79.
Orlin Ch. Ivanov 《Journal of molecular evolution》1978,12(1):1-10
Summary An analysis is made of the applicability of the recently published profiles of relationship method for establishing evolutionary relatedness among proteins by using the distantly related proinsulin and neurotoxin protein se-quences as a test object. The method is based on a simultaneous group analysis of both the frequency of acceptance of mutations and their genetic code inter-changeability. Regularities in the patterns of the profiles, which reflect decreased similarity with the passage of time, are established for typical cases of closely related, distantly related and unrelated proteins. This makes it possible to distinguish distantly related from unrelated proteins without extensive statistical randomization procedures. New evidence is stated in favour of a previously suggested definition of interchangeability which does not consider the third base in the codon. The applicability of the profiles of relationship method is examined on the distant relationship between proinsulin and the snake and scorpion neurotoxins which has been established previously by means of conventional approaches. 相似文献
80.
Summary On a soil rich in CaCO3 in a semiaride climate in Algeria a hard soil layer, impermeable for plant roots, was formed in a depth of 20–40 cm after
farmyard manure application and irrigation.
To find the reason soil samples of this field were taken and leaching experiments were carried out in the laboratory, with
the result that much more Caions and HCO3-ions were leached out of the soils with farmyard manure application than from the soils without manure.
Probably the high amount of CO2, being liberated by the organic matter, and the irrigation water dissolved the CaCO3 in the soil, and the formed Ca- and HCO3-ions followed the movement of water in the soil. Where the Ca(HCO3)2 reached soil layers with a less amount of CO2, CaCO3 precipitated and formed the hard soil layer.
In order to avoid the formation of such calcareous crusts on irrigated, limy soils in a dry climate it is recommended to fertilize
rather often small quantities instead of rarely big quantities of farmyard manure. 相似文献