Le syndrome de Klinefelter à 20 ans: A propos de 426 observations

Based on a personal series of 426 consecutive observations, the authors look into the different clinical, psychological and biological aspects of Klinefelter' syndrome in subjects aged around twenty. They emphasize the misleading forms and the need to get the karyotype in all patients presenting with any genitalia or pubertal development abnormalities. Testosterone treatment must be given as early as possible around the age of 11–12 years. This therapy is always beneficial in all aspects including the improvement of the psychosocial adjustment.     

THE PROBLEM OF THE EVALUATION OF ROTENONE-CONTAINING PLANTS

A study has been made of the rotations of the resins from three types of derris root, and of a fraction rich in toxicarol separated from two of them. No strictly quantitative relationship between their rotations and their toxicities to Aphis rumicis has been found. The addition of caustic potash in methyl alcohol to the benzene solutions of the resins induces a characteristic change from laevo- to dextro-rotation in the samples rich in toxicarol. The induced dextro-rotation then declines in value with time. This effect is shown by the "toxicarol" resin. The rate of the decline is accelerated by increasing the amount of methyl alcohol.
We are greatly indebted to the Copper Technical Bureau for gifts of the "Sumatra-type" root and of resins derived from this strain.
We wish to express our thanks to Mr C. Read for help during the course of this work.