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41.
Halofuginone‐induced autophagy suppresses the migration and invasion of MCF‐7 cells via regulation of STMN1 and p53
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Anne Bolin 《American anthropologist》2002,104(4):1242-1244
Bike Lust: Harleys, Women and American Society. Barbara Joans. Madison: University of Wisconsin Press, 2001. 264 pp. 相似文献
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W. H. Raskind Tamara Bolin John Wolff John Fink Mark Matsushita Michael Litt Hillary Lipe Thomas D. Bird 《Human genetics》1998,102(1):93-97
Paroxysmal dystonic choreoathetosis (PDC) is a rare neurological disorder characterized by episodes of involuntary movement,
involving the extremities and face, which may occur spontaneously or be precipitated by caffeine, alcohol, anxiety, and fatigue.
PDC is transmitted as an autosomal dominant trait with incomplete penetrance. A gene implicated in this paroxysmal disorder
has been mapped to a 10–15 cM region on chromosome 2q31–36 in two families. We describe a third family with PDC. Two-point
linkage analyses with markers linked to the candidate PDC locus were performed. A maximum two-point LOD score of 4.20 at a
recombination fraction of zero was obtained for marker D2S120, confirming linkage to the distal portion of chromosome 2q.
The anion exchanger gene, SLC2C, maps to this region, but the family was poorly informative for polymorphic markers within
and flanking this candidate gene. Haplotype analysis revealed a critical recombination event that confines the PDC gene to
a 5-cM region bounded by the markers D2S164 and D2S377. We compared the haplotype in our family with that in another chromosome
2-linked PDC family, but did not detect a region of shared genotypes. However, identifying a third family whose disease maps
to the same region and narrowing the critical region will facilitate identification of the 2q-linked PDC gene.
Received: 10 June 1997 / Accepted: 17 September 1997 相似文献
45.
Host specific variation in photosynthesis of an obligate xylem‐tapping mistletoe Dendrophthoe curvata in a Bornean heath forest
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Quang‐Vuong Le Kushan U. Tennakoon Faizah Metali Linda B. L. Lim Jay F. Bolin 《Nordic Journal of Botany》2016,34(2):235-243
Most mistletoe–host ecophysiological studies have paid attention to the influence of parasites on host performance. This paper explored the impact of varying hosts on the photosynthesis of a single mistletoe species. Here, we studied an obligate xylem‐tapping tropical mistletoe (Dendrophthoe curvata (Blume) Miquel) parasitizing four different hosts (Acacia auriculiformis A. Cunn. Ex Benth, Andira inermis (W. Wright) DC., Mangifera indica L. and Vitex pinnata L.) in a homo geneous tropical heath forest patch in Brunei Darussalam. We compared photosynthetic capacity and photosynthesis‐related characteristics of the mistletoe on four different hosts to evaluate the overall impact of hosts on the parasite. Results showed that the mistletoe–host patterns of CO2 assimilation rates, transpiration rates and water use efficiency varied significantly based on the host. In the D. curvata–Vitex pinnata association, the mistletoe exhibited significantly lower CO2 assimilation rates but showed no significant variations in transpiration rates and water use efficiency when compared to the host. In D. curvata–Andira inermis and D. curvata–Mangifera indica associations, the mistletoe showed significantly higher photosynthetic rates than the hosts, whereas in the D. curvata–Acacia auriculiformis association, there was no significant difference in photosynthetic rates between the counterparts. Host specificity also significantly influenced some mistletoe photosynthetic parameters such as light saturated photosynthesis, specific leaf area, leaf chlorophyll content, CO2 assimilation rates, stomatal conductance, transpiration rates and water use efficiency. Different tree hosts intrinsically offer different resources to their obligate mistletoe parasites based on their physiology and environmental parameters. We argue that host‐specific responses have driven these intra‐specific variations in mistletoe physiology. This study provides background for future investigation on potential host‐regulated mechanisms that drive functional changes in host‐dependent mistletoes. 相似文献
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