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991.
开花期是水稻最重要的农艺性状之一,水稻的花期决定着水稻的地区适应性和最终产量。人工选择使水稻从短日照向长日照、低纬度向高纬度扩张,因此水稻已逐渐进化出适应长日照条件下的开花调控机制。目前,虽然鉴定了一些影响水稻长日照的开花基因如SDG724、RFT1、EHD4、DTH2,但是挖掘水稻长日照开花基因还十分有限。本研究通过筛选水稻突变体库,获得一批在长日照下花期有显著差异的突变体材料,其中一份突变体lfm1(late-flowering mutant1),在长日照条件下开花延迟,在短日照条件下开花时间正常。通过图位克隆,将Lfm1基因初定位至第8染色体端粒附近。进一步的精细定位将Lfm1基因定位于分子标记8-0.269和与8-0.283之间,范围为12 kb,该区域包括3个候选基因。经测序分析发现,在突变体lfm1中,LOC_Os08g01420基因的第六外显子2800处缺失9个碱基,突变体lfm1等位于已报道的突变体ehd3。在适度(中日照条件下,~12 h/12 h)的光照条件下,突变体lfm1表现为穗粒数增多,生育期略延长,具有应用于生产的潜力。Lfm1基因的克隆为培育适应不同生态区域的水稻材料提供了重要的基因资源。  相似文献   
992.
Zheng  Yang  Zhang  Qing  Ali  Ashaq  Li  Ke  Shao  Nan  Zhou  Xiaoli  Ye  Zhiqin  Chen  Xiaomin  Cao  Shanshan  Cui  Jing  Zhou  Juan  Wang  Dianbing  Hou  Baidong  Li  Min  Cui  Mengmeng  Deng  Lihua  Sun  Xinyi  Zhang  Qian  Yang  Qinfang  li  Yong  Wang  Hui  Lei  Yake  Yu  Bo  Cheng  Yegang  Tong  Xiaolin  Men  Dong  Zhang  Xian-En 《中国病毒学》2021,36(5):869-878
Virologica Sinica - Understanding the persistence of antibody in convalescent COVID-19 patients may help to answer the current major concerns such as the risk of reinfection, the protection period...  相似文献   
993.
African swine fever virus(ASFV), as a member of the large DNA viruses, may regulate autophagy and apoptosis by inhibiting programmed cell death. However, the function of ASFV proteins has not been fully elucidated, especially the role of autophagy in ASFV infection. One of three Pyrroline-5-carboxylate reductases(PYCR), is primarily involved in conversion of glutamate to proline. Previous studies have shown that depletion of PYCR2 was related to the induction of autophagy. In the present study, we found for the first time that ASFV E199 L protein induced a complete autophagy process in Vero and HEK-293 T cells. Through co-immunoprecipitation coupled with mass spectrometry(CoIP-MS)analysis, we firstly identified that E199 L interact with PYCR2 in vitro. Importantly, our work provides evidence that E199 L down-regulated the expression of PYCR2, resulting in autophagy activation. Overall, our results demonstrate that ASFV E199 L protein induces complete autophagy through interaction with PYCR2 and down-regulate the expression level of PYCR2, which provide a valuable reference for the role of autophagy during ASFV infection and contribute to the functional clues of PYCR2.  相似文献   
994.
Zhao  Yu  Ma  Chen  Yang  Jie  Zou  Xiufen  Pan  Zishu 《中国病毒学》2021,36(6):1327-1340
Virologica Sinica - Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infections in children. Inactivated RSV vaccine was developed in the late 1960’s, but the...  相似文献   
995.
Yu  Du  Zhao  Yundi  Pan  Junhui  Yang  Xingmiao  Liang  Zhenjie  Xie  Shengda  Cao  Ruibing 《中国病毒学》2021,36(6):1443-1455
Virologica Sinica - The Japanese encephalitis serogroup of the neurogenic Flavivirus has a specific feature that expresses a non-structural protein NS1′ produced through a programmed -1...  相似文献   
996.
Zhu  Yun  Xu  Baoping  Li  Changchong  Chen  Zhimin  Cao  Ling  Fu  Zhou  Shang  Yunxiao  Chen  Aihuan  Deng  Li  Bao  Yixiao  Sun  Yun  Ning  Limin  Yu  Shuilian  Gu  Fang  Liu  Chunyan  Yin  Ju  Shen  Adong  Xie  Zhengde  Shen  Kunling 《中国病毒学》2021,36(6):1543-1553
Virologica Sinica - Community-acquired pneumonia (CAP) is one of the leading causes of morbidity and mortality in children worldwide. In this study, we aimed to describe the aetiology of viral...  相似文献   
997.
Zhang  Xinheng  Chen  Tong  Chen  Sheng  Nie  Yu  Xie  Zi  Feng  Keyu  Zhang  Huanmin  Xie  Qingmei 《中国病毒学》2021,36(6):1431-1442
Virologica Sinica - Infectious bronchitis (IB) is a highly contagious avian disease caused by infection with infectious bronchitis virus (IBV), which seriously affects the development of the global...  相似文献   
998.
Yu  Huan  Ou-Yang  Yi-Yi  Yang  Chang-Jin  Li  Ni  Nakai  Madoka  Huang  Guo-Hua 《中国病毒学》2021,36(5):1036-1051
Virologica Sinica - 3h-31 of Heliothis virescens ascovirus 3h (HvAV-3h) is a highly conserved gene of ascoviruses. As an early gene of HvAV-3h, 3h-31 codes for a non-structural protein (3H-31) of...  相似文献   
999.
Carex sect. Confertiflorae s.l. is a medium-sized species group (ca. 40 species) with its center of diversity in E Asia (China and Japan). According to morphological traits, the section has been proposed to split into two sections (sects. Confertiflorae sensu Ohwi and Molliculae Ohwi) up to five different ones (sects. Confertiflorae s.s., Molliculae, Dispalatae Ohwi, Ischnostachyae Ohwi, and Alliiformes Akiyama). Recent phylogenetic reconstructions showed Confertiflorae s.l. not to be monophyletic, as species traditionally considered part of it were found to belong to other clades, whereas species traditionally ascribed to other sections were nested within it. In this study, we investigated the phylogenetic structure, morphological affinities, and biogeographic history of sect. Confertiflorae s.l. We employed a taxon-based approach to explore the morphological affinities of the species considered in sect. Confertiflorae and compared the micromorphology of the nutlets of almost all the taxa using SEM. We included 40 samples representing 31 species/subspecies of sect. Confertiflorae s.l. and used two nuclear (ETS and ITS) and three plastid (trnL-F, matK, and rpl32-trnL UAG) molecular markers to reconstruct the phylogeny of the group. The phylogenetic analyses confirmed the polyphyly of sect. Confertiflorae s.l., whose representatives were found within five distinct clades. From these, two clades, sect. Confertiflorae and sect. Molliculae, were found to be closely related and contained the majority of the species. The composition of the two clades agreed with the morphological structure of the group, and we confirmed an exclusive combination of features (namely color of basal sheaths, presence of bract sheath, peduncle of lowest spike, inflorescence sex distribution, shape of pistillate glume apex, and color and veins of utricle, among others) characterizing each of the two clades. The origin of the two clades was found to be in the early Pliocene; however, the majority of the diversification events within each clade took place during the Pleistocene. This illustrates that although Asia has been regarded as having little potential ecological space for Carex to diversify due to its climate stability, groups of sedges sub-endemic from that area may have a fairly recent origin related to glaciations. We proposed the rearrangement of sect. Confertiflorae as previously conceived as three independent sections: the monotypic Alliiformes, sect. Molliculae, and sect. Paludosae.  相似文献   
1000.
高血压(hypertension,high blood pressure)是动脉血压持续偏高的慢性疾病,是人类社会最为常见的慢性医学问题.80%以上的高血压患者了解他们自身的血压状况,其中70%以上的患者服用治疗高血压药物.然而,这些认识到自身高血压状况的人中,只有48%的患者的高血压得到了充分的控制.本文系统地阐述了高血压的类型、诊断标准及治疗或控制策略,以期提高公众对高血压的认知,有利于患者对高血压的控制和管理.  相似文献   
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