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11.
12.
Richard Biebl 《Protoplasma》1939,32(1):443-463
Ohne ZusammenfassungFür die Bereitstellung eines Arbeitsplatzes an der Staatlichen Biologischen Anstalt auf Helgoland und die freundliche Unterstützung, die ich dort erfahren habe, sage ich dem Direktor der Anstalt, Prof. Dr. Hagmeier sowie den Herren des Institutes meinen besten Dank.Herrn Univ.-Prof. Dr. V. Schiffner, Wien habe ich wiederum für die liebenswürdige Bestimmung einiger Versuchsalgen herzlich zu danken. 相似文献
13.
Ohne ZusammenfassungHerrn Professor Dr. Karl Höfler zu seinem 70. Geburtstag in Dankbarkeit gewidmet.This investigation was supported by the International Atomic Energy Agency. 相似文献
14.
Microbial production of 1,3-propanediol 总被引:79,自引:2,他引:77
H. Biebl K. Menzel A.-P. Zeng W.-D. Deckwer 《Applied microbiology and biotechnology》1999,52(3):289-297
1,3-Propanediol (1,3-PD) production by fermentation of glycerol was described in 1881 but little attention was paid to this
microbial route for over a century. Glycerol conversion to 1,3-PD can be carried out by Clostridia as well as Enterobacteriaceae.
The main intermediate of the oxidative pathway is pyruvate, the further utilization of which produces CO2, H2, acetate, butyrate, ethanol, butanol and 2,3-butanediol. In addition, lactate and succinate are generated. The yield of 1,3-PD
per glycerol is determined by the availability of NADH2, which is mainly affected by the product distribution (of the oxidative pathway) and depends first of all on the microorganism
used but also on the process conditions (type of fermentation, substrate excess, various inhibitions). In the past decade,
research to produce 1,3-PD microbially was considerably expanded as the diol can be used for various polycondensates. In particular,
polyesters with useful properties can be manufactured. A prerequisite for making a “green” polyester is a more cost-effective
production of 1,3-PD, which, in practical terms, can only be achieved by using an alternative substrate, such as glucose instead
of glycerol. Therefore, great efforts are now being made to combine the pathway from glucose to glycerol successfully with
the bacterial route from glycerol to 1,3-PD. Thus, 1,3-PD may become the first bulk chemical produced by a genetically engineered
microorganism.
Received: 12 January 1999 / Received revision: 9 March 1999 / Accepted: 14 March 1999 相似文献
15.
Ohne Zusammenfassung 相似文献
16.
Richard Biebl 《Protoplasma》1935,24(1):225-257
Ohne Zusammenfassung 相似文献
17.
Richard Biebl 《Protoplasma》1938,30(1):570-576
18.
Richard Biebl 《Protoplasma》1942,37(1):1-24
Ohne Zusammenfassung 相似文献
19.
Thomas Homann Carmen Tag Hanno Biebl Wolf-Dieter Deckwer Bernhard Schink 《Applied microbiology and biotechnology》1990,33(2):121-126
Summary Glycerol-fermenting anaerobes were enriched with glycerol at low and high concentrations in order to obtain strains that produce 1,3-propanediol. Six isolates were selected for more detailed characterization; four of them were identified as Citrobacter freundii, one as Klebsiella oxytoca and one as K. pneumoniae. The Citrobacter strains formed 1.3-propanediol and acetate and almost no by-products, while the Klebsiella strains produced varying amounts of ethanol in addition and accordingly less 1,3-propanediol. Enterobacterial strains of the genera Enterobacter, Klebsiella, and Citrobacter from culture collections showed similar product patterns except for one group which formed limited amounts of ethanol, but no propanediol. Seven strains were grown in pH-controlled batch cultures to determine the parameters necessary to evaluate their capacity for 1,3-propanediol production. K. pneumoniae DSM 2026 exhibited the highest final concentration (61 g/l) and the best productivity (1.7 g/l h) whereas C. freundii Zu and K2 achieved only 35 g/l and 1.4 g/l h, respectively. The Citrobacter strains on the other hand gave somewhat better yields which were very close to the theoretical optimum of 65 mol %.
Offprint requests to: H. Biebl 相似文献
20.
Richard Biebl 《Protoplasma》1941,36(1):491-513
Ohne Zusammenfassung 相似文献