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161.
Roy Amit Bhattacharyya Soma Sengupta Subhabrata Ghosh Anil Kumar 《World journal of microbiology & biotechnology》2001,17(7):727-729
Biochemical characterization of a trehalase, detected in the mid-exponential growth phase of Candida utilis NCIM Y500, has indicated that it was a neutral trehalase and possibly the only trehalase present in this strain. Unlike Saccharomyces cerevisiae and other C. utilis strains, this strain without acid trehalase grew quite well in minimal or complete medium containing trehalose as the sole source of carbon. Both these observations were contradictory to the findings reported for acid trehalase mutants of S. cerevisiae and C. utilis. The trehalase system of the strain is suggested to be similar to that of fungi. 相似文献
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Summary The effect of different concentrations of CO2 on the germination of conidiospores of Aspergillus niger A 5 has been studied using Pardee's buffer mixtures which maintain constant CO2 tensions. The beneficial effect of CO2 on germination is maximum at 0.5% CO2 concentration, when 70–90% of the spores germinate within 6 hours, whereas in controls with air containing 0.03% CO2 there is only 15–20% germination at 6 hours. At higher CO2 concentrations this beneficial effect of CO2 on germination diminishes and at 3% there is a complete inhibition of spore germination.The spore density and the ph of the medium have a noticeable effect on germination rates in presence of 0.5% CO2. The germination rates decrease at spore densities higher than 5 · 105/ml and at a ph of 6.8.Communication No. 431. 相似文献
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Bodhendu B. Gupta Anjan Bhattacharyya Santi R. Mitra Narayan Adityachaudhury 《Phytochemistry》1983,22(5):1306-1307
The pods of Milletia auriculata have yielded a new substance, 5,7-dihydroxy-6-methoxy-4′-O-prenyloxyisoflavone. 相似文献
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Meenu Narwal Deepak Kumar Tapan Kumar Mukherjee Rajasri Bhattacharyya Dibyajyoti Banerjee 《Molecular biology reports》2018,45(6):1647-1652
Human serum albumin (HSA) is a major plasma protein and binding of drugs with this plasma protein has a great importance. It possess esterase activity which can cleave the drugs containing ester bond and thus, can regulate the effect of drugs. Till date no systematic study has been done to analyse binding of such drugs and to compare the results with the drugs which do not have ester bond. Therefore, in the present study two different categories—ester and non-ester drugs have been considered to analyse their interaction with HSA at two principle drug binding sites using molecular modelling tools. It is observed that the drugs irrespective of ester or non-ester nature prefer either Sudlow site I or II by hydrogen bond and hydrophobic interactions. The information obtained from the study can assist to study pharmacokinetics of the drugs and that in turn will help in noval drug discoveries. 相似文献
170.
Mokhtarul Haque Rosy Sarmah Dhruba K. Bhattacharyya 《Journal of Genetic Engineering and Biotechnology》2018,16(1):227-238
Detection of protein complexes by analyzing and understanding PPI networks is an important task and critical to all aspects of cell biology. We present a technique called PROtein COmplex DEtection based on common neighborhood (PROCODE) that considers the inherent organization of protein complexes as well as the regions with heavy interactions in PPI networks to detect protein complexes. Initially, the core of the protein complexes is detected based on the neighborhood of PPI network. Then a merging strategy based on density is used to attach proteins and protein complexes to the core-protein complexes to form biologically meaningful structures. The predicted protein complexes of PROCODE was evaluated and analyzed using four PPI network datasets out of which three were from budding yeast and one from human. Our proposed technique is compared with some of the existing techniques using standard benchmark complexes and PROCODE was found to match very well with actual protein complexes in the benchmark data. The detected complexes were at par with existing biological evidence and knowledge. 相似文献