Ueber die Giftigkeit einiger Lebermoose

Ohne Zusammenfassung     

The influence of the environment (natural and experimental) on the composition of the exine of allergenic pollen with respect to the deposition of pollutant mineral particles

Pollen material of the two anemophilous plants of known allergic significance Dactylis glomerata (Poaceae) and Betula verrucosa (Betulaceae) was collected at several places (in Sweden and France) and exposed to natural or experimental conditions. This material was analyzed with Electron Probe X Microanalysis (EPMA) (System ORTEC 5000) attached to a Scanning Electron Microscope (Jeol JMS 35), or with EDAX, a 10000 X-Ray Analyser, Link System, connected to a SEM-microscope (Jeol JSM 820).

It is clear that the environment has an effect on such a co-inductor or adjuvant of allergenicity as K. The possible presence of pollutant inorganic (mineral) particles on the pollen grain surface may play a role in the allergenic activity. Pollen, consequently, may be used as sensitive biological indicators of atmospheric pollution.     

Author index to volume 154

Horseradish peroxidase-catalyzed N-demethylation of aminopyrine and dimethylaniline results in generation of free radical intermediates which can interact with glutathione (GSH) to form a glutathione radical. This can either dimerize to yield glutathione disulfide or react with O₂ to form oxygenated products of glutathione. Ethylmorphine is not a substrate in the peroxidase-mediated reaction, and free radical intermediates which react with GSH, are not formed from aminopyrine and dimethylaniline when the horseradish peroxidase/H₂O₂ system is replaced by liver microsomes and NADPH. Therefore, it appears unlikely that formation of free radical intermediates can be responsible for the depletion of GSH observed during N-demethylation of several drugs in isolated liver cells.     

Microvascular anastomoses in irradiated vessels: a comparison between the Unilink system and sutures

A new mechanical device (the Unilink system) was compared to conventional suture anastomoses in irradiated microvessels. Twenty rabbits received a single radiation dose of 20 Gy from a 7-MeV electron source through an anterior neck field. One and 6 months following irradiation, the carotid arteries and facial veins were divided and anastomosed on one side with the Unilink system and on the other side with suture technique. At sacrifice 4 weeks postoperatively, all vessels were evaluated for patency and histologic changes associated with radiation and anastomotic trauma. Histology disclosed severe radiation changes. Also, intimal hyperplasia was consistently found at the anastomotic sites in the arteries, while it was totally absent in the venous anastomoses. Occlusive thrombosis was found in two arteries, one anastomosed with the Unilink system and one sutured. Two other arteries, one from each group, had subtotal occlusions at the anastomotic site. No occlusions occurred in any of the venous anastomoses. The overall patency in this study was 97.5 percent, with no difference between the two techniques.