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101.
Although the use of formant frequencies in nonhuman animal vocal communication systems has received considerable recent interest, only a few studies have examined the importance of these acoustic cues to body size during intra-sexual competition between males. Here we used playback experiments to present free-ranging male koalas with re-synthesised bellow vocalisations in which the formants were shifted to simulate either a large or a small adult male. We found that male looking responses did not differ according to the size variant condition played back. In contrast, male koalas produced longer bellows and spent more time bellowing when they were presented with playbacks simulating larger rivals. In addition, males were significantly slower to respond to this class of playback stimuli than they were to bellows simulating small males. Our results indicate that male koalas invest more effort into their vocal responses when they are presented with bellows that have lower formants indicative of larger rivals, but also show that males are slower to engage in vocal exchanges with larger males that represent more dangerous rivals. By demonstrating that male koalas use formants to assess rivals during the breeding season we have provided evidence that male-male competition constitutes an important selection pressure for broadcasting and attending to size-related formant information in this species. Further empirical studies should investigate the extent to which the use of formants during intra-sexual competition is widespread throughout mammals. 相似文献
102.
Istem Fer Anthony K. Gardella Alexey N. Shiklomanov Eleanor E. Campbell Elizabeth M. Cowdery Martin G. De Kauwe Ankur Desai Matthew J. Duveneck Joshua B. Fisher Katherine D. Haynes Forrest M. Hoffman Miriam R. Johnston Rob Kooper David S. LeBauer Joshua Mantooth William J. Parton Benjamin Poulter Tristan Quaife Ann Raiho Kevin Schaefer Shawn P. Serbin James Simkins Kevin R. Wilcox Toni Viskari Michael C. Dietze 《Global Change Biology》2021,27(1):13-26
In an era of rapid global change, our ability to understand and predict Earth's natural systems is lagging behind our ability to monitor and measure changes in the biosphere. Bottlenecks to informing models with observations have reduced our capacity to fully exploit the growing volume and variety of available data. Here, we take a critical look at the information infrastructure that connects ecosystem modeling and measurement efforts, and propose a roadmap to community cyberinfrastructure development that can reduce the divisions between empirical research and modeling and accelerate the pace of discovery. A new era of data‐model integration requires investment in accessible, scalable, and transparent tools that integrate the expertise of the whole community, including both modelers and empiricists. This roadmap focuses on five key opportunities for community tools: the underlying foundations of community cyberinfrastructure; data ingest; calibration of models to data; model‐data benchmarking; and data assimilation and ecological forecasting. This community‐driven approach is a key to meeting the pressing needs of science and society in the 21st century. 相似文献
103.
104.
Carrie V. Kappel Carlos M. Duarte Keith Brander Christopher J. Brown John F. Bruno Lauren Buckley Michael T. Burrows Benjamin S. Halpern Wolfgang Kiessling Pippa Moore John M. Pandolfi Camille Parmesan Elvira S. Poloczanska David S. Schoeman William J. Sydeman Anthony J. Richardson 《Global Ecology and Biogeography》2015,24(1):64-76
105.
Benjamin L. VaughanJr. Bryan G. Smith David L. Chopp 《Bulletin of mathematical biology》2010,72(5):1143-1165
In this paper, we study quorum sensing in Pseudomonas aeruginosa biofilms. Quorum sensing is a process where bacteria monitor their population density through the release of extra-cellular
signalling molecules. The presence of these molecules affects gene modulation leading to changes in behaviour such as the
release of virulence factors. Here, we use numerical methods to approximate a 2-D model of quorum sensing. It is observed
that the shape of the biofilm can have a profound effect on the onset of quorum sensing. This has serious repercussions for
experimental observations since biofilms of the same biomass but different shapes can produce quite different results. 相似文献
106.
Georg Neubauer Stefan Cecil Wolfram Giczi Benjamin Petric Patrick Preiner Jürg Fröhlich Martin Röösli 《Bioelectromagnetics》2010,31(7):535-545
The selection of an adequate exposure assessment approach is imperative for the quality of epidemiological studies. The use of personal exposimeters turned out to be a reasonable approach to determine exposure profiles, however, certain limitations regarding the absolute values delivered by the devices have to be considered. Apart from the limited dynamic range, it has to be taken into account that these devices give only an approximation of the exposure due to the influence of the body of the person carrying the exposimeter, the receiver characteristics of the exposimeter, as well as the dependence of the measured value on frequency band, channel, slot configuration, and communication traffic. In this study, the relationship between the field strength measured close to the human body at the location of the exposimeter and the exposure, that is, the field strength at the location of the human body without the human body present, is investigated by numerical means using the Visible Human model as an anatomical phantom. Two different scenarios were chosen: (1) For FM, GSM, and UMTS an urban outdoor scenario was examined that included a transmitting antenna mounted on the roof of one of four buildings at a street crossing, (2) For WLAN an indoor scenario was investigated. For GSM the average degree of underestimation by the exposimeter (relation of the average field levels at the location of the exposimeter to the field level averaged over the volume of the human body without the body present) was 0.76, and for UMTS 0.87; for FM no underestimation was found, the ratio was 1. In the case of WLAN the degree of underestimation was more pronounced, the ratio was 0.64. This study clearly suggests that a careful evaluation of correction factors for different scenarios is needed prior to the definition of the study protocol. It has to be noted that the reference scenario used in this study does not allow for final conclusions on general correction factors. Bioelectromagnetics 31:535–545, 2010. © 2010 Wiley‐Liss, Inc. 相似文献
107.
The study is a survey of the shape and carbohydrate histochemistry of the endothelial cells lining the conus arteriosus of 10 species of elasmobranchs and the bulbus arteriosus of 80 species of teleosts. Intensely PAS-positive cells that were often tall, were found in many teleosts and were typical of phylogenetically advanced species. They were not seen in any elasmobranch. Most of the teleosts with strongly PAS-positive cells were marine fish or euryhaline animals that were caught in freshwater. Beyond this, it is difficult to generalize on their life-style or habitat, for they included small fish, large fish, fast swimmers, bottom-living forms, deep-water fish, littoral species and Antarctic "bloodless" forms. It is likely that the PAS-positivity of the endothelial cells can be attributed to the moderately-dense granules revealed by E.M., but as yet the significance of these is unclear. 相似文献
108.
109.
Wolowczuk I Hennart B Leloire A Bessede A Soichot M Taront S Caiazzo R Raverdy V Pigeyre M;ABOS Consortium Guillemin GJ Allorge D Pattou F Froguel P Poulain-Godefroy O 《American journal of physiology. Regulatory, integrative and comparative physiology》2012,303(2):R135-R143
Human obesity is characterized by chronic low-grade inflammation in white adipose tissue and is often associated with hypertension. The potential induction of indoleamine 2,3-dioxygenase-1 (IDO1), the rate-limiting enzyme in tryptophan/kynurenine degradation pathway, by proinflammatory cytokines, could be associated with these disorders but has remained unexplored in obesity. Using immunohistochemistry, we detected IDO1 expression in white adipose tissue of obese patients, and we focused on its contribution in the regulation of vascular tone and on its immunoregulatory effects. Concentrations of tryptophan and kynurenine were measured in sera of 36 obese and 15 lean women. The expression of IDO1 in corresponding omental and subcutaneous adipose tissues and liver was evaluated. Proinflammatory markers and T-cell subsets were analyzed in adipose tissue via the expression of CD14, IL-18, CD68, TNFα, CD3ε, FOXP3 [a regulatory T-cell (Treg) marker] and RORC (a Th17 marker). In obese subjects, the ratio of kynurenine to tryptophan, which reflects IDO1 activation, is higher than in lean subjects. Furthermore, IDO1 expression in both adipose tissues and liver is increased and is inversely correlated with arterial blood pressure. Inflammation is associated with a T-cell infiltration in obese adipose tissue, with predominance of Th17 in the omental compartment and of Treg in the subcutaneous depot. The Th17/Treg balance is decreased in subcutaneous fat and correlates with IDO1 activation. In contrast, in the omental compartment, despite IDO1 activation, the Th17/Treg balance control is impaired. Taken together, our results suggest that IDO1 activation represents a local compensatory mechanism to limit obesity-induced inflammation and hypertension. 相似文献
110.
With complete genome sequences now available for several prokaryotic and eukaryotic organisms, biological researchers are charged with the task of assigning molecular and cellular functions to thousands of predicted gene products. To address this problem, the field of proteomics seeks to develop and apply methods for the global analysis of protein expression and protein function. Here we review a promising new class of proteomic strategies that utilizes synthetic chemistry to create tools and assays for the characterization of protein samples of high complexity. These approaches include the development of chemical affinity tags to measure the relative expression level and post-translational modification state of proteins in cell and tissue proteomes. Additionally, we discuss the emerging field of activity-based protein profiling, which aims to synthesize and apply small molecule probes that monitor dynamics in protein function in complex proteomes. 相似文献