Wernicke's area homologue in chimpanzees (Pan troglodytes) and its relation to the appearance of modern human language

Human language is distinctive compared with the communication systems of other species. Yet, several questions concerning its emergence and evolution remain unresolved. As a means of evaluating the neuroanatomical changes relevant to language that accompanied divergence from the last common ancestor of chimpanzees, bonobos and humans, we defined the cytoarchitectonic boundaries of area Tpt, a component of Wernicke''s area, in 12 common chimpanzee brains and used design-based stereologic methods to estimate regional volumes, total neuron number and neuron density. In addition, we created a probabilistic map of the location of area Tpt in a template chimpanzee brain coordinate space. Our results show that chimpanzees display significant population-level leftward asymmetry of area Tpt in terms of neuron number, with volume asymmetry approaching significance. Furthermore, asymmetry in the number of neurons in area Tpt was positively correlated with asymmetry of neuron numbers in Brodmann''s area 45, a component of Broca''s frontal language region. Our findings support the conclusion that leftward asymmetry of Wernicke''s area originated prior to the appearance of modern human language and before our divergence from the last common ancestor. Moreover, this study provides the first evidence of covariance between asymmetry of anterior and posterior cortical regions that in humans are important to language and other higher order cognitive functions.     

Development, set-up and first results for a one-channel near-infrared spectroscopy system.

Abstract Near-infrared spectroscopy (NIRS) is a non-invasive optical technique that can be used to assess functional activity in the human brain. This work describes the set-up of a one-channel NIRS system designed for use as an optical brain-computer interface (BCI) and reports on first measurements of deoxyhemoglobin (Hb) and oxyhemoglobin (HbO(2)) changes during mental arithmetic tasks. We found relatively stable and reproducible hemodynamic responses in a group of 13 healthy subjects. Unexpected observations of a decrease in HbO(2) and increase in Hb concentrations measured over the prefrontal cortex were in contrast to the typical hemodynamic responses (increase in HbO(2), decrease in Hb) during cortical activation previously reported.     

Prospective sustainability assessment: the case of wood in automotive applications

Purpose

The introduction of renewable materials into automotive applications is perceived as an innovative lightweight solution. Wood-based materials are advantageous in that they have potentially lower environmental impacts as compared with other materials such as steel. However, using wood per se does not automatically ensure more sustainability. Few prospective sustainability assessment methods or studies on the use of wood-based materials in automotive applications have been carried out, although these are needed to reduce unintended, negative sustainability effects and to support sustainable oriented research and innovation. Therefore, this study was conducted to assess the potential sustainability effects and consequences of introducing a wood-based component into an automotive application.

Methods

A combination of methods was used to analyze the potential sustainability effects when introducing wood into automotive applications. This prospective life cycle sustainability analysis solely relied on secondary data. The environmental impacts were analyzed using a simplified environmental life cycle assessment on the product level. A multi-regional input-output-based assessment was conducted to model the country-specific environmental and socioeconomic consequences. The potential shift in social risks and opportunities on a national scale was analyzed by conducting a generic social life cycle assessment. Various aspects of each approach differ, with each providing a specific perspective of the system under study.

Results and discussion

The results indicate that implementing wood into automotive application can have environmental, social, and economic benefits, according to most of the indicators analyzed. Mostly due to the product weight reduction due to the use of a wood-based component, the results show that environmental impacts decrease. Some possible consequences of using wood-based materials are increased value added and increasing the number of jobs in European countries. Similarly, the social risks and opportunities are shifted from countries all over the world to European countries, which perform better than developing countries according to several indicators. However, some indicators, such as migrant acceptance or local supplier quantity, perform better in the current situation.

Conclusions

The presented case study is particularly notable, because the results clearly indicate the advantages of using wood-based materials in automotive applications, although the application of such relatively holistic and complex approaches often may lead to rather indifferent pictures. Policy makers, researchers, and companies can apply this combination of methods that rely solely on generic data to obtain both feasible and informative results. These methods also allow users to link the product level assessment with a regional and social perspective and screen critical topics to support sustainability research and innovation.