排序方式: 共有51条查询结果,搜索用时 15 毫秒
31.
32.
V A Melikhov I A Spiridonova T A Ushakova V V Tsybanov M K Kudinova L N Ostanina E M Singan M V Baturina L P Ivanitskaia 《Antibiotiki i khimioterapii͡a》1991,36(4):5-8
An antibiotic complex was isolated from culture 8-86 referred to Bacillus. The complex consisted of components 8-86A and 8-86B active against gram-negative organisms. By its physico-chemical properties such as IR and UV spectra, amino acid composition, specific rotation and fatty acid composition component 8-86B was shown to be close to polymyxin F. 相似文献
33.
A. N. Sinyakov E. V. Kostina G. A. Maksakova O. A. Baturina V. A. Ryabinin 《Russian Journal of Bioorganic Chemistry》2007,33(5):531-533
A possibility of using oligonucleotide conjugates with minor groove ligands as probes for hybridization microarray chips was studied. The oligonucleotide conjugates contain a hairpin ligand (MGB) composed of two tripyrrolcarboxamide residues with an aminocaproic acid residue as a linker and bound to the oligonucleotide duplex AT tract in a site-specific manner. We used as (5′-3′)-probes: GACAAGAp, GACAAAAp, GACAAGA-MGB, and GACAAAA-MGB. The oligonucleotides labeled with the Cy3 cyanine dye, Cy3-ACTAATTTTGTC and Cy3-ACTAATCTTGTC, were used as targets. The maximal MGB effect on the fluorescence level of microarray chip spots, which caused its fourfold increase as compared with the initial unmodified duplex, was observed for the duplex containing only AT pairs in the ligand binding site. The presence of AC and GT mutations in the binding site (imperfect duplexes) or a CG pair (perfect duplex) affect the change in fluorescence level to a considerably lesser degree. 相似文献
34.
Kiselev I. S. Kulakova O. G. Danilova L. V. Baturina O. A. Kabilov M. R. Popova E. V. Boyko A. N. Favorova O. O. 《Molecular Biology》2022,56(3):417-423
Molecular Biology - The pathogenesis of multiple sclerosis (MS), a chronic disease of the CNS, includes autoimmune and neurodegenerative components. In most cases, patients develop... 相似文献
35.
The total protein fraction was obtained by extraction with nonionic detergent NP-40. The fraction composition and molecular parameters were studied with DDS-Na electrophoresis in polyacryl amide gel. Common properties of the Corynebacterium diphtheriae protein fraction 66 kD and an analogous fraction of the cell walls of staphylococci and the measles virus were shown with immunoblotting. Cell-mediated mechanisms of the immune response to contact with antigens of Corynebacterium diphtheriae cell walls were revealed. 相似文献
36.
37.
38.
G. S. Baturina L. E. Katkova E. I. Solenov L. N. Ivanova 《Doklady biological sciences》2017,473(1):43-45
In the course of adaptation of the rat kidney collecting duct cells to hypo-osmotic medium, the organic anion transporter inhibitor probenecid reduced significantly the regulatory cell volume decrease in response to a hypotonic shock. Both probenecid and hypotonic shock delayed significantly the entry into a cell of the fluorescent dye calcein, which exists as anion at neutral pH. Thus, the organic osmolyte transport plays an important role in the regulatory decrease of the principal cell volume under the hypo-osmotic conditions. 相似文献
39.
Solenov EI Baturina GS Ivanova LN 《Rossi?skii fiziologicheski? zhurnal imeni I.M. Sechenova / Rossi?skaia akademiia nauk》2001,87(7):965-972
Desmopressin caused a statistically significant increase in the water permeability of the outer medullary collecting ducts (OMCD) in 22-days old rats. Concentration of specific V2 receptors increased during postnatal period. Comparison of the V2 receptors concentration, mRNA contents, and changes of water permeability in response to desmopressin suggests that parts of transduction mechanism is situated deeper than the receptors, determines the physiological mechanism at the end of weaning period. 相似文献
40.
The mechanism of the intranasal action of dermorphin in representatives of 2 classes of vertebrates]
L S Chernova A A Kamenski? G A Maliukina E Iu Baturina V I De?gin E P Iarova 《Zhurnal evoliutsionno? biokhimii i fiziologii》1992,28(1):45-48
It has been shown that endogenous opioid dermorphin induces effective analgesia after intranasal injection to fish (0.02-0.20 mg/kg) and rats (0.005 mg/kg). Maintenance of dermorphin analgesia after olfactory and trigeminal denervation indicates that the analgetic effect is not realized via the olfactory receptors or free terminals of the trigeminal nerve. 相似文献