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591.
Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF
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Cluster Computing - The Low Power and Lossy Networks (LLNs) in the Internet of Things environment comprising constrained embedded devices have particular routing requirements that are well... 相似文献
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How many antibiotics are produced by the genus Streptomyces? 总被引:7,自引:0,他引:7
Milind G. Watve Rashmi Tickoo Maithili M. Jog Bhalachandra D. Bhole 《Archives of microbiology》2001,176(5):386-390
Streptomyces is the largest antibiotic-producing genus in the microbial world discovered so far. The number of antimicrobial compounds reported from the species of this genus per year increased almost exponentially for about two decades, followed by a steady rise to reach a peak in the 1970s, and with a substantial decline in the late 1980s and 1990s. The cumulative number shows a sigmoid curve that is much flatter than what a logistic equation would predict. We attempted to fit a mathematical model to this curve in order to estimate the number of undiscovered antimicrobials from this genus as well as to predict the trends in the near future. A model assuming that the screening efforts are encouraged by a previous year's success and that the probability of finding a new antibiotic is a function of the fraction of antibiotics undiscovered so far offered a good fit after optimizing parameters. The model estimated the total number of antimicrobial compounds that this genus is capable of producing to be of the order of a 100,000 - a tiny fraction of which has been unearthed so far. The decline in the slope appeared to be due to a decline in screening efforts rather than an exhaustion of compounds. Left to itself, the slope will become zero in the next one or two decades, but if the screening efforts are maintained constant, the rate of discovery of new compounds will not decline for several decades to come. 相似文献
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Total population of cellulose degrading bacteria was studied in a landfill ecosystem as a part of microbial diversity study.
Samples were obtained from 3 and 5 feet depth of a local landfill being operated for past 10 years. Among many isolates, 22
bacterial strains were selected based on their capability to decompose carboxymethyl cellulose (CMC). These isolates were
cultivated on agar medium with CMC as the carbon source. All isolates were Gram positive, endospore forming and alkalophilic
bacteria with optimum growth pH 9–10. They were grouped based on the phenotypic and chemotaxonomic characters and representative
strains of different groups along with high carboxymethyl cellulase (CMCase) producing strains were included for further characterization.
Analysis of 16S rRNA gene indicated that these strains belong to different species of the genus Bacillus. Maximum CMCase activity of 4.8 U/ml at 50°C was obtained by strain LFC15. Results in the present study indicated the potential
of waste land ecosystems such as landfill are potential source for isolation of industrially important microorganisms. 相似文献
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Li-Bing Yuan Mo-Xian Chen Lin-Na Wang Rashmi Sasidharan Laurentius A. C. J. Voesenek Shi Xiao 《Plant biotechnology journal》2023,21(3):466-481
Submergence limits plants' access to oxygen and light, causing massive changes in metabolism; after submergence, plants experience additional stresses, including reoxygenation, dehydration, photoinhibition and accelerated senescence. Plant responses to waterlogging and partial or complete submergence have been well studied, but our understanding of plant responses during post-submergence recovery remains limited. During post-submergence recovery, whether a plant can repair the damage caused by submergence and reoxygenation and re-activate key processes to continue to grow, determines whether the plant survives. Here, we summarize the challenges plants face when recovering from submergence, primarily focusing on studies of Arabidopsis thaliana and rice (Oryza sativa). We also highlight recent progress in elucidating the interplay among various regulatory pathways, compare post-hypoxia reoxygenation between plants and animals and provide new perspectives for future studies. 相似文献
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Helicoverpa armigera (Hübner) is one of the most prominent polyphagous species of the Heliothinae pest complex that inflicts severe damage to a wide range of crops in India. Knowledge regarding the population structure of the pest species, whether morphological or genetic, is considered as an essential tool in making effective management decisions. Thus here, we performed the phenotypic characterization of H. armigera populations collected from varied geographic locations across India. Studied populations differed significantly for several external morphometric traits studied at larval, pupal and adult stages. Significant differences were also observed with respect to the intensity of black pigmentation on larval body as well as adult eye and forewing colour patterns. Besides external phenotypic traits, the length of genital organs like aedeagus and valva in males, and bursa copulatrix and bursa seminalis in females also differed significantly amongst populations. The dendrogram based on selected traits showed clear cut differentiation of studied populations into two major groups, one including all the South Zone populations and the other having populations from North and Central Zones. Differences based on phenotyping in the present study indicate the possibility of the existence of different subspecies within the Indian populations of H. armigera. 相似文献
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