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161.
Fatemeh Hemmati Rasoul Ghasemi Norlinah Mohamed Ibrahim Leila Dargahi Zahurin Mohamed Azman Ali Raymond Abolhassan Ahmadiani 《Molecular neurobiology》2014,50(3):797-810
Neuroinflammation is known as a key player in a variety of neurodegenerative and/or neurological diseases. Brain Toll-like receptors (TLRs) are leading elements in the initiation and progression of neuroinflammation and the development of different neuronal diseases. Furthermore, TLR activation is one of the most important elements in the induction of insulin resistance in different organs such as the central nervous system. Involvement of insulin signaling dysregulation and insulin resistance are also shown to contribute to the pathology of neurological diseases. Considering the important roles of TLRs in neuroinflammation and central insulin resistance and the effects of these processes in the initiation and progression of neurodegenerative and neurological diseases, here we are going to review current knowledge about the potential crosstalk between TLRs and insulin signaling pathways in neuroinflammatory disorders of the central nervous system. 相似文献
162.
鄂西北丹江口库区大气氮沉降 总被引:8,自引:4,他引:8
利用雨量器在鄂西北丹江口库区连续3a采集降雨样品,研究了大气氮沉降的变化动态。结果表明:2009—2011年月均总氮(TN)浓度为3.70—10.36 mg/L,与当月降雨量呈极显著线性负相关(R=-0.592**,n=32),季均TN浓度为冬季(8.21 mg/L)春季(3.94 mg/L)秋季(3.23 mg/L)夏季(2.70 mg/L),年均TN浓度为3.70 mg/L。大气氮素年均干湿总沉降量为26.53 kg/hm2,其中干沉降为7.80 kg/hm2,占总沉降量的29.4%;湿沉降为18.73 kg/hm2,占总沉降量的70.6%。干沉降中铵态氮(NH+4-N)、硝态氮(NO-3-N)、可溶性有机氮(DON)和颗粒态氮(PN)分别占TN的22.1%、16.8%、37.2%和23.9%,湿沉降中它们分别为TN的36.6%、34.4%、12.9%和16.1%。 相似文献
163.
羊草草地生长季放牧山羊采食量和食性选择 总被引:12,自引:1,他引:12
在松嫩平原羊草草地,通过控制放牧实验对山羊的时限采食量和食性选择进行了研究。结果表明:(1)5-9月份,山羊的时限(1h)采食量平均为0.42kg干物质,其季节动态为5月份最低,随季节推移不断增大,8月份达到最大,9月份又有所减小;时限采食量基本上随放牧率减小而增大,但在最低放牧率小区有所减小。(2)山羊的食性选择随季节推移和放牧率不同而变化。(3)山羊对20-25cm高度草层的选择性最高;各高度草层的食性选择指数随季节推移和放牧率不同而变化;山羊对不同植物的高度选择性存在差异,但高度选择指数的最大值都在15-30cm范围内。 相似文献
164.
为揭示我国西藏高原湖泊原生动物群落结构特征及垂直分布格局,于2017年11月及2018年5月和9月,在巴松措中心分7层设置采样点,利用25号浮游生物网采集原生动物。采用活体观察和固定染色相结合的方法,共鉴定到原生动物195种(其中春季86种,夏季93种,秋季80种),隶属于2门11纲24目43科59属。其中以肉鞭门种类较丰富,砂壳类纤毛虫占优势。垂直分布的物种组成和群落结构复杂表现为:表层>中层>底层,物种多样性、丰富度和优势度指数表现为:表层>中层>底层,均匀度指数大多数为1;季节分布的物种组成和群落结构群复杂程度表现为:夏季>春季>秋季,物种多样性、丰富度指数表现为:夏季>秋季>春季,优势度指数表现为:夏季>秋季>春季,均匀度指数表现为:秋季>春季>夏季;优势物种和群落结构都会随水深的增加而减少。总体呈现出物种多样性较低、均匀度较高,具有明显的时空异质性。 相似文献
165.
Two populations of Anadara senilis were sampled periodicallyin a lagoon of Senegal. Spatfall occurs in summer during therainy season. Population density decreases from about 50, 000.m2,two months after spatfall, down to 6, 750 one year later and750 after 28 months. The average growth, measured on the surfaceof the shell, following the umbo rim axis is 0.8 mm per month.The main reduction in growth rate occurs in winter and endsby the deposition of a growth ring. A second growth reductiontakes place during the rainy season and sometimes ends by aweak growth ring. The microgrowth increments are conspicuousand widest during spring equinox. They are not directly relatedto the tidal cycle, but it was impossible to determine if theyhave a tidal or a daily periodicity. (Received 11 February 1990; accepted 16 July 1993) 相似文献
166.
Rosario Francisco‐Velilla Embarc‐Buh Azman Encarnacion Martinez‐Salas 《BioEssays : news and reviews in molecular, cellular and developmental biology》2019,41(4)
The fate of cellular RNAs is largely dependent on their structural conformation, which determines the assembly of ribonucleoprotein (RNP) complexes. Consequently, RNA‐binding proteins (RBPs) play a pivotal role in the lifespan of RNAs. The advent of highly sensitive in cellulo approaches for studying RNPs reveals the presence of unprecedented RNA‐binding domains (RBDs). Likewise, the diversity of the RNA targets associated with a given RBP increases the code of RNA–protein interactions. Increasing evidence highlights the biological relevance of RNA conformation for recognition by specific RBPs and how this mutual interaction affects translation control. In particular, noncanonical RBDs present in proteins such as Gemin5, Roquin‐1, Staufen, and eIF3 eventually determine translation of selective targets. Collectively, recent studies on RBPs interacting with RNA in a structure‐dependent manner unveil new pathways for gene expression regulation, reinforcing the pivotal role of RNP complexes in genome decoding. 相似文献
167.
R. PANADERO G. VARAS G. PAJARES F. MARKINA C. LÓPEZ P. DÍAZ A. PÉREZ‐CREO A. PRIETO P. DÍEZ‐BAÑOS P. MORRONDO 《Medical and veterinary entomology》2017,31(1):94-96
Subcutaneous larvae of Hypoderma spp. (Diptera: Oestridae) were detected in the dorsal region in 10 roe deer, Capreolus capreolus (Artiodactyla: Cervidae), hunted in central Spain between January and March 2016. All larvae were found in the inner side of the hide during the skinning of the animals. The study of the morphological features of eight larvae of different stages collected from two animals allowed the identification of Hypoderma actaeon Brauer. The small size (4–5 mm) of some of the first instars suggests that the internal lifecycle of H. actaeon may be exclusively subcutaneous. This is the first confirmation of H. actaeon in roe deer; however, further studies to assess the spread of the parasite and to follow the evolution of this myiasis in roe deer are needed. 相似文献
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