Flavonoids from Echinacea purpurea

Two compounds, nicotiflorin and rutin, are isolated and idenitified from flowers of Echinacea purpurea (L.) Moench., of the family Asteraceae, cultivated in Samara oblast. It is established that nicotiflorin (3-O-rutinoside campherol) is the dominant flavonoid of Echinacea purpurea; it is described along with rutin for the first time for this plant, cultivated in the Russian Federation and CIS countries.     

Interferon type I in protective body reactions in an experimental Klebsiella infection]

The study on mice with experimental generalized Klebsiella infection, carried out with the use of microbiologic, immunologic and pathomorphologic methods, revealed that the intraperitoneal injection of type I interferon into the animals prevented their death and led to the rapid elimination of the infective agent from their body, enhanced the phagocytic and metabolic activity of polymorphonuclear lymphocytes of their peritoneal exudate, decreased the manifestation of microcirculatory and dystrophic changes in the parenchyma of their internal organs.