全文获取类型
收费全文 | 139篇 |
免费 | 8篇 |
出版年
2023年 | 1篇 |
2022年 | 2篇 |
2021年 | 3篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 1篇 |
2017年 | 5篇 |
2016年 | 2篇 |
2015年 | 4篇 |
2014年 | 7篇 |
2013年 | 2篇 |
2012年 | 7篇 |
2011年 | 6篇 |
2010年 | 3篇 |
2009年 | 9篇 |
2008年 | 13篇 |
2007年 | 5篇 |
2006年 | 3篇 |
2005年 | 3篇 |
2004年 | 5篇 |
2003年 | 4篇 |
2002年 | 1篇 |
2001年 | 3篇 |
1992年 | 1篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1986年 | 2篇 |
1985年 | 3篇 |
1984年 | 9篇 |
1983年 | 4篇 |
1982年 | 5篇 |
1981年 | 1篇 |
1979年 | 3篇 |
1975年 | 1篇 |
1974年 | 3篇 |
1973年 | 2篇 |
1972年 | 5篇 |
1970年 | 1篇 |
1967年 | 1篇 |
1966年 | 1篇 |
1959年 | 2篇 |
1958年 | 1篇 |
排序方式: 共有147条查询结果,搜索用时 31 毫秒
61.
Microbial biomass production on solid hydrocarbons 总被引:1,自引:0,他引:1
P. M. Amin J. N. Nigam B. K. Lonsane B. Baruah H. D. Singh J. N. Baruah M. S. Iyengar 《Folia microbiologica》1973,18(1):49-55
Solid hydrocarbon utilizing bacterial isolates were screened and the strains were examined for biomass production, growth on different solid hydrocarbons, protein contents, and amino acid composition. Conversion rate of solid hydrocarbon to biomass was 40–100 per cent depending on the substrate used. Linear growth curves were obtained in all cases. 相似文献
62.
The aerial parts of Calea clematidea gave three new germacranolides, those of Viguiera procumbens two orizabin derivatives and those of V. linearis dihydrobudlein A. In addition to these lactones, several known ones were isolated. 相似文献
63.
64.
Vishnu S. Shukla Subhash C. Dutta Robindra N. Baruah Ram P. Sharma Gopalakrishna Thyagarajan Werner Herz Narendra Kumar Kinzo Watanabe John F. Blount 《Phytochemistry》1982,21(7):1725-1731
The isolation of three new terpenoid 5-methylcoumarins in the form of diastereomeric mixtures from a north Indian collection of Ethulia conyzoides is reported. Stereochemistries were deduced by X-ray analysis of a pure acetate isomer obtained on acetylation of one of the diastereomeric mixtures. 相似文献
65.
66.
Emma V. Dixon Jolyon K. Claridge David J. Harvey Kavitha Baruah Xiaojie Yu Snezana Vesiljevic Susan Mattick Laura K. Pritchard Benjamin Krishna Christopher N. Scanlan Jason R. Schnell Matthew K. Higgins Nicole Zitzmann Max Crispin 《The Journal of biological chemistry》2014,289(20):13876-13889
Endoglycosidase S (EndoS) is a glycoside-hydrolase secreted by the bacterium Streptococcus pyogenes. EndoS preferentially hydrolyzes the N-linked glycans from the Fc region of IgG during infection. This hydrolysis impedes Fc functionality and contributes to the immune evasion strategy of S. pyogenes. Here, we investigate the mechanism of human serum IgG deactivation by EndoS. We expressed fragments of IgG1 and demonstrated that EndoS was catalytically active against all of them including the isolated CH2 domain of the Fc domain. Similarly, we sought to investigate which domains within EndoS could contribute to activity. Bioinformatics analysis of the domain organization of EndoS confirmed the previous predictions of a chitinase domain and leucine-rich repeat but also revealed a putative carbohydrate binding module (CBM) followed by a C-terminal region. Using expressed fragments of EndoS, circular dichroism of the isolated CBM, and a CBM-C-terminal region fusion revealed folded domains dominated by β sheet and α helical structure, respectively. Nuclear magnetic resonance analysis of the CBM with monosaccharides was suggestive of carbohydrate binding functionality. Functional analysis of truncations of EndoS revealed that, whereas the C-terminal of EndoS is dispensable for activity, its deletion impedes the hydrolysis of IgG glycans. 相似文献
67.
68.
The complexes [Cu2(o-NO2-C6H4COO)4(PNO)2] (1), [Cu2(C6H5COO)4(2,2′-BPNO)]n (2), [Cu2(C6H5COO)4(4,4′-BPNO)]n (3), [Cu(p-OH-C6H4COO)2(4,4′-BPNO)2·H2O]n (4), (where PNO = pyridine N-oxide, 2,2′-BPNO = 2,2′-bipyridyl-N,N′-dioxide, 4,4′-BPNO = 4,4′-bipyridyl-N,N′-dioxide) are prepared and characterized and their magnetic properties are studied as a function of temperature. Complex 1 is a discrete dinuclear complex while complexes 2-4 are polymeric of which 2 and 3 have paddle wheel repeating units. Magnetic susceptibility measurements from polycrystalline samples of 1-4 revealed strong antiferromagnetic interactions within the {Cu2}4+ paddle wheel units and no discernible interactions between the units. The complex 5, [Cu(NicoNO)2·2H2O]n·4nH2O, in which the bridging ligand to the adjacent copper(II) ions is nicotinate N-oxide (NicoNO) the transmitted interaction is very weakly antiferromagnetic. 相似文献
69.
T. Das A. K. Pal † S. K. Chakraborty ‡ S. M. Manush R. S. Dalvi S. K. Apte § N. P. Sahu K. Baruah || 《Journal of fish biology》2009,74(7):1487-1498
The biochemical and stress responses of two Indian major carps, rohu Labeo rohita and mrigal Cirrhinus mrigala were studied after acclimating them to four preset temperatures (26, 31, 33 and 36° C) for 30 days. The blood glucose and liver glycogen levels showed an inverse trend in both the species and were significantly different in L. rohita at higher temperatures. The decrease in the liver glycogen level of C. mrigala , however, was not significant. Plasma cortisol levels increased significantly whereas the ascorbic acid content in the brain and kidney of both the species decreased significantly with increasing temperatures. Total lipid content in the liver of both the species decreased significantly with increasing acclimation temperatures. The phospholipid concentration decreased in L. rohita with increasing acclimation temperatures, and in C. mrigala the values decreased up to 33° C and increased at 36° C. In C. mrigala , the cholesterol level decreased up to 33° C and then increased at 36° C, but the absolute value was lower in comparison to L. rohita . The cholesterol levels, however, were not significantly different in L. rohita . Triglycerides and free fatty acids concentrations decreased significantly with increasing acclimation temperatures in both the species. The present study indicates species-specific metabolic responses of L. rohita and C. mrigala to thermal acclimation. 相似文献
70.
Kartik Baruah Parisa Norouzitallab Li Shihao Patrick Sorgeloos Peter Bossier 《Fish & shellfish immunology》2013,34(1):183-191
The 70 kDa heat shock proteins (Hsp70s) are highly conserved in evolution, leading to striking similarities in structure and composition between eukaryotic Hsp70s and their homologs in prokaryotes. The eukaryotic Hsp70 like the DnaK (Escherichia coli equivalent Hsp70) protein, consist of three functionally distinct domains: an N-terminal 44-kDa ATPase portion, an 18-kDa peptide-binding domain and a C-terminal 10-kDa fragment. Previously, the amino acid sequence of eukaryotic (the brine shrimp Artemia franciscana) Hsp70 and DnaK proteins were shown to share a high degree of homology, particularly in the peptide-binding domain (59.6%, the putative innate immunity-activating portion) compared to the N-terminal ATPase (48.8%) and the C-terminal lid domains (19.4%). Next to this remarkable conservation, these proteins have been shown to generate protective immunity in Artemia against pathogenic Vibrio campbellii. This study, aimed to unravel the Vibrio-protective domain of Hsp70s in vivo, demonstrated that gnotobiotically cultured Artemia fed with recombinant C-terminal fragment (containing the conserved peptide binding domain) of Artemia Hsp70 or DnaK protein were well protected against subsequent Vibrio challenge. In addition, the prophenoloxidase (proPO) system, at both mRNA and protein activity levels, was also markedly induced by these truncated proteins, suggesting epitope(s) responsible for priming the proPO system and presumably other immune-related genes, consequently boosting Artemia survival upon challenge with V. campbellii, might be located within this conserved region of the peptide binding domain. 相似文献