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131.
This paper examines the roots of attitudes toward immigration among Australians of English-speaking background using the 1998, 2001, 2004, and 2007 Australian Election Studies. The paper demonstrates that attitudes toward immigration in Australia have their roots in multiple sources, some of them relating to the local context in which individuals reside, others in the socio-economic and financial situation experienced by individuals. Attitudes toward immigration in Australia are also related to attitudinal factors and historical legacies that manifest themselves in mistrust and suspicion toward Asian neighbours. Finally, the paper demonstrates that the presence of immigrants and ethnic minorities influences Australians' attitudes toward immigration but that this effect must be understood in conjunction with the educational context of the areas of residence. While in high education areas Australians tend to react positively to the presence of immigrants, in low education areas they tend to react negatively to the presence of immigrants. 相似文献
132.
Antoine G. Almonte Laura H. Qadri Faraz A. Sultan Jennifer A. Watson Daniel J. Mount Gavin Rumbaugh J. David Sweatt 《Journal of neurochemistry》2013,124(1):109-122
Protease‐activated receptor‐1 (PAR1) is an unusual G‐protein coupled receptor (GPCR) that is activated through proteolytic cleavage by extracellular serine proteases. Although previous work has shown that inhibiting PAR1 activation is neuroprotective in models of ischemia, traumatic injury, and neurotoxicity, surprisingly little is known about PAR1's contribution to normal brain function. Here, we used PAR1?/? mice to investigate the contribution of PAR1 function to memory formation and synaptic function. We demonstrate that PAR1?/? mice have deficits in hippocampus‐dependent memory. We also show that while PAR1?/? mice have normal baseline synaptic transmission at Schaffer collateral‐CA1 synapses, they exhibit severe deficits in N‐methyl‐d ‐aspartate receptor (NMDAR)‐dependent long‐term potentiation (LTP). Mounting evidence indicates that activation of PAR1 leads to potentiation of NMDAR‐mediated responses in CA1 pyramidal cells. Taken together, this evidence and our data suggest an important role for PAR1 function in NMDAR‐dependent processes subserving memory formation and synaptic plasticity. 相似文献
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136.
Astrid Goubet Antoine Chardon Pawan Kumar Pawan K. Sharma Rakesh N. Veedu 《Bioorganic & medicinal chemistry letters》2013,23(3):761-763
C5-Ethynylbenzenesulfonamide-modified nucleotide (EBNA) was investigated as substrate of various DNA polymerases. The experiments revealed that KOD, Phusion and Klenow DNA polymerases successfully accepted EBNA-T nucleotide as a substrate and yielded the fully extended DNA. KOD DNA polymerase was found to be the most efficient enzyme to furnish EBNA-T containing DNA in good yields. Phusion DNA polymerase efficiently amplified the template containing EBNA-T nucleotides by PCR. 相似文献
137.
Özge Balkız Ortaç Onmuş Mehmet Sıkı Ömer Döndürenc Orhan Gül Antoine Arnaud 《Zoology in the Middle East.》2013,59(3):201-214
The Greater Flamingo Phoenicopterus roseus is a waterbird commonly found in saline and brackish lagoons throughout the Mediterranean Region. We have gathered existing data on Greater Flamingos in Turkey and carried out field surveys to present the most up to date information on wintering (1999–2014) and breeding (1969– 2014). The wintering population of flamingos shows an increasing trend with 54,947±20,794 individuals mainly concentrated in the Gediz, Büyük Menderes and Çukurova deltas, respectively. Breeding attempts were recorded in at least seven wetlands in Turkey in the past, yet after 1999 most of the colonies were abandoned due to basin scale intensive water management practices in Central Anatolia. Currently, only Tuz Lake and Gediz Delta are used as regular breeding sites, while breeding has been recorded sporadically in Ac?göl and Ak?ehir Lakes. The breeding colony of Tuz Lake is of prime importance at the Mediterranean scale, with the number of young chicks in 2011, 2012 and 2013 accounting for the highest number of fledglings in the Mediterranean Region and West Africa (18,418, 20,274 and 20,292 respectively). Finally, building upon the previous findings about Turkey and the western Mediterranean metapopulation links, recent resightings of Turkish flamingos (despite the limited numbers) confirm post-fledging and natal dispersal reaching the western Mediterranean Basin and West Africa. Flamingos from Turkey were also found to disperse to Israel and to a region outside the known flyways of the western Mediterranean and West African flamingos (i.e. to Israel and UAE). Thus, Turkey, due to its geographic position, appears to be a crossroad between the western and eastern Mediterranean Region and southwest Asia. 相似文献
138.
Christin Liptow Anne-Marie Tillman Matty Janssen Ola Wallberg Glenn A. Taylor 《The International Journal of Life Cycle Assessment》2013,18(5):1071-1081
Purpose
In order to reduce its environmental impact, the chemical industry no longer produces base chemicals such as ethylene, solely from fossil, but also from biomass-based feedstocks. However, a biomass option suitable for one region might not be as suitable for another region due to, e.g., long transport and the related environmental. Therefore, local biomass alternatives and the environmental impact related to the production of chemicals from these alternatives need to be investigated. This study assesses the environmental impact of producing ethylene from Swedish wood ethanol.Methods
The study was conducted following the methodology of life cycle assessment. The life cycle was assessed using a cradle-to-gate perspective for the production of 50,000 tonnes ethylene/year for the impact categories global warming, acidification (ACP), photochemical ozone creation, and eutrophication (EP).Results and discussion
The production of enzymes used during the life cycle had a significant effect on all investigated impacts. However, reduced consumption of enzyme product, which could possibly be realized considering the rapid development of enzymes, lowered the overall environmental impact of the ethylene. Another approach could be to use alternative hydrolyzing agents. However, little information on their environmental impact is available. An additional key contributor, with regard to ACP, EP, and POCP, was the ethanol production. Therefore, further improvements with regard to the process’ design may have beneficial effects on its environmental impact.Conclusions
The study assessed the environmental impact of wood ethylene and pointed to several directions for improvements, such as improved enzyme production and reduced consumption of enzyme products. Moreover, the analysis showed that further investigations into other process options and increase of ethylene production from biomass are worth continued research. 相似文献139.
Oylum Erkus Victor CL de Jager Maciej Spus Ingrid J van Alen-Boerrigter Irma MH van Rijswijck Lucie Hazelwood Patrick WM Janssen Sacha AFT van Hijum Michiel Kleerebezem Eddy J Smid 《The ISME journal》2013,7(11):2126-2136
Maintenance of a high degree of biodiversity in homogeneous environments is poorly understood. A complex cheese starter culture with a long history of use was characterized as a model system to study simple microbial communities. Eight distinct genetic lineages were identified, encompassing two species: Lactococcus lactis and Leuconostoc mesenteroides. The genetic lineages were found to be collections of strains with variable plasmid content and phage sensitivities. Kill-the-winner hypothesis explaining the suppression of the fittest strains by density-dependent phage predation was operational at the strain level. This prevents the eradication of entire genetic lineages from the community during propagation regimes (back-slopping), stabilizing the genetic heterogeneity in the starter culture against environmental uncertainty. 相似文献
140.
We propose a novel deception detection system based on Rapid Serial Visual Presentation (RSVP). One motivation for the new method is to present stimuli on the fringe of awareness, such that it is more difficult for deceivers to confound the deception test using countermeasures. The proposed system is able to detect identity deception (by using the first names of participants) with a 100% hit rate (at an alpha level of 0.05). To achieve this, we extended the classic Event-Related Potential (ERP) techniques (such as peak-to-peak) by applying Randomisation, a form of Monte Carlo resampling, which we used to detect deception at an individual level. In order to make the deployment of the system simple and rapid, we utilised data from three electrodes only: Fz, Cz and Pz. We then combined data from the three electrodes using Fisher''s method so that each participant was assigned a single p-value, which represents the combined probability that a specific participant was being deceptive. We also present subliminal salience search as a general method to determine what participants find salient by detecting breakthrough into conscious awareness using EEG. 相似文献