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排序方式: 共有310条查询结果,搜索用时 62 毫秒
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The gonads of human true hermaphrodites 总被引:1,自引:0,他引:1
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Nigel K. Spurr Simon Cox Stephen P. Bryant John Attwood Elizabeth B. Robson Denis C. Shields Todd Steinbrueck Trefor Jenkins Jeffrey C. Murray Kenneth K. Kidd Marshall L. Summar Petros Tsipouras Andries E. Retief Torben A. Kruse Allen E. Bale Gilles Vergnaud James L. Weber O.W. McBride Helen Donis-Keller Raymond L. White 《Genomics》1992,14(4):1055-1063
This paper describes the Centre d'Etude du Polymorphisme Humain (CEPH) consortium linkage map of chromosome 2. The map contains 36 loci defined by genotyping generated from the CEPH family DNAs. A total of 73 different markers were typed by 14 contributing laboratories; of these, 36 loci are ordered on the map with likelihood support of at least 1000:1. Markers are placed along the length of the chromosome but no markers were available to anchor the map at either telomere or the centromere. Multilocus linkage analysis has produced male, female, and sex-averaged maps extending for 261, 430, and 328 cM, respectively. The sex-averaged map contains five intervals greater than 15 cM and the mean genetic distance between the 36 uniquely placed loci is 9.1 cM. 相似文献
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Alex Wu Jason Brider Florian A. Busch Min Chen Karine Chenu Victoria C. Clarke Brian Collins Maria Ermakova John R. Evans Graham D. Farquhar Britta Forster Robert T. Furbank Michael Groszmann Miguel A. Hernandez-Prieto Benedict M. Long Greg Mclean Andries Potgieter G. Dean Price Robert E. Sharwood Michael Stower Erik van Oosterom Susanne von Caemmerer Spencer M. Whitney Graeme L. Hammer 《Plant, cell & environment》2023,46(1):23-44
Photosynthetic manipulation provides new opportunities for enhancing crop yield. However, understanding and quantifying the importance of individual and multiple manipulations on the seasonal biomass growth and yield performance of target crops across variable production environments is limited. Using a state-of-the-art cross-scale model in the APSIM platform we predicted the impact of altering photosynthesis on the enzyme-limited (Ac) and electron transport-limited (Aj) rates, seasonal dynamics in canopy photosynthesis, biomass growth, and yield formation via large multiyear-by-location crop growth simulations. A broad list of promising strategies to improve photosynthesis for C3 wheat and C4 sorghum were simulated. In the top decile of seasonal outcomes, yield gains were predicted to be modest, ranging between 0% and 8%, depending on the manipulation and crop type. We report how photosynthetic enhancement can affect the timing and severity of water and nitrogen stress on the growing crop, resulting in nonintuitive seasonal crop dynamics and yield outcomes. We predicted that strategies enhancing Ac alone generate more consistent but smaller yield gains across all water and nitrogen environments, Aj enhancement alone generates larger gains but is undesirable in more marginal environments. Large increases in both Ac and Aj generate the highest gains across all environments. Yield outcomes of the tested manipulation strategies were predicted and compared for realistic Australian wheat and sorghum production. This study uniquely unpacks complex cross-scale interactions between photosynthesis and seasonal crop dynamics and improves understanding and quantification of the potential impact of photosynthesis traits (or lack of it) for crop improvement research. 相似文献
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Robert M. W. Hofstra Rein P. Stulp Tineke Stelwagen Charles H. C. M. Buys Ngan Ching Cheng Huib Caron Andries Westerveld Rogier Versteeg Claus Hansen Niels Tommerup Niels Clausen 《Human genetics》1996,97(3):362-364
Neuroblastoma occasionally occurs in diseases associated with abnormal neurocrest differentiation, e.g. Hirschsprung disease. Expression studies in developing mice suggest that the proto-oncogeneRET plays a role in neurocrest differentiation. In humans expression ofRET is limited to certain tumor types, including neuroblastoma, that derive from migrating neural crest cells. Mutations ofRET are found associated with Hirschsprung disease. These data prompted us to investigate expression ofRET and to search for gene mutations in neuroblastoma. Out of 16 neuroblastoma cell lines analyzed, 9 show clear expression ofRET in a Northern blot analysis. In a single-strand conformation polymorphism (SSCP) analysis of all exons, no mutations were detected other than neutral polymorphisms. In a patient with neuroblastoma, from a family in which different neurocrestopathies, including neuroblastoma and Hirschsprung disease, had occurred, we also failed to detect RET mutations. Possibly, expression ofRET in neuroblastoma merely reflects the differentiation status of the tumor cells. The absence of mutations suggests thatRET does not play a crucial role in the tumorigenesis of neuroblastoma. 相似文献