全文获取类型
收费全文 | 8069篇 |
免费 | 626篇 |
国内免费 | 414篇 |
出版年
2024年 | 16篇 |
2023年 | 101篇 |
2022年 | 225篇 |
2021年 | 447篇 |
2020年 | 297篇 |
2019年 | 385篇 |
2018年 | 400篇 |
2017年 | 273篇 |
2016年 | 429篇 |
2015年 | 572篇 |
2014年 | 699篇 |
2013年 | 652篇 |
2012年 | 768篇 |
2011年 | 700篇 |
2010年 | 394篇 |
2009年 | 355篇 |
2008年 | 371篇 |
2007年 | 329篇 |
2006年 | 254篇 |
2005年 | 232篇 |
2004年 | 203篇 |
2003年 | 172篇 |
2002年 | 172篇 |
2001年 | 101篇 |
2000年 | 68篇 |
1999年 | 70篇 |
1998年 | 60篇 |
1997年 | 42篇 |
1996年 | 40篇 |
1995年 | 35篇 |
1994年 | 29篇 |
1993年 | 23篇 |
1992年 | 21篇 |
1991年 | 27篇 |
1990年 | 23篇 |
1989年 | 20篇 |
1988年 | 9篇 |
1987年 | 9篇 |
1986年 | 14篇 |
1985年 | 16篇 |
1983年 | 9篇 |
1982年 | 6篇 |
1981年 | 10篇 |
1980年 | 3篇 |
1979年 | 5篇 |
1978年 | 3篇 |
1972年 | 5篇 |
1971年 | 3篇 |
1969年 | 3篇 |
1959年 | 2篇 |
排序方式: 共有9109条查询结果,搜索用时 31 毫秒
91.
Wang Fubiao Sun Huimin Rong Lingling Li Zhaowei An Ting Hu Wenhai Ye Zipiao 《Plant Growth Regulation》2021,95(1):121-136
Plant Growth Regulation - To clarify the genotypic-dependent alternation in D1 protein turnover and PSII repair cycle and its relation to light intensity in senescent leaves of rice, two rice... 相似文献
92.
Kim Jung-Il Karagozlu Mustafa Zafer An Hyung-Eun Choi Tae-June Yeo Yonggu Kim Chang-Bae 《Molecular biology reports》2021,48(7):5787-5793
Molecular Biology Reports - Trichoglossus haematodus is the most popular parrots globally and one of the most bred species in Korea's zoos. However, despite its popularity, there are limited... 相似文献
93.
Zhang Keji Gao Yuan Deng Yuxiao Zhou Xiao Zhu Changqing He Zhengyu Lv Dan 《Molecular and cellular biochemistry》2021,476(1):93-107
Molecular and Cellular Biochemistry - Mesenchymal stem cells (MSCs) can alleviate acute respiratory distress syndrome (ARDS), but the mechanisms involved are unclear, especially about their... 相似文献
94.
Chen Qiumin Yu Guangchao Wang Xiangyu Meng Xiangnan Lv Chunmao 《Journal of Plant Growth Regulation》2021,40(1):147-153
Journal of Plant Growth Regulation - Powdery mildew (PM) is one of the most severe foliar diseases in cucumbers (Cucumis sativus L.), but the inheritance of PM resistance remains unclear. The... 相似文献
95.
Ji Ruiqin Gao Shiqi Bi Qing Wang Yilian Lv Mingcan Ge Wenjie Feng Hui 《Journal of Plant Growth Regulation》2021,40(1):405-422
Journal of Plant Growth Regulation - Clubroot disease, caused by Plasmodiophora brassicae Woronin infection, leads to significant yield and economic losses in cruciferous vegetables. However, the... 相似文献
96.
Wang Guang-Long An Ya-Hong Wang Ya-Hui Liu Jie-Xia Wang Ji-Zhong Sun Min Xiong Ai-Sheng 《Journal of Plant Growth Regulation》2021,40(2):787-797
Journal of Plant Growth Regulation - Gibberellins (GAs) are a group of plant hormones that play important roles in various processes. Previous studies demonstrated that GA can increase the... 相似文献
97.
Yuyi Chen Qiudong Yang Chunhua Lv Yue Chen Wenhua Zhao Wenlei Li Hongyu Chen Hua Wang Wen Sun Hua Yuan 《Cell proliferation》2021,54(2)
ObjectivesNLRP3 inflammasome is a critical part of the innate immune system and plays an important role in a variety of inflammatory diseases. However, the effects of NLRP3 inflammasome on periodontitis have not been fully studied.Materials and methodsWe used ligature‐induced periodontitis models of NLRP3 knockout mice (NLRP3KO) and their wildtype (WT) littermates to compare their alveolar bone phenotypes. We further used Lysm‐Cre/RosanTnG mouse to trace the changes of Lysm‐Cre+ osteoclast precursors in ligature‐induced periodontitis with or without MCC950 treatment. At last, we explored MCC950 as a potential drug for the treatment of periodontitis in vivo and in vitro.ResultsHere, we showed that the number of osteoclast precursors, osteoclast differentiation and alveolar bone loss were reduced in NLRP3KO mice compared with WT littermates, by using ligature‐induced periodontitis model. Next, MCC950, a specific inhibitor of the NLRP3 inflammasome, was used to inhibit osteoclast precursors differentiation into osteoclast. Further, we used Lysm‐Cre/RosanTnG mice to demonstrate that MCC950 decreases the number of Lysm‐Cre+ osteoclast precursors in ligature‐induced periodontitis. At last, treatment with MCC950 significantly suppressed alveolar bone loss with reduced IL‐1β activation and osteoclast differentiation in ligature‐induced periodontitis.ConclusionOur findings reveal that NLRP3 regulates alveolar bone loss in ligature‐induced periodontitis by promoting osteoclastic differentiation. 相似文献
98.
99.
Alexandru Paraschiv Thibaut J. Lagny Christian Vanhille Campos Evelyne Coudrier Patricia Bassereau Anđela Šarić 《Biophysical journal》2021,120(4):598-606
The cell membrane is an inhomogeneous system composed of phospholipids, sterols, carbohydrates, and proteins that can be directly attached to underlying cytoskeleton. The protein linkers between the membrane and the cytoskeleton are believed to have a profound effect on the mechanical properties of the cell membrane and its ability to reshape. Here, we investigate the role of membrane-cortex linkers on the extrusion of membrane tubes using computer simulations and experiments. In simulations, we find that the force for tube extrusion has a nonlinear dependence on the density of membrane-cortex attachments: at a range of low and intermediate linker densities, the force is not significantly influenced by the presence of the membrane-cortex attachments and resembles that of the bare membrane. For large concentrations of linkers, however, the force substantially increases compared with the bare membrane. In both cases, the linkers provided membrane tubes with increased stability against coalescence. We then pulled tubes from HEK cells using optical tweezers for varying expression levels of the membrane-cortex attachment protein Ezrin. In line with simulations, we observed that overexpression of Ezrin led to an increased extrusion force, while Ezrin depletion had a negligible effect on the force. Our results shed light on the importance of local protein rearrangements for membrane reshaping at nanoscopic scales. 相似文献
100.