Changes in the cyclic nucleotide level and lysosomal enzyme activity in the gastric mucosa of rats with experimental ulcer formation

The experiments on rats have proved that ulcerative lesions in the gastric mucosa influenced by intraperitoneal catecholamines (noradrenaline and adrenaline) develop on the background of pronounced decrease of cAMP level in the gastric mucosa during ulceration and relatively slight fluctuations of cGMP level. As a result, cAMP/cGMP ratio in mucosa was significantly decreased during ulceration. These changes in cAMP level and cAMP/cGMP ratio may play an important role in destabilization of lysosomal membranes followed by a chain of pathological reactions resulting in ulcerative lesions of the gastric mucosa.     

Effect of pesticides on bacterial membranes

The effect of pure preparation of ordram, fosalon, DDT, methoxychlorine, hydrel, dihydrel, 2,4-D, 2M-4C and of technical preparations of saturn, linuron, ronstar and keltan on the membrane functions (respiration and motility) of Azospirillum brasilense and Chromatium minutissimum cells and on malate and NADH oxidation by the isolated membranes of Micrococcus lysodeikticus was investigated. The effect varied from irreversible impairment to undetectable impairment of the measured activities depending on the type of bacteria and on the chemical used. The ordram induced permeability of the A. brasilense membranes without inhibition of the respiratory chain activity and selective inhibition of malate oxidase accompanied by stimulation of NADH oxidation in the M. lysodeikticus membranes indicates a possibility of ordram application as a regulator of bacterial metabolism.     

Multichannel Nature of Synthesis of Carbon Nanostructures in Low-Temperature Plasma

Plasma Physics Reports - Results of experimental investigation of the influence of C:H ratio in precursor composition on properties of carbon nanostructures synthesized in helium plasma jets are...