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121.
122.
The abundance, frequency of dividing cells and growth ratesof the planktonic cyano bacteria Synechococcus sp. during thesummer of 1995 and 1996 were estimated in the Northwest MediterraneanSea to test whether depth-dependent growth rates of this speciesexplain its dominance in the deep chlorophyll maximum (DCM)layer formed during summer thermal stratification in the NWMediterranean, compared to the surface layer. Abundance at theDCM layer (5070 m) was up to two orders of magnitudegreater than that at the surface, with values ranging from 1.7to 13x106 cells I-1 and from 4 to 175 x 106 cells I-1 at thesurface and in DCM waters, respectively. Gross growth rates,however, were much higher at the surface than in the DCM layer(surface: 0.761.07 day DCM: 0.300.47 day-1 Thehigher gross growth rates at the surface layer were supportedby a higher frequency of dividing cells (surface: 0.090.24;DCM: 0.010.12). The negative correlation between theabundance or standing stock and growth rates of these planktonicpicocyanobacteria points to losses, and not growth rate, asthe main control on the abundance of Synechococcus. Althoughwe provide some evidence that grazing alone may be able to accountfor these losses, further, direct determinations are clearlyneeded to elucidate the regulation of the abundance of Synechococcusin the NW Mediterranean. 相似文献
123.
Leishmaniasis and AIDS co-infection: the Spanish example 总被引:5,自引:0,他引:5
Alvar J 《Parasitology today (Personal ed.)》1994,10(4):160-163
There are an estimated 300 instances of Leishmania/HIV co-infection, of which 200 have occurred in Spain. Jorge Alvar here asks: is there an epidemiological or immunological basis for this high proportion? 相似文献
124.
Resistance to water-vapor diffusion through the skin is thought to be conferred by lipids in the stratum corneum (SC), the outer layer of the epidermis. We tested the effect of ambient humidity on cutaneous water loss (CWL) and lipid composition of the SC by acclimating house sparrows (Passer domesticus) to either a dry (6.5 g/m(3) absolute humidity) or a humid (31 g/m(3)) environment for 3 wk at a thermoneutral temperature (30 degrees C). Sparrows in the dry-acclimated group reduced CWL by 36% compared with those in the humid environment. Relative to initial values, both groups of sparrows decreased CWL, 45% in the dry-acclimated group and 23% in the humid group, suggesting that temperature is also an important stimulus for CWL apart from humidity. Both groups of acclimated sparrows decreased quantities of cholesterol, free fatty acids, and cerebrosides and increased the proportion of ceramides in their SC. Lipid amounts or proportions in the SC did not differ between dry- and humid-acclimated sparrows, but the free fatty acid : ceramide ratio was significantly lower in dry-acclimated birds. Also, lipid composition was only correlated with CWL in dry-acclimated sparrows, suggesting that structural changes to SC lipids are more tightly linked to CWL regulation in response to low humidity. Our results demonstrate phenotypic flexibility in CWL and lipid composition of the SC and provide support for a functional relationship between these traits. 相似文献
125.
126.
Rhea MR Landers DM Alvar BA Arent SM 《Journal of strength and conditioning research / National Strength & Conditioning Association》2003,17(2):303-306
The purpose of this investigation was to examine the effects of the presence of an audience and competition on maximal weight lifting performance. Thirty-two recreationally trained participants (15 men, 17 women; 21 +/- 2.5 years) performed a 1 repetition maximum (1 RM) bench press during 3 different situations (coaction, competitive coaction, and audience condition). Subjects also completed the Activation-Deactivation Adjective Checklist Short Form following the 3 trials to measure arousal state during each of the 3 trials. Significant differences (p < 0.05) were found between competitive coaction and coaction trials as well as between audience and coaction trials. Both men and women demonstrated the highest performance in front of an audience (105 +/- 48 kg) followed by competition (103 +/- 46 kg) and then the coaction trial (93 +/- 43 kg). No significant difference in arousal was measured between trials. The data suggest that performing a maximal lift in the presence of an audience or in competition facilitates performance and support the self-presentation and self-awareness theories. Social facilitation effects should be controlled in research settings and may aid the performance of weight lifting activities during events or competition. 相似文献
127.
Rhea MR Alvar BA Ball SD Burkett LN 《Journal of strength and conditioning research / National Strength & Conditioning Association》2002,16(4):525-529
The purpose of this study was to compare single and multiple sets of weight training for strength gains in recreationally trained individuals. Sixteen men (age = 21 +/- 2.0) were randomly assigned to 1 set (S-1; n = 8) or 3 set (S-3; n = 8) groups and trained 3 days per week for 12 weeks. One repetition maximum (1RM) was recorded for bench press and leg press at pre-, mid-, and posttest. Subjects trained according to daily undulating periodization (DUP), involving the bench press and leg press exercises between 4RM and 8RM. Training intensity was equated for both groups. Analysis of variance with repeated measures revealed statistically significant differences favoring S-3 in the leg press (p < 0.05, effect size [ES] = 6.5) and differences approaching significance in the bench press (p = 0.07, ES = 2.3). The results demonstrate that for recreationally trained individuals using DUP training, 3 sets of training are superior to 1 set for eliciting maximal strength gains. 相似文献
128.
Improved immunogenicity of an immunodominant epitope of the HER-2/neu protooncogene by alterations of MHC contact residues 总被引:3,自引:0,他引:3
Vertuani S Sette A Sidney J Southwood S Fikes J Keogh E Lindencrona JA Ishioka G Levitskaya J Kiessling R 《Journal of immunology (Baltimore, Md. : 1950)》2004,172(6):3501-3508
The HER-2/neu (HER-2) oncogene is expressed in normal epithelial surfaces at low levels and overexpressed in several types of tumors. The low immunogenicity against this self tumor Ag can be improved by developing epitopes with amino acid replacements in their sequences. In this study, three HER-2/neu.369 (HER-2.369) analogue peptides, produced by modifying both anchor positions by introducing L, V, or T at position 2 and V at the C terminus, were analyzed for their capacity to induce CTLs in vitro from human PBMC and in vivo in HLA-A2.1/Kb transgenic mice. One of the analogues (HER-2.369 V2V9) sensitized target cells for HER-2-specific recognition by human CTLs and induced specific CTLs in vitro at 100-fold lower concentrations than the HER-2.369 wild-type epitope. These CTLs were also able to recognize the wild-type epitope and HER-2-expressing tumors in an MHC-restricted manner. Furthermore, a 100-fold lower amount of the HER-2.369 V2V9 analogue compared with the wild-type epitope was required to induce CTLs in HLA-A2.1/Kb transgenic mice. However, the V2V9 analogue demonstrated only marginally better binding to the MHC class I A2 allele compared with wild type. To establish thermodynamic parameters, we developed radiolabeled F3*Y analogues from both the HER-2.369 epitope and the V2V9 analogue. Our results indicate that the high biological activity of the HER-2.369 V2V9 epitope is associated with a slower dissociation kinetic profile, resulting in an epitope with greater HLA-A2 stability. 相似文献
129.
Rhea MR Alvar BA Gray R 《Journal of strength and conditioning research / National Strength & Conditioning Association》2004,18(2):348-352
Accurate correlations between a wide range of physical fitness measures and occupational demands are needed in order to identify specific fitness tests and training needs for firefighters. Twenty professional firefighters performed numerous fitness and job-related performance tests. Pearson product moment correlations were performed to identify the relationship between fitness components and job performance. Significant correlations (p <0.05) with job performance were identified for total fitness (r = -0.62), bench press strength (r = -0.66), hand grip strength (r = -0.71), bent-over row endurance (r = -0.61), bench press endurance (r = -0.73), shoulder press endurance (r = -0.71), bicep endurance (r = -0.69), squat endurance (r = -0.47), and 400-m sprint time (r = 0.79). It is apparent that firefighting taxes virtually all aspects of physical fitness. These data can help the exercise specialist choose appropriate tests and prescribe specific fitness programs for firefighters. Traditional firefighter exercise programs focusing mainly on cardiovascular fitness should be replaced with physical conditioning programs that address all components of fitness. 相似文献
130.
Juan J. Cruz-Motta Patricia Miloslavich Edlin Guerra-Castro Alejandra Hernández-Agreda Cesar Herrera Francisco Barros Sergio A. Navarrete Roger D. Sepúlveda Tim M. Glasby Gregorio Bigatti Maritza Cardenas-Calle Pedro B. M. Carneiro Alvar Carranza Augusto A. V. Flores Patricia Gil-Kodaka Judith Gobin Jorge L. Gutiérrez Eduardo Klein Marcos Krull Juan F. Lazarus Edgardo Londoño-Cruz Tito Lotufo Erasmo C. Macaya Camilo Mora Elba Mora Gabriela Palomo Mirtala Parragué Franciane Pellizzari Roberto Retamales Rosana M. Rocha Leonardo Romero 《Journal of Biogeography》2020,47(9):1966-1979