全文获取类型
收费全文 | 262篇 |
免费 | 17篇 |
出版年
2023年 | 3篇 |
2022年 | 2篇 |
2021年 | 7篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 10篇 |
2017年 | 8篇 |
2016年 | 12篇 |
2015年 | 22篇 |
2014年 | 11篇 |
2013年 | 24篇 |
2012年 | 27篇 |
2011年 | 28篇 |
2010年 | 20篇 |
2009年 | 13篇 |
2008年 | 17篇 |
2007年 | 21篇 |
2006年 | 10篇 |
2005年 | 5篇 |
2004年 | 7篇 |
2003年 | 4篇 |
2002年 | 9篇 |
2001年 | 4篇 |
1998年 | 2篇 |
1997年 | 1篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1993年 | 1篇 |
1989年 | 1篇 |
排序方式: 共有279条查询结果,搜索用时 15 毫秒
101.
102.
Therapeutic concentrations of varenicline in the presence of nicotine increase action potential firing in human adrenal chromaffin cells
下载免费PDF全文
![点击此处可从《Journal of neurochemistry》网站下载免费的PDF全文](/ch/ext_images/free.gif)
103.
Gonzalez-Martinez Alejandro Rodriguez-Sanchez Alejandro Rivadeneyra María Angustias Rivadeneyra Almudena Martin-Ramos Daniel Vahala Riku Gonzalez-Lopez Jesús 《Applied microbiology and biotechnology》2017,101(2):817-829
Applied Microbiology and Biotechnology - A bench-scale granular autotrophic nitrogen removal bioreactor (completely autotrophic nitrogen removal over nitrite (CANON) system) used for the treatment... 相似文献
104.
Nikolay Vassilev Maria Vassileva Rosario Azcon Almudena Medina 《Biotechnology letters》2001,23(2):149-151
Four times higher nodule number was observed when Glomus deserticola (an arbuscular mycorrhizal fungus) was introduced into a soil-plant system as compared to the control inoculated only with Rhizobium trifoli. This symbiotic parameter was further enhanced by Yarowia lipolytica together with an increase in root mycorrhizal infection of about 14%. Soil inoculation with co-encapsulated R. trifoli and Y. lipolytica provoked a 10-fold increase in root nodulation and led to 55% mycorrhization of the test plant. 相似文献
105.
106.
107.
108.
Almudena Ferrández-Ayela Rosa Micol-Ponce Ana Belén Sánchez-García María Magdalena Alonso-Peral José Luis Micol María Rosa Ponce 《PloS one》2013,8(11)
N-α-terminal acetylation is one of the most common, but least understood modifications of eukaryotic proteins. Although a high degree of conservation exists between the N-α-terminal acetylomes of plants and animals, very little information is available on this modification in plants. In yeast and humans, N-α-acetyltransferase complexes include a single catalytic subunit and one or two auxiliary subunits. Here, we report the positional cloning of TRANSCURVATA2 (TCU2), which encodes the auxiliary subunit of the NatB N-α-acetyltransferase complex in Arabidopsis. The phenotypes of loss-of-function tcu2 alleles indicate that NatB complex activity is required for flowering time regulation and for leaf, inflorescence, flower, fruit and embryonic development. In double mutants, tcu2 alleles synergistically interact with alleles of ARGONAUTE10, which encodes a component of the microRNA machinery. In summary, NatB-mediated N-α-terminal acetylation of proteins is pleiotropically required for Arabidopsis development and seems to be functionally related to the microRNA pathway. 相似文献
109.
Epistasis and the temporal change in the additive variance-covariance matrix induced by drift 总被引:3,自引:0,他引:3
López-Fanjul C Fernández A Toro MA 《Evolution; international journal of organic evolution》2004,58(8):1655-1663
The effect of population bottlenecks on the components of the genetic covariance generated by two neutral independent epistatic loci has been studied theoretically (additive, covA; dominance, covD; additive-by-additive, covAA; additive-by-dominance, covAD; and dominance-by-dominance, covDD). The additive-by-additive model and a more general model covering all possible types of marginal gene action at the single-locus level (additive/dominance epistatic model) were considered. The covariance components in an infinitely large panmictic population (ancestral components) were compared with their expected values at equilibrium over replicates randomly derived from the base population, after t consecutive bottlenecks of equal size N (derived components). Formulae were obtained in terms of the allele frequencies and effects at each locus, the corresponding epistatic effects and the inbreeding coefficient Ft. These expressions show that the contribution of nonadditive loci to the derived additive covariance (covAt) does not linearly decrease with inbreeding, as in the pure additive case, and may initially increase or even change sign in specific situations. Numerical examples were also analyzed, restricted for simplicity to the case of all covariance components being positive. For additive-by-additive epistasis, the condition covAt > covA only holds for high frequencies of the allele decreasing the metric traits at each locus (negative allele) if epistasis is weak, or for intermediate allele frequencies if it is strong. For the additive/dominance epistatic model, however, covAt > covA applies for low frequencies of the negative alleles at one or both loci and mild epistasis, but this result can be progressively extended to intermediate frequencies as epistasis becomes stronger. Without epistasis the same qualitative results were found, indicating that marginal dominance induced by epistasis can be considered as the primary cause of an increase of the additive covariance after bottlenecks. For all models, the magnitude of the ratio covAt/covA was inversely related to N and t. 相似文献