全文获取类型
收费全文 | 4397篇 |
免费 | 435篇 |
国内免费 | 1篇 |
出版年
2022年 | 24篇 |
2021年 | 57篇 |
2020年 | 40篇 |
2019年 | 60篇 |
2018年 | 62篇 |
2017年 | 48篇 |
2016年 | 96篇 |
2015年 | 147篇 |
2014年 | 139篇 |
2013年 | 232篇 |
2012年 | 259篇 |
2011年 | 242篇 |
2010年 | 154篇 |
2009年 | 166篇 |
2008年 | 206篇 |
2007年 | 234篇 |
2006年 | 246篇 |
2005年 | 208篇 |
2004年 | 203篇 |
2003年 | 204篇 |
2002年 | 195篇 |
2001年 | 69篇 |
2000年 | 60篇 |
1999年 | 65篇 |
1998年 | 58篇 |
1997年 | 44篇 |
1996年 | 54篇 |
1995年 | 32篇 |
1994年 | 54篇 |
1993年 | 60篇 |
1992年 | 49篇 |
1991年 | 50篇 |
1990年 | 48篇 |
1989年 | 37篇 |
1988年 | 46篇 |
1987年 | 53篇 |
1986年 | 27篇 |
1985年 | 45篇 |
1984年 | 53篇 |
1983年 | 40篇 |
1982年 | 47篇 |
1981年 | 47篇 |
1980年 | 38篇 |
1979年 | 23篇 |
1978年 | 39篇 |
1977年 | 42篇 |
1976年 | 21篇 |
1975年 | 25篇 |
1974年 | 27篇 |
1972年 | 28篇 |
排序方式: 共有4833条查询结果,搜索用时 15 毫秒
951.
Emma?G?theEmail author Allan?Timmermann Kathrin?Januschke Annette?Baattrup-Pedersen 《Hydrobiologia》2016,783(1):79-91
Most river restoration projects have applied relatively small-scale measures focused on improving specific instream conditions, with only limited outcomes for biodiversity in rivers and their adjacent riparian habitats. Here, we investigate the effects of both small- and large-scale restoration projects on floodplain vegetation across 20 European catchments. We focused on the roles of different restoration parameters (i.e., the number, spatial extent and type of restoration measure applied and restoration age) and specific environmental characteristics in regulating changes in plant diversity and trait composition following restoration. Among restoration characteristics, restoration type was the only significant determinant of plant community responses, with stream channel widening having the strongest effects, particularly on the diversity and composition of species traits favoured by increases in physical disturbance (e.g. flooding) and open habitat patch availability (e.g. plant growth form, life strategy and life span). Of the environmental variables, altitude and discharge were positively and most strongly related to responses of both species and trait diversity. Our results emphasise the value of (i) choosing relevant restoration measures that affect environmental conditions of importance for the target organism group and (ii) conducting restoration projects in environmental settings where the likelihood of restoration “success” is maximised. 相似文献
952.
953.
954.
Francy Jimenez-Infante David Kamanda Ngugi Manikandan Vinu Intikhab Alam Allan Anthony Kamau Jochen Blom Vladimir B. Bajic Ulrich Stingl 《Applied and environmental microbiology》2016,82(4):1215-1226
The OM43 clade within the family Methylophilaceae of Betaproteobacteria represents a group of methylotrophs that play important roles in the metabolism of C1 compounds in marine environments and other aquatic environments around the globe. Using dilution-to-extinction cultivation techniques, we successfully isolated a novel species of this clade (here designated MBRS-H7) from the ultraoligotrophic open ocean waters of the central Red Sea. Phylogenomic analyses indicate that MBRS-H7 is a novel species that forms a distinct cluster together with isolate KB13 from Hawaii (Hawaii-Red Sea [H-RS] cluster) that is separate from the cluster represented by strain HTCC2181 (from the Oregon coast). Phylogenetic analyses using the robust 16S-23S internal transcribed spacer revealed a potential ecotype separation of the marine OM43 clade members, which was further confirmed by metagenomic fragment recruitment analyses that showed trends of higher abundance in low-chlorophyll and/or high-temperature provinces for the H-RS cluster but a preference for colder, highly productive waters for the HTCC2181 cluster. This potential environmentally driven niche differentiation is also reflected in the metabolic gene inventories, which in the case of the H-RS cluster include those conferring resistance to high levels of UV irradiation, temperature, and salinity. Interestingly, we also found different energy conservation modules between these OM43 subclades, namely, the existence of the NADH:quinone oxidoreductase complex I (NUO) system in the H-RS cluster and the nonhomologous NADH:quinone oxidoreductase (NQR) system in the HTCC2181 cluster, which might have implications for their overall energetic yields. 相似文献
955.
Patterns of survivorship and growth of rescued boulder corals from two vessel groundings in Biscayne National Park, Homestead, Florida, U.S.A., were evaluated over 5 years and compared to nearby undamaged reference corals. The rescued colonies had been dislodged but reattached in situ 10–12 years later (hereafter termed “restored” corals). Change in live coral tissue area was assessed using novel contoured tissue measurements which proved useful in detecting small changes in tissue area for slow‐growing coral species. At the initial survey, restored boulder corals had a higher level of partial mortality (33.8 ± 3.1%, mean ± SE) relative to reference corals (19.9 ± 2.5%), likely a result of prolonged detachment. During the course of the 5‐year monitoring period, whole‐colony mortality was greater for restored corals (13.1%) compared to reference corals (3.3%). For surviving corals, restored coral growth and recent mortality rates were similar to reference corals even though restored corals, especially those of Dichocoenia stokesii, had greater disease prevalence (19.7%) than reference corals (6.6%). These results suggest that dislodged boulder coral rescue following an acute disturbance can be an effective tool in stemming tissue loss. If dislodged corals were reattached in a more timely manner, we predict that the survival and tissue growth would be greater. 相似文献
956.
Yao Wang Marie K. Hensley Allan Tasman Lonnie Sears Manuel F. Casanova Estate M. Sokhadze 《Applied psychophysiology and biofeedback》2016,41(1):47-60
Autism spectrum disorder (ASD) is a developmental disorder marked by difficulty in social interactions and communication. ASD also often present symptoms of autonomic nervous system (ANS) functioning abnormalities. In individuals with autism the sympathetic branch of the ANS presents an over-activation on a background of the parasympathetic activity deficits, creating an autonomic imbalance, evidenced by a faster heart rate with little variation and increased tonic electrodermal activity. The objective of this study was to explore the effect of 12 sessions of 0.5 Hz repetitive transcranial magnetic stimulation (rTMS) over dorsolateral prefrontal cortex (DLPFC) on autonomic activity in children with ASD. Electrocardiogram and skin conductance level (SCL) were recorded and analyzed during each session of rTMS. The measures of interest were time domain (i.e., R–R intervals, standard deviation of cardiac intervals, NN50-cardio-intervals >50 ms different from preceding interval) and frequency domain heart rate variability (HRV) indices [i.e., power of high frequency (HF) and low frequency (LF) components of HRV spectrum, LF/HF ratio]. Based on our prior pilot studies it was proposed that the course of 12 weekly inhibitory low-frequency rTMS bilaterally applied to the DLPFC will improve autonomic balance probably through improved frontal inhibition of the ANS activity, and will be manifested in an increased length of cardiointervals and their variability, and in higher frequency-domain HRV in a form of increased HF power, decreased LF power, resulting in decreased LF/HF ratio, and in decreased SCL. Our post-12 TMS results showed significant increases in cardiac intervals variability measures and decrease of tonic SCL indicative of increased cardiac vagal control and reduced sympathetic arousal. Behavioral evaluations showed decreased irritability, hyperactivity, stereotype behavior and compulsive behavior ratings that correlated with several autonomic variables. 相似文献
957.
Bruno Ferreira Viana Flávio Oliveira Pires Allan Inoue Dominic Micklewright Tony Meireles Santos 《Applied psychophysiology and biofeedback》2016,41(1):1-7
This study examined the relationship between mood and rating of perceived exertion (RPE) during a simulated multiple-lap time trial (MLTT). Nineteen male cyclists performed a MLTT consisting of four 9.9 km laps, each lap with a gradient ranging from 0 to 10 %. Mood as measured by the Profile of Mood States Questionnaire (POMS) and perceived exertion as measured by the Borg CR100 scale (RPE) were obtained at the end of each lap. A categorical multiple regressive model, having median of POMS subscales as independent variables, was obtained to explain the variance in median RPE responses. Increases in POMS fatigue scores and decreases in POMS vigour scores were observed throughout the MLTT (P < 0.001). A linear increase in RPE during the MLTT was also observed (P < 0.001). POMS fatigue subscale scores accounted for 88 % of the variance in RPE during the MLTT (R2 = 0.88, P = 0.002), and no other POMS subscale improved the final predictive model. With the exception of fatigue these results suggest that most aspects of mood do not have a discernable effect on RPE during a MLTT. The rate of increase in RPE can predict the MLTT endpoint. 相似文献
958.
Thabiso N. Tshabalala Mihai-Silviu Tomescu Allan Prior Vijayakumar Balakrishnan Yasien Sayed Heini W. Dirr Ikechukwu Achilonu 《The protein journal》2016,35(6):448-458
The energetics of ligand binding to human eukaryotic elongation factor 1 gamma (heEF1γ) was investigated using reduced glutathione (GSH), oxidised glutathione (GSSG), glutathione sulfonate and S-hexylglutathione as ligands. The experiments were conducted using isothermal titration calorimetry, and the findings were supported using computational studies. The data show that the binding of these ligands to heEF1γ is enthalpically favourable and entropically driven (except for the binding of GSSG). The full length heEF1γ binds GSSG with lower affinity (K d = 115 μM), with more hydrogen-bond contacts (ΔH = ?73.8 kJ/mol) and unfavourable entropy (?TΔS = 51.7 kJ/mol) compared to the glutathione transferase-like N-terminus domain of heEF1γ, which did not show preference to any specific ligand. Computational free binding energy calculations from the 10 ligand poses show that GSSG and GSH consistently bind heEF1γ, and that both ligands bind at the same site with a folded bioactive conformation. This study reveals the possibility that heEF1γ is a glutathione-binding protein. 相似文献
959.
Changes in neural responsivity to highly palatable foods following roux‐en‐Y gastric bypass,sleeve gastrectomy,or weight stability: An fMRI study
下载免费PDF全文
![点击此处可从《Obesity (Silver Spring, Md.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
960.
Allan Inoue Franco M. Impellizzeri Flávio O. Pires Fernando A. M. S. Pompeu Andrea C. Deslandes Tony M. Santos 《PloS one》2016,11(1)