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排序方式: 共有639条查询结果,搜索用时 15 毫秒
631.
A. G. Globa Ya. I. Alekseev V. G. Arzumanyan V. A. Zaborova A. A. Guridov 《Biochemistry (Moscow) Supplemental Series B: Biomedical Chemistry》2013,7(2):175-177
A test system has been developed for determination of propionic bacterial species inhabiting the human skin. This system developed in the real time PCR format is applicable for quantitative determination and also detection of genomes of the following Propionibacterium species: P. acnes, P. granulosum, and P. avidum. This system was used for analysis of wash samples from the skin of 17 pentathlon sportsmen and 16 students. All three species of propionic bacteria were found in all skin wash samples. However, contamination with P. acnes was two times higher in the control group than in the group of pentathlon sportsmen. 相似文献
632.
A N Alekseev 《Parazitologiia》1989,23(2):89-97
The author has reviewed the available literature on the changes in the physiological state and behaviour of hosts of vector-borne diseases agents during the before-host-changing and during host-changing periods. For vertebrates the effect of the agent is reflected in the rise of body temperature, reduction of locomotor activity and protective reactions, thrombocytopenia and vasodilation, accompanied by periodical concentration of the agent in the peripheral part of the vascular system. All this provides a successful search for a host, a source of infection, and obtaining the agent by blood-sucking vector. For arthropods the effect of the agent is reflected in changes in the vector behaviour as during the host-searching period so in an attempt for bloodsucking. Alimentary tract obstruction with an agent blocking, phagoreceptors block (eructation type of infection), inhibition of saliva ferments activity (saliva type of transmission) result in the prolongation of the feeding period and rise of agent hit probability. The last three types of effect on the feeding mechanism increase the possibility of death of an infected individual and decrease the chance of progeny preservation. 相似文献
633.
Victor Alekseev 《Hydrobiologia》2000,417(1):57-79
Morphological characters useful for taxonomic identification of older copepodid instars of the subfamily Eucyclopinae were studied among 14 species of Eucyclops, Macrocyclops, Ectocyclops, Paracyclops and Tropocyclops known from European Russia. For taxonomic analysis, the following elements of copepodid morphology were chosen: armament and proportion of furcal rami; morphology of swimming legs and reduced 5th and 6th legs; antennule segmentation; and relative body length of copepodid instars in comparison with the female length. Changes in morphology of major copepodid instars of the subfamily Eucyclopinae during ontogenetic development are traced and noticeable differences among five genera and 14 species are described. These differences among major copepodid stages may be important for both taxonomic and ecological analysis. For taxonomy, they provide information on development of sexes and species during maturation. For ecology they allow identification of the specimens at 4–5 copepodid instars in diapause. A key to major copepodid instars of the species from the subfamily Eucyclopinae which are known from limnetic habitats of the European part of Russia is presented. 相似文献
634.
The present notions on the metabolism of methylglyoxal, an endogenic controller of cellular proliferation, are adduced. The interaction between metabolism of methylglyoxal and that of carbohydrates, proteins and lipids is demonstrated. The metabolic chart has been worked out and enzymes catalyzing methylglyoxal metabolic reactions are determined. The effect of methylglyoxal and its bisguanylhydrazones derivatives on the processes of cellular proliferation control has been examined. 相似文献
635.
A N Alekseev 《Parazitologiia》1985,19(1):3-7
An attempt has been made to relate the ability of bloodsucking arthropods to be specific vectors of different groups of agents to such properties of digestive system of blood-suckers as the type of food consumption on larval and imaginal phases, composition of food consumed by larva and imago, structure of intestinal epithelium in adult arthropods and speed of blood digestion process. 相似文献
636.
S B Alekseev V B Mamaev L G Stepanova L I Kalinina A N Avakova 《Biokhimii?a (Moscow, Russia)》1979,44(5):940-946
A new procedure for purification of glucose-6-phosphate dehydrogenase resulting in an electrophoretically homogenous preparation made up of 5.10(8) cells (390 mg of protein) is proposed. The enzyme yield is more than 20%. The molecular weights of a subunit and a native enzyme are 55000 and 220000, respectively. The isoelectric point for the protein lies at 4,8. The kinetics of the enzyme thermal inactivation obey the first order equation with the inactivation rate constant of 6.10(-3) min-1. 相似文献
637.
Bases and spaces: resources on the web for accessing the draft human genome - II - After publication of the draft 下载免费PDF全文
Colin AM Semple 《Genome biology》2001,2(6):reviews2001.1-reviews20016
The volume of human genome sequence and the variety of web-based tools to access it continue to grow at an impressive rate, but a working knowledge of certain key resources can be sufficient to get the most from your genome. This article provides an update to Genome Biology 2000, 1(4):reviews2001.1-2001.5. 相似文献
638.
A. N. Alekseev 《Journal of Evolutionary Biochemistry and Physiology》2007,43(6):603-619
Coevolutionary relationships of ticks of the Ixodes genus with causative agents pathogenic for human of viral, bacterial, and protozoan nature are considered using the method of polymerase chain reaction (PCR). Peculiarities of genotypic composition of ticks-vectors are analyzed, which differ in malate dehydrogenase and of which alleles are investigated by the polyacrylamide gel electrophoresis method. The inherited phenotypic differences of population composition of 2 tick species of the Ixodes genus differing by the presence of exoskeleton anomalies and the content of ions of heavy metals-pollutants accumulated in the tick body are investigated. The character of interaction of various tick-borne pathogens in the tick body and the degree of danger of these tocks depending on geno-and phenotypic properties of the populations throughout their area are determined. 相似文献
639.
S B Alekseev V B Mamaev L G Stepanova L I Kalinina O G Andzhaparidze 《Biokhimii?a (Moscow, Russia)》1979,44(7):1251-1255
The thermal inactivation kinetics of glucose-6-phosphate dehydrogenase during ageing of human diploid cells were studied. It was shown that semi-logarithmic anamorphisms of the thermal inactivation kinetic curves may be presented as a total of two rectilinear sites corresponding to the thermolabile and thermostable fractions of the enzyme. In ageing cells the enzyme stability is decreased as compared to the young ones due to the increase in the amount of the thermolabile fraction. It was also found that despite a certain variability in the process of the cell growth at the 22nd passage the thermal stability of glucose-6-phosphate dehydrogenase is decreased, while the enzyme thermal stability in the cells at the 52nd passage is monotonously increased. Purification of the enzyme from ageing and young human diploid cells results in an increase of the enzyme stability. However, when the enzyme was isolated from young cells, it possessed a higher thermal stability. 相似文献