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排序方式: 共有180条查询结果,搜索用时 15 毫秒
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Sekikawa A Steingrimsdottir L Ueshima H Shin C Curb JD Evans RW Hauksdottir AM Kadota A Choo J Masaki K Thorsson B Launer LJ Garcia ME Maegawa H Willcox BJ Eiriksdottir G Fujiyoshi A Miura K Harris TB Kuller LH Gudnason V 《Prostaglandins, leukotrienes, and essential fatty acids》2012,87(1):11-16
In the 1990s Iceland and Japan were known as countries with high fish consumption whereas coronary heart disease (CHD) mortality in Iceland was high and that in Japan was low among developed countries. We described recent data fish consumption and CHD mortality from publicly available data. We also measured CHD risk factors and serum levels of marine-derived n-3 and other fatty acids from population-based samples of 1324 men in Iceland, Japan, South Korea, and the US. CHD mortality in men in Iceland was almost 3 times as high as that in Japan and South Korea. Generally, a profile of CHD risk factors in Icelanders compared to Japanese was more favorable. Serum marine-derived n-3 fatty acids in Iceland were significantly lower than in Japan and South Korea but significantly higher than in the US. 相似文献
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A sand fly fossil was found in amber; a vegetal resin, which allows all the external phlebotomine structures to be seen. The piece that contains the new species is 14 mm long x 8 mm wide x 3 mm high. All the structures from the head, thorax, and abdomen were examined under the microscope and measured with a calibrated micrometric eyepiece. The morphological aspects of the new species suggest its inclusion in the Pintomyia genus, Pifanomyia subgenus though it is not possible to include it in any of the series known for this subgenus. The presence of two atrophied spines on the gonostyles and gonocoxites without tufts of setae permit the exclusion of the new species from the other species of the subgenus Pifanomyia. The new species is named Pintomyia (Pifanomyia) brazilorum sp. nov. 相似文献
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Osiro D Colnago LA Otoboni AM Lemos EG de Souza AA Coletta Filho HD Machado MA 《FEMS microbiology letters》2004,236(2):313-318
Xylella fastidiosa is the causal agent of citrus variegated chlorosis and Pierce's disease which are the major threat to the citrus and wine industries. The most accepted hypothesis for Xf diseases affirms that it is a vascular occlusion caused by bacterial biofilm, embedded in an extracellular translucent matrix that was deduced to be the exopolysaccharide fastidian. Fourier transform infrared spectroscopy analysis demonstrated that virulent cells which form biofilm on glass have low fastidian content similar to the weak virulent ones. This indicates that high amounts of fastidian are not necessary for adhesion. In this paper we propose a kinetic model for X. fastidiosa adhesion, biofilm formation, and virulence based on electrostatic attraction between bacterial surface proteins and xylem walls. Fastidian is involved in final biofilm formation and cation sequestration in dilute sap. 相似文献
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The fungal cultivar of leaf‐cutter ants produces specific enzymes in response to different plant substrates 下载免费PDF全文
Lily Khadempour Kristin E. Burnum‐Johnson Erin S. Baker Carrie D. Nicora Bobbie‐Jo M. Webb‐Robertson Richard A. White III Matthew E. Monroe Eric L. Huang Richard D. Smith Cameron R. Currie 《Molecular ecology》2016,25(22):5795-5805
Herbivores use symbiotic microbes to help derive energy and nutrients from plant material. Leaf‐cutter ants are a paradigmatic example, cultivating their mutualistic fungus Leucoagaricus gongylophorus on plant biomass that workers forage from a diverse collection of plant species. Here, we investigate the metabolic flexibility of the ants’ fungal cultivar for utilizing different plant biomass. Using feeding experiments and a novel approach in metaproteomics, we examine the enzymatic response of L. gongylophorus to leaves, flowers, oats or a mixture of all three. Across all treatments, our analysis identified and quantified 1766 different fungal proteins, including 161 putative biomass‐degrading enzymes. We found significant differences in the protein profiles in the fungus gardens of subcolonies fed different plant substrates. When provided with leaves or flowers, which contain the majority of their energy as recalcitrant plant polymers, the fungus gardens produced more proteins predicted to break down cellulose: endoglucanase, exoglucanase and β‐glucosidase. Further, the complete metaproteomes for the leaves and flowers treatments were very similar, while the mixed substrate treatment closely resembled the treatment with oats alone. This indicates that when provided a mixture of plant substrates, fungus gardens preferentially break down the simpler, more digestible substrates. This flexible, substrate‐specific enzymatic response of the fungal cultivar allows leaf‐cutter ants to derive energy from a wide range of substrates, which likely contributes to their ability to be dominant generalist herbivores. 相似文献
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José Angelo Lindoso Gláucia Fernandes Cota Alda Maria da Cruz Hiro Goto Ana Nilce Silveira Maia-Elkhoury Gustavo Adolfo Sierra Romero Márcia Leite de Sousa-Gomes Joanna Reis Santos-Oliveira Ana Rabello 《PLoS neglected tropical diseases》2014,8(9)
Visceral leishmaniasis (VL) is an endemic zoonotic disease in Latin America caused by Leishmania (Leishmania) infantum, which is transmitted by sand flies from the genus Lutzomyia. VL occurs in 12 countries of Latin America, with 96% of cases reported in Brazil. Recently, an increase in VL, primarily affecting children and young adults, has been observed in urban areas of Latin America. The area in which this spread of VL is occurring overlaps regions with individuals living with HIV, the number of whom is estimated to be 1.4 million people by the World Health Organization. This overlap is suggested to be a leading cause of the increased number of reported VL-HIV coinfections. The clinical progression of HIV and L. infantum infections are both highly dependent on the specific immune response of an individual. Furthermore, the impact on the immune system caused by either pathogen and by VL-HIV coinfection can contribute to an accelerated progression of the diseases. Clinical presentation of VL in HIV positive patients is similar to patients without HIV, with symptoms characterized by fever, splenomegaly, and hepatomegaly, but diarrhea appears to be more common in coinfected patients. In addition, VL relapses are higher in coinfected patients, affecting 10% to 56.5% of cases and with a lethality ranging from 8.7% to 23.5% in Latin America, depending on the study. With regards to the diagnosis of VL, parasitological tests of bone marrow aspirates have proven to be the most sensitive test in HIV-infected patients. Serologic tests have demonstrated a variable sensitivity according to the method and antigens used, with the standard tests used for diagnosing VL in Latin America displaying lower sensitivity. For this review, few articles were identified that related to VL-HIV coinfections and originated from Latin America, highlighting the need for improving research within the regions most greatly affected. We strongly support the formation of a Latin American network for coinfections of Leishmania and HIV to improve the consistency of research on the current situation of VL-HIV coinfections. Such a network would improve the collection of vital data and samples for better understanding of the clinical manifestations and immunopathogenic aspects of VL in immunosuppressed patients. Ultimately, a concerted effort would improve trials for new diagnostic methodologies and therapeutics, which could accelerate the implementation of more specific and effective diagnosis as well as public policies for treatments to reduce the impact of VL-HIV coinfections on the Latin American population. 相似文献
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Fernando Alda Manuel A. González Pedro P. Olea Vicente Ena Raquel Godinho Sergei V. Drovetski 《European Journal of Wildlife Research》2013,59(5):719-728
Populations at the rear edge of the species’ range are often at a high risk of extinction due to their isolation, fragmentation and small population sizes. However, these populations also play a relevant role in the conservation of biodiversity since they may represent a valuable genetic resource. The endangered Cantabrian Capercaillie (Tetrao urogallus cantabricus) inhabits deciduous forests of the Cantabrian Mountains of Spain, at the southwestern limit of the species’ range. Recently, nine Cantabrian Capercaillie leks were discovered in Pyrenean oak forests of the southern slope of the Cantabrian range, where the subspecies historically occurred. To elucidate if the origin of this peripheral population nucleus is the result of a historical range contraction or a recent re-colonization from the core population, we sampled moulted feathers from all the known leks in the southern peripheral forests and from the adjacent main core population, based on nine microsatellite loci genotypes. No significant genetic differentiation was detected between main core and peripheral forests suggesting that gene flow is not interrupted between these nuclei. Contrary to expected, peripheral forests did not represent sink populations, since gene flow mainly occurred from southern peripheral to northern main core forests. Therefore, the origin of these birds inhabiting the peripheral nucleus seems not to be a recent colonization but relicts from the former distribution range that have remained unnoticed in a drier and warmer environment than described so far for the species. Cantabrian Capercaillie faces a high risk of extinction in the southernmost forests of its distribution, not only because of its peripheral location but also due to its small population size, low genetic diversity and low incoming gene flow. According to our results, this peripheral nucleus could represent an expanding edge for the population if Pyrenean oak forests continue to spread out southwards and consequently stress the need for conservation programs to preserve habitat availability and forest connectivity. 相似文献
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