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101.
Summary
Sheep plasma α1 -protease inhibitor (PI1) variants were typed by analysing neuraminidase treated samples by isoelectric focusing in ultra-thin polyacrylamide gels followed by staining for trypsin inhibition. The 10 different PI1 pheno-types observed were shown to be controlled by four codominant alleles. The probability of sire exclusion provided by PI1 polymorphism was about 0.45 in both of the studied milk sheep breeds (Latxa and Karrantzar) of the Basque Country. 相似文献
Sheep plasma α
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103.
104.
Lactic acid bacteria and human clinical infection 总被引:3,自引:0,他引:3
105.
Luis Miguel Rondón García Blanca Aranzazu Aguirre Arizala Francisco José García García 《Revista espa?ola de geriatría y gerontología》2018,53(5):268-273
Introduction
This study presents an analysis on the effects of positive social relationships as determining factors on the health status of the elderly, from an interdisciplinary point of view.Materials and methods
A survey was carried out on a total of 2,332 subjects in the province of Toledo, Spain, using several scales related to the study objectives. For the multivariable analysis of the data, the linear regression, along with goodness of fit, as well as the tests of Cox, Snell and R-squared of Nagelkerke, were calculated to determine the correlation between the networks and the social contacts with the health.Results
Good social relationships result in better health, because they allow us to feel good and add life to the years. The size of the social network, and the frequency of contacts, although decreasing with age, become vitally important at this stage of life. All these factors constitute stimuli to improve the perception of health, to provide social support in activities of daily living, as well as for instrumental or disease management.Conclusions
The main outcome of this study is that positive social relationships can be considered as a determining factor in the health of the elderly, but not all these interactions influence the same extent. The factor of the human relationship in terms of emotional proximity, together with the frequency or quantity of these encounters, are also correlated with health, due to the emotional impact they imply. 相似文献106.
Steven D. Fidanze Dachun Liu Robert A. Mantei Lisa A. Hasvold John K. Pratt George S. Sheppard Le Wang James H. Holms Yujia Dai Ana Aguirre Andrew Bogdan Justin D. Dietrich Jasmina Marjanovic Chang H. Park Charles W. Hutchins Xiaoyu Lin Mai H. Bui Xiaoli Huang Keith F. McDaniel 《Bioorganic & medicinal chemistry letters》2018,28(10):1804-1810
Novel conformationally constrained BET bromodomain inhibitors have been developed. These inhibitors were optimized in two similar, yet distinct chemical series, the 6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-ones (A) and the 1-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-ones (B). Each series demonstrated excellent activity in binding and cellular assays, and lead compounds from each series demonstrated significant efficacy in in vivo tumor xenograft models. 相似文献
107.
Milholland Matthew T. Castro-Arellano Iván Suzán Gerardo Garcia-Peña Gabriel E. Lee Thomas E. Rohde Rodney E. Alonso Aguirre A. Mills James N. 《EcoHealth》2018,15(1):163-208
EcoHealth - Rodents represent 42% of the world’s mammalian biodiversity encompassing 2,277 species populating every continent (except Antarctica) and are reservoir hosts for a wide diversity... 相似文献
108.
High site fidelity and restricted ranging patterns in southern Australian bottlenose dolphins
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Cecilia Passadore Luciana Möller Fernando Diaz‐Aguirre Guido J. Parra 《Ecology and evolution》2018,8(1):242-256
Information on site fidelity and ranging patterns of wild animals is critical to understand how they use their environment and guide conservation and management strategies. Delphinids show a wide variety of site fidelity and ranging patterns. Between September 2013 and October 2015, we used boat‐based surveys, photographic identification, biopsy sampling, clustering analysis, and geographic information systems to determine the site‐fidelity patterns and representative ranges of southern Australian bottlenose dolphins (Tursiops cf. australis) inhabiting the inner area of Coffin Bay, a highly productive inverse estuary located within Thorny Passage Marine Park, South Australia. Agglomerative hierarchical clustering (AHC) of individuals’ site‐fidelity index and sighting rates indicated that the majority of dolphins within the inner area of Coffin Bay are “regular residents” (n = 125), followed by “occasional residents” (n = 28), and “occasional visitors” (n = 26). The low standard distance deviation indicated that resident dolphins remained close to their main center of use (range = 0.7–4.7 km, X ± SD = 2.3 ± 0.9 km). Representative ranges of resident dolphins were small (range = 3.9–33.5 km2, X ± SD = 15.2 ± 6.8 km2), with no significant differences between males and females (Kruskal–Wallis, χ2 = 0.426, p = .808). The representative range of 56% of the resident dolphins was restricted to a particular bay within the study area. The strong site fidelity and restricted ranging patterns among individuals could be linked to the high population density of this species in the inner area of Coffin Bay, coupled with differences in social structure and feeding habits. Our results emphasize the importance of productive habitats as a major factor driving site fidelity and restricted movement patterns in highly mobile marine mammals and the high conservation value of the inner area of Coffin Bay for southern Australian bottlenose dolphins. 相似文献
109.
Amelia A. Langston Cathryn S. Mellersh Cassandra L. Neal Kunal Ray Gregory M. Acland Mark Gibbs Gustavo D. Aguirre R.E.K. Fournier Elaine A. Ostrander 《Genomics》1997,46(3):317
We have constructed a collection of canine–rodent microcell hybrid cell lines by fusion of canine fibroblast microcell donors with immortalized rodent recipient cells. Characterization of the hybrid cell lines using a combination of fluorescencein situhybridization and PCR analysis of canine microsatellite repeat sequences allowed selection of a panel of hybrids in which most canine chromosomes are represented. Approximately 90% of genetic markers and genes that were tested could be assigned to 1 of 31 anonymous canine chromosome groups, based on common patterns of retention in the hybrid set. Many of these putative chromosome groups have now been validated by linkage analysis. This panel of cell lines provides a tool for development of genetic, physical, and comparative maps of the canine genome. 相似文献
110.