腺嘌呤与氢化可的松大鼠肾阳虚模型造模方法比较

目的比较腺嘌呤诱导与氢化可的松诱导的SD大鼠肾阳虚模型的优劣,从而得到临床症状、生化指标更符合中医“肾阳虚”型的动物模型,以供科研、教学使用。方法雄性SD大鼠100只,随机分成正常组、腺嘌呤造模组及氢化可的松低剂量组、中剂量组、高剂量组各20只,造模成功后检测血肌酐（Scr）、尿素氮（BUN）、尿液中17-羟皮质类固醇（17-OH）和血浆中甲状腺激素（13、T4）、睾丸酮（T）、雌二醇（E2）及模型大鼠骨密度。结果无论从症状主证方面,还是客观指标方面（除骨密度外）,腺嘌呤诱导的SD大鼠肾阳虚型动物模型在生化指标研究方面均优于氢化可的松诱导组。结论腺嘌呤诱导的肾阳虚证SD大鼠模型在症状主证方面及其相关的生化研究方面优于氢化可的松组。     

ERRATUM: Effects of Loading on the Biomechanical Behavior of Molars of Homo,Pan, and Pongo. Am J Phys Anthropol 109:211–227.

ERRATUM: Macho GA and Spears IR. 1999. Effects of Loading on the Biomechanical Behavior of Molars of Homo, Pan, and Pongo. Am J Phys Anthropol 109:211–227. The correct title of the article is given above. The word “biochemical” should be read as “biomechanical.”     

肿瘤干细胞研究进展及临床应用前景

肿瘤干细胞是肿瘤中具有自我更新能力和分化潜能,能产生异质性细胞的细胞。我们简要阐述了肿瘤干细胞存在的证据、分离技术及来源,并对以肿瘤干细胞为靶标的肿瘤治疗途径、临床应用前景和问题进行了综述。     

缟蝇科昆虫生物学和地理分布分析

本文概述了缟蝇科昆虫的生活史、食性、访花习性、栖居环境等生物学特性,并对缟蝇科属、种的地理分布进行了分析。缟蝇科在世界动物地理区的分布统计结果表明,同脉缟蝇亚科为亚世界性分布,其属级阶元在东洋界丰富度最高,其次为澳洲界;其种级阶元在东洋界最为丰富,其次为澳洲界。缟蝇亚科为世界性分布,其属级阶元在新热带界丰富度最高,并且高度特化,其次是东洋界和澳洲界;其种级阶元在新热带界最为丰富,其次为古北界和澳洲界。缟蝇科在中国动物地理区和亚区的分布统计结果显示,其属、种级阶元在华南区最为丰富;同脉缟蝇亚科的种级阶元以海南岛亚区最为丰富,其次为台湾亚区;缟蝇亚科的种级阶元在台湾亚区最为丰富,西部山地高原亚区次之。     

Biological characteristics of Proteus strains isolated from water sources in the Azerbajiani SSR]

Biological characteristics of 102 Proteus strains isolated from the water bodies is given. The strains studied were referred to Pr. mirabilis, more rarely to Pr. vulgaris; about half of the cultures deviated from these biological types by the signs of indol formation and maltose fermentation. Proteus of groups O3, O5, O13, O23, and O30 were revealed in studying the serological characteristics. All the cultures were polyresistant, nonbacteriocinogenic; most of them were sensitive to the wide colicine spectrum. One strain produced a cytopathogenic action on the tissue culture.     

一株石油降解菌培养基的优化

目的：有效降低石油降解菌株CT-6在工业生产中的培养成本,提高培养速度。方法：利用Minitab软件,采用中心组合设计、响应面分析,以葡萄糖、蔗糖、可溶性淀粉为碳源,以硝酸铵、尿素、氯化铵为氮源,对高效降解石油菌株CT-6的培养基进行了优化。结果：当碳源葡萄糖为5.6818g/L、氮源氯化铵为3.8030g/L时,菌株CT-6培养17h,OD600达到0.615。结论：优化前后,菌体CT-6的OD600分别为0.289和0.615,提高了112.8%,说明该培养基更有利于菌株CT-6的生长。     

Lead-phase and red-stripe color morphs of red-backed salamanders Plethodon cinereus differ in hematological stress indices: A consequence of differential predation pressure?

Throughout the animal kingdom there are species that have two or more phenotypic forms or 'morphs', and many of these are amphibians. In North America, the red-backed salamander Plethodon cinereus can have either a red dorsal stripe or no dorsal stripe (lead-phase form), and evidence to date indicates the lead-phase form incurs a greater number of attacks from predators. In a recent collection of 51 P. Cinereus, blood smears of both color morphs (35 red-stripe, 16 lead-phase) were examined to obtain numbers of circulating leukocytes (via light microscopy), which can be used to indirectly estimate levels of stress hormones in vertebrates via a 'hematological stress index', which is the ratio between the number of two leukocyte types (neutrophils and lymphoeytes). Our results showed that lead-phase salamanders tended to have greater numbers of circulating neutrophils and lower numbers of circulating iymphocytes than red-stripe morphs, leading to higher average neutrophil-lymphocyte ratios in lead-phase individuals. Since the salamanders were held (refrigerated) for 7 days before sampling, we cannot be certain if this effect is a stress reaction to the captivity or the normal level for this morph. However comparison with two sets of related salamanders that were captured and sampled immediately indicates the red-stripe salamanders were either not stressed from the captivity at all, or their white blood cell distributions had returned to normal after 7 days of captivity. Taken together, our results indicate that lead-phase forms of P. Cinereus have higher stress levels than the red-stripe forms, which may be a consequence of their higher exposure to, and/or attacks from, predators. They may also indicate that the lead-phase form is less-suited to captivity than the red-stripe form of this species.