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121.
122.
Peter A. Abrams 《Evolutionary ecology》1997,11(6):673-686
The evolutionary responses of predators to prey and of prey to predators are analysed using models for the dynamics of a quantitative trait that determines the capture rate of prey by an average searching predator. Unlike previous investigations, the analysis centres on models and/or parameter values for which the two-species equilibrium is locally unstable. The instability in some models is driven by the predators non-linear functional response to prey; in other models, the cycles are a direct consequence of evolutionary response to selection acting on the trait. When the values of predator and prey traits combine multiplicatively to determine the capture rate, the predators trait shows only a transient response to changes in the preys trait in stable systems. However, when the population densities exhibit sustained oscillations, predators often evolve an increased long-term mean capture rate in response to an increased prey escape ability. Under the multiplicative model, prey in stable systems always evolve increased escape ability in response to an increased predator capture a 相似文献
123.
The preparation and characterization of dichloro- (hydrotris(1-pyrazolyl)borato)pyridinechromium(III), CrCl2(HB(PYZ)3)Py, (Py = pyridine and HB(PYZ)3-1 is the hydrotris(1-pyrazolyl)borato anion) is described. The structure of the compound was determined by single crystal X-ray diffraction. Crystals were monoclinic, P21/c, a = 11.603(2), b = 9.845(1), c = 16.095(2) Å, β = 96.04(1)° with four formula units in the unit cell. Intensities were measured on a Nicolet P3 diffractometer with use of Mokα radiation. The structure was solved by standard methods and refined to R1 = 0.0601, R2 = 0.0397 based on 3142 independent reflections. Bond lengths and angles are normal. The pyridine molecule is oriented such that the plane bisects the angle between the two cis pyrazole rings. The synthesis and preparation of the related Cr(III) species CrCl2(HB(PYZ)3)pyrazole, Ph4As[CrCl3HB(PYZ)3] and [Cr(HB(PYZ)3)2]PF6 are described and the evaluation of the CrCl2(HB(PYZ)3)L (L = pyridine or pyrazole) species for genotoxicity is discussed. 相似文献
124.
125.
John M. Fryxell John F. Wilmshurst Anthony R. E. Sinclair Daniel T. Haydon Robert D. Holt Peter A. Abrams 《Ecology letters》2005,8(3):328-335
Species persistence can be threatened by substantial temporal variation in food resources over time. On the other hand, spatial heterogeneity in resources at the landscape scale might allow mobile consumers to compensate for temporal variability in resource availability at the local scale. We evaluated this hypothesis, using an extensive data set on foraging, grass growth, and movement by Thomson's gazelles living on the Serengeti Plains. Here we show that modelled populations of Thomson's gazelles can only persist under Serengeti conditions in the face of observed levels of rainfall stochasticity by making adaptive movements to take advantage of ephemeral spatial distributions of food resources. More importantly, our models suggest that Thomson's gazelles in Serengeti require unrestricted access to relatively large areas of grassland (> 1600 km2) to guarantee long‐term persistence, particularly when there is positive spatial autocorrelation in resource abundance, as is the case in Serengeti. If this proves to be true for other species and/or other systems, then understanding of complex behavioural responses to spatially and temporally heterogeneous food supplies may be essential to successful conservation of grazing herbivores. 相似文献
126.
Inhibitory action of carbodiimides on bacterial membrane ATPase 总被引:4,自引:0,他引:4
127.
Interaction of naphthaleneacetic Acid and kinetin in the senescence of detached leaves 总被引:3,自引:3,他引:0
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Kinetin and naphthaleneacetic acid were applied separately and in combination to excised leaf disks, localized areas of laminae, and petioles of detached leaves of broccoli (Brassica oleracea L., var. italica) and Xanthium (Xanthium pensylvanicum Wallr.). Senscence (measured as loss of chlorophyll) was strongly retarded by kinetin, but very slightly influenced by naphthaleneacetic acid. When the 2 substances were applied concurrently, the effect of kinetin was markedly reduced by naphthalene acetic acid. Neither interference with uptake nor transport of kinetin appeared to cause the reduction. 相似文献
128.
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance 总被引:16,自引:0,他引:16
McCubrey JA Steelman LS Chappell WH Abrams SL Wong EW Chang F Lehmann B Terrian DM Milella M Tafuri A Stivala F Libra M Basecke J Evangelisti C Martelli AM Franklin RA 《Biochimica et biophysica acta》2007,1773(8):1263-1284
Growth factors and mitogens use the Ras/Raf/MEK/ERK signaling cascade to transmit signals from their receptors to regulate gene expression and prevent apoptosis. Some components of these pathways are mutated or aberrantly expressed in human cancer (e.g., Ras, B-Raf). Mutations also occur at genes encoding upstream receptors (e.g., EGFR and Flt-3) and chimeric chromosomal translocations (e.g., BCR-ABL) which transmit their signals through these cascades. Even in the absence of obvious genetic mutations, this pathway has been reported to be activated in over 50% of acute myelogenous leukemia and acute lymphocytic leukemia and is also frequently activated in other cancer types (e.g., breast and prostate cancers). Importantly, this increased expression is associated with a poor prognosis. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. For example, in some cells, PTEN mutation may contribute to suppression of the Raf/MEK/ERK cascade due to the ability of activated Akt to phosphorylate and inactivate different Rafs. Although both of these pathways are commonly thought to have anti-apoptotic and drug resistance effects on cells, they display different cell lineage specific effects. For example, Raf/MEK/ERK is usually associated with proliferation and drug resistance of hematopoietic cells, while activation of the Raf/MEK/ERK cascade is suppressed in some prostate cancer cell lines which have mutations at PTEN and express high levels of activated Akt. Furthermore the Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways also interact with the p53 pathway. Some of these interactions can result in controlling the activity and subcellular localization of Bim, Bak, Bax, Puma and Noxa. Raf/MEK/ERK may promote cell cycle arrest in prostate cells and this may be regulated by p53 as restoration of wild-type p53 in p53 deficient prostate cancer cells results in their enhanced sensitivity to chemotherapeutic drugs and increased expression of Raf/MEK/ERK pathway. Thus in advanced prostate cancer, it may be advantageous to induce Raf/MEK/ERK expression to promote cell cycle arrest, while in hematopoietic cancers it may be beneficial to inhibit Raf/MEK/ERK induced proliferation and drug resistance. Thus the Raf/MEK/ERK pathway has different effects on growth, prevention of apoptosis, cell cycle arrest and induction of drug resistance in cells of various lineages which may be due to the presence of functional p53 and PTEN and the expression of lineage specific factors. 相似文献
129.
Models of two independent host populations and a common parasitoid are investigated. The hosts have density-dependent population growth and only interact indirectly by their effects on parasitoid behavior and population dynamics. The parasitoid is assumed to experience a trade-off in its ability to exploit the two hosts. Three alternative types of parasitoid are investigated: (i) fixed generalists whose consumption rates are those that maximize fitness; (ii) “ideal free” parasitoids, which modify their behavior to maximize their rate of finding unparasitized hosts within a generation; and (iii) “evolving” parasitoids, whose capture rates change between generations based on quantitative genetic determination of the relative attack rates on the two hosts. The primary questions addressed are: (1) Do the different types of adaptive processes stabilize or destabilize the population dynamics? (2) Do the adaptive processes tend to equalize or to magnify differences in host densities? The models show that adaptive behavior and evolution frequently destabilize population dynamics and frequently increase the average difference between host densities. 相似文献
130.
Resource partitioning and interspecific competition in a tropical hermit crab community 总被引:1,自引:1,他引:0
Peter A. Abrams 《Oecologia》1980,46(3):365-379