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964.
Abigail C. Ross Leila M. Porter Michael L. Power Vince Sodaro 《Primates; journal of primatology》2010,51(4):315-325
Callimico goeldii gives birth to single offspring, whereas other callitrichids, including Callithrix jacchus, twin. This study compares maternal effort and infant development in C. goeldii and C. jacchus; it is the first study to look at nursing frequency. Infants were observed from birth for 7 weeks in two captive groups each
of C. goeldii and C. jacchus. C. goeldii mothers physiologically invested the same or less than C. jacchus mothers. C. goeldii mothers gained the same amount of weight during pregnancy in absolute terms as did the smaller C. jacchus. This results in a smaller gain in proportion to maternal weight but an equivalent proportional gain on a per fetus basis.
C. goeldii mothers nursed their infants less based on duration of nursing bouts compared with C. jacchus mothers. C. goeldii mothers transported their infants exclusively through the first 2 weeks of life, which is longer than C. jacchus mothers, who exclusively transported infants only during the first week of life. As maternal infant carriage declined, other
group members transported offspring in both species. C. goeldii infants engaged in independent locomotive sequences later in development and tasted solid foods less frequently than C. jacchus infants when compared at equivalent ages. A single, opportunistic milk sample obtained from a C. goeldii mother when her infant was 48 days old indicates that C. goeldii milk contains gross energy from crude protein within the range of variation observed in Callithrix milk. Despite the similarities in milk quality and prenatal effort in individual fetuses, C. goeldii infants gain weight faster from 0 to 18 months than do C. jacchus infants. A reduction in litter size allows C. goeldii mothers to spend more time carrying their infant and to delay weaning, thereby allowing accelerated infant and juvenile growth
rates compared with C. jacchus. 相似文献
965.
Thomas?H. Hraha Abigail?B. Bernard Linda?M. Nguyen Kristi?S. Anseth Richard?K.P. Benninger 《Biophysical journal》2014,106(1):299-309
Pancreatic islets of Langerhans regulate blood glucose homeostasis by the secretion of the hormone insulin. Like many neuroendocrine cells, the coupling between insulin-secreting β-cells in the islet is critical for the dynamics of hormone secretion. We have examined how this coupling architecture regulates the electrical dynamics that underlie insulin secretion by utilizing a microwell-based aggregation method to generate clusters of a β-cell line with defined sizes and dimensions. We measured the dynamics of free-calcium activity ([Ca2+]i) and insulin secretion and compared these measurements with a percolating network model. We observed that the coupling dimension was critical for regulating [Ca2+]i dynamics and insulin secretion. Three-dimensional coupling led to size-invariant suppression of [Ca2+]i at low glucose and robust synchronized [Ca2+]i oscillations at elevated glucose, whereas two-dimensional coupling showed poor suppression and less robust synchronization, with significant size-dependence. The dimension- and size-scaling of [Ca2+]i at high and low glucose could be accurately described with the percolating network model, using similar network connectivity. As such this could explain the fundamentally different behavior and size-scaling observed under each coupling dimension. This study highlights the dependence of proper β-cell function on the coupling architecture that will be important for developing therapeutic treatments for diabetes such as islet transplantation techniques. Furthermore, this will be vital to gain a better understanding of the general features by which cellular interactions regulate coupled multicellular systems. 相似文献
966.
Abigail Sewell 《Ethnic and racial studies》2018,41(8):1443-1446
The paradoxes, ironies, and juxtapositions of Black Lives Matter (BLM) have not been lost on those in, around, and outside of the movement: Using a philosophical and historical lens of black political thought informing the movement, Christopher J. Lebron gives voice to the tensions that arise because of the hypocrisy of devaluing black lives in a civil society that holds the equality of diverse people central to its foundation. The culmination of Lebron’s effort provides an opportunity to enhance current thinking on our contemporary social movements since he does a responsible job of handling the chorus of exigent voices that have contributed to a black radical tradition from which the Movement for Black Lives, the policy component of BLM, is branded. Lebron’s approach, however, would have benefitted from a more careful consideration of critical intersectionality, structuralist theories, and biological racism. 相似文献