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141.
Forrest A Huizinga JD Wang XY Liu LW Parsons M 《American journal of physiology. Gastrointestinal and liver physiology》2008,294(1):G315-G326
Diabetes affects many aspects of gastrointestinal motility, in part due to changes in interstitial cells of Cajal (ICC). The effect of diabetes on the colon, however, is not well characterized, and the aim of the present study was to investigate possible relationships between altered colonic motility as a consequence of streptozotocin-induced diabetes and injury to ICC. Physiological, immunohistochemical, and ultrastructural techniques were employed. The motor pattern of the rat colon was dominated by rhythmic high-amplitude, low-frequency contractions that were primarily myogenic in origin. These rhythmic contractions were induced by stretch associated with increased tension; the amplitude of the superimposed rhythmic contractions increased with increasing applied tension. In diabetic rats, the stretch-induced rhythmic contractile activity remained robust and of similar frequency but was significantly higher in amplitude compared with that in control rats. At 700 mg of applied tension, the force of contraction in circular colonic muscle strips of the diabetic rats was 370% of control values. This robust presence of low-frequency contractions is consistent with the unaffected pacemaker, the ICC associated with Auerbach's plexus, and the increased amplitude correlates with loss of and injury to ICC of the submuscular plexus and intramuscular ICC. Loss of inhibitory nitrergic nerves does not appear to be a factor based on unaltered nNOS immunoreactivity. 相似文献
142.
Prior flea beetle herbivory affects oviposition preference and larval performance of a potato beetle on their shared host plant 总被引:5,自引:0,他引:5
Abstract 1. The herbaceous plant Solanum carolinense (L.) (Solanaceae) is host to a number of specialist insects, including the leaf-feeding beetles Epitrix fuscula (Crotch) and Leptinotarsa juncta (Germar) (Coleoptera: Chrysomelidae). Potted individuals of S. carolinense were subjected to one of two treatments: exposure to herbivory by E. fuscula or exclusion of all herbivores. The effects of E. fuscula herbivory on larval performance and oviposition preference of L. juncta were investigated.
2. Although the masses of the L. juncta pupae did not differ between the two treatments, larvae feeding on damaged plants developed more slowly than those feeding on undamaged plants.
3. In both paired leaf choice trials and whole plant choice trials, larvae of L. juncta showed no preference for undamaged versus damaged hosts.
4. In a field transplant experiment, adult L. juncta females showed slight feeding preferences and strong oviposition preferences for undamaged plants versus plants that had been fed on by E. fuscula .
5. The results are discussed with reference to their implications for plant-mediated competition among herbivores and constraints on the evolution of plant resistance. 相似文献
2. Although the masses of the L. juncta pupae did not differ between the two treatments, larvae feeding on damaged plants developed more slowly than those feeding on undamaged plants.
3. In both paired leaf choice trials and whole plant choice trials, larvae of L. juncta showed no preference for undamaged versus damaged hosts.
4. In a field transplant experiment, adult L. juncta females showed slight feeding preferences and strong oviposition preferences for undamaged plants versus plants that had been fed on by E. fuscula .
5. The results are discussed with reference to their implications for plant-mediated competition among herbivores and constraints on the evolution of plant resistance. 相似文献
143.
144.
Kimberly M. Sheridan Abigail W. Konopasky Sophie Kirkwood Margaret A. Defeyter 《Philosophical transactions of the Royal Society of London. Series B, Biological sciences》2016,371(1690)
Research indicates that in experimental settings, young children of 3–7 years old are unlikely to devise a simple tool to solve a problem. This series of exploratory studies done in museums in the US and UK explores how environment and ownership of materials may improve children''s ability and inclination for (i) tool material selection and (ii) innovation. The first study takes place in a children''s museum, an environment where children can use tools and materials freely. We replicated a tool innovation task in this environment and found that while 3–4 year olds showed the predicted low levels of innovation rates, 4–7 year olds showed higher rates of innovation than the younger children and than reported in prior studies. The second study explores the effect of whether the experimental materials are owned by the experimenter or the child on tool selection and innovation. Results showed that 5–6 year olds and 6–7 year olds were more likely to select tool material they owned compared to tool material owned by the experimenter, although ownership had no effect on tool innovation. We argue that learning environments supporting tool exploration and invention and conveying ownership over materials may encourage successful tool innovation at earlier ages. 相似文献
145.
This study is focused on the possible use of Ceratocystis paradoxa MSR2 native biomass for Cr(VI) biosorption. The influence of experimental parameters such as initial pH, temperature, biomass dosage, initial Cr(VI) concentration and contact time were optimized using batch systems as well as response surface methodology (RSM). Maximum Cr(VI) removal of 68.72% was achieved, at an optimal condition of biomass dosage 2g L−1, initial Cr(VI) concentration of 62.5 mg L−1 and contact time of 60 min. The closeness of the experimental and the predicted values exhibit the success of RSM. The biosorption mechanism of MSR2 biosorbent was well described by Langmuir isotherm and a pseudo second order kinetic model, with a high regression coefficient. The thermodynamic study also revealed the spontaneity and exothermic nature of the process. The surface characterization using FT-IR analysis revealed the involvement of amine, carbonyl and carboxyl groups in the biosorption process. Additionally, desorption efficiency of 92% was found with 0.1 M HNO3. The Cr(VI) removal efficiency, increased with increase in metal ion concentration, biomass concentration, temperature but with a decrease in pH. The size of the MSR2 biosorbent material was found to be 80 μm using particle size analyzer. Atomic force microscopy (AFM) visualizes the distribution of Cr(VI) on the biosorbent binding sites with alterations in the MSR2 surface structure. The SEM-EDAX analysis was also used to evaluate the binding characteristics of MSR2 strain with Cr(VI) metals. The mechanism of Cr(VI) removal of MSR2 biomass has also been proposed. 相似文献
146.
Declines in brook charr (Salvelinus fontinalis) throughout its historic eastern United States of America (U.S.) range prompted the formation of the Eastern Brook Trout
[Charr] Joint Venture (Joint Venture) whose mandate is to restore these charr by working cooperatively at a range-wide, regional-scale.
Joint Venture habitat projects in the U.S. are initiated by local community-based organizations, assisted by fisheries management
institutions, and funded through the U.S. Fish and Wildlife Service. In order to assist with ranking these community-based
proposals for available funding, the Joint Venture designed a quantitative scoring method as a decision support tool that
addressed range-wide threats that were documented to limit brook charr production. These threats include habitat modification
(e.g., dams, urbanization, and agricultural landuse) and interactions with antagonistic non-native species [i.e., brown trout
(Salmo trutta) and rainbow trout (Oncorhynchus mykiss)]. This article evaluated the prioritization method used by comparing the quantitative rankings of the proposals with the
final reports for 12 completed projects using paired t tests for unequal sample sizes and variance. Two of the 12 comparisons revealed statistically significant differences (P < 0.05) between project proposals and final reports; namely, the scoring criteria for the proposals did not accurately reflect
the outcome of these projects in relation to brook charr management. Large inter-quartile ranges between reviewer scores were
common, indicating that the quantitative scoring method includes qualitative elements. In addition to the science-based criteria,
subjective value judgments by individual reviewers have factored into the Joint Venture’s decision making process. By evaluating
the decision support tool, this analysis aims to assist the Joint Venture in structuring its approach to conservation and
rehabilitation of brook charr populations in the eastern U.S. To better improve the Joint Venture’s ability to address brook
charr management on a regional level, we recommend that future proposal prioritization scoring criteria provide more explicit
guidance for accurate scoring, separate scoring methods for policy and assessment work, and a weighting factor for larger
than sub-watershed projects and for scoring criteria for which information is unknown. 相似文献
147.
Richard Spinney Lee Smith Marcella Ucci Abigail Fisher Marina Konstantatou Alexia Sawyer Jane Wardle Alexi Marmot 《PloS one》2015,10(5)
Little is known of the patterns of physical activity, standing and sitting by
office workers. However, insight into these behaviours is of growing interest,
notably in regard to public health priorities to reduce non-communicable disease
risk factors associated with high levels of sitting time and low levels of
physical activity. With the advent and increasing availability of indoor
tracking systems it is now becoming possible to build detailed pictures of the
usage of indoor spaces. This paper reports initial results of indoor tracking
used in conjunction with the ActivPAL activity monitoring device. In this paper
we give an overview of the usage of the tracking system and its installation and
illustrate some of the resultant data. We also provide preliminary results that
investigate the relationship between location, light physical activity and
sitting in a small sample of office workers (n=33) from two separate office
environments in order to demonstrate the relevance and explanatory power of the
technique. 相似文献
148.
Daniel H. Nussey Kathryn A. Watt Abigail Clark Jill G. Pilkington Josephine M. Pemberton Andrea L. Graham Tom N. McNeilly 《Proceedings. Biological sciences / The Royal Society》2014,281(1779)
Despite our rapidly advancing mechanistic understanding of vertebrate immunity under controlled laboratory conditions, the links between immunity, infection and fitness under natural conditions remain poorly understood. Antibodies are central to acquired immune responses, and antibody levels circulating in vivo reflect a composite of constitutive and induced functional variants of diverse specificities (e.g. binding antigens from prevalent parasites, self tissues or novel non-self sources). Here, we measured plasma concentrations of 11 different antibody types in adult females from an unmanaged population of Soay sheep on St Kilda. Correlations among antibody measures were generally positive but weak, and eight of the measures independently predicted body mass, strongyle parasite egg count or survival over the subsequent winter. These independent and, in some cases, antagonistic relationships point to important multivariate immunological heterogeneities affecting organismal health and fitness in natural systems. Notably, we identified a strong positive association between anti-nematode immunoglobulin (Ig) G antibodies in summer and subsequent over-winter survival, providing rare evidence for a fitness benefit of helminth-specific immunity under natural conditions. Our results highlight both the evolutionary and ecological importance and the complex nature of the immune phenotype in the wild. 相似文献
149.
150.