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21.
Summary Sequential cytogenetic studies of four patients with ataxia telangiectasia showed the progressive development of lymphocyte clones, each marked with a rearranged chromosome 14. Initial studies had shown random chromosomal breaks and rearrangements. Later studies in all patients showed nonrandom rearrangement of chromosome 14 with a breakpoint at 14q12 and with the distal segment translocated to either chromosome 14 or 7. The proportion of circulating lymphocytes carrying the marker tended to increase with time, accounting for the majority of the lymphocytes eventually in one case. The marked lymphocyte clones evolved further, as a result of loss of the small centric portions of the rearranged chromosome 14 (14pter14q12).Perhaps the abnormal clones in ataxia telangiectasia escape immunologic surveillance and flourish in an immunologically impaired environment. Subsequent to the loss of the centric portion of the rearranged chromosome 14, the cells may acquire additional capabilities that enhance malignant transformation. 相似文献
22.
A quantitative study of the effect of a microsporidan, Nosema locustae, as a control agent against grasshopper populations in Saskatchewan, Canada, revealed that 50% of the populations of Melanoplus sanguinipes, M. packardii, and Camnula pellucida were infected between 4 and 5 weeks (400 to 424 degree-days) after application of the pathogen. Maxima of 95–100% infection were evident between 9 and 12 weeks (600–700 degree-days) after application. The percentage reduction in surviving populations of M. sanguinipes, i.e., those that did not die from natural causes, reached about 20% by the 4th week (400 degree-days) after inoculation, about 50% by the 9th week (600 + degree-days), and a maximum of about 60% by the 12th week (700 degree-days). An exponential relationship was obtained between percentage reduction and percentage infection in all three species. However, a similar percentage infection resulted in different percentage reduction in the populations. Results also revealed that the rate of reduction in populations reached its peak by about 40–80 degree-days before the maximum rate of infection was attained for each species. Egg production in the two Melanoplus species in treated plots was significantly lower (P < 0.05) than in the control plot. 相似文献
23.
Effect of Polychlorinated Biphenyl Formulations on the Growth of Estuarine Bacteria 总被引:4,自引:4,他引:0 下载免费PDF全文
Polychlorinated biphenyl formulations inhibited the growth of certain estuarine bacteria. The sensitive strains, although exhibiting some similar physiological characteristics, contained both gram-positive and gram-negative bacteria. 相似文献
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25.
René Molinier Br.-Bl. C. Vanden Berghen Al. Borza N. Boscaiu T. Wraber 《Plant Ecology》1963,11(5-6):401-411
Sans résumé 相似文献
26.
Laura Noël-Romas Michelle Perner Refilwe Molatlhegi Christina Farr Zuend Amanda Mabhula Sarah Hoger Alana Lamont Kenzie Birse Alicia Berard Stuart McCorrister Garett Westmacott Al Leslie Vanessa Poliquin Renee Heffron Lyle R. McKinnon Adam D. Burgener 《PLoS pathogens》2020,16(12)
Alterations to the mucosal environment of the female genital tract, such as genital inflammation, have been associated with increased HIV acquisition in women. As the microbiome and hormonal contraceptives can affect vaginal mucosal immunity, we hypothesized these components may interact in the context of HIV susceptibility. Using previously published microbiome data from 685 women in the CAPRISA-004 trial, we compared relative risk of HIV acquisition in this cohort who were using injectable depot medroxyprogesterone acetate (DMPA), norethisterone enanthate (NET-EN), and combined oral contraceptives (COC). In women who were Lactobacillus-dominant, HIV acquisition was 3-fold higher in women using DMPA relative to women using NET-EN or COC (OR: 3.27; 95% CI: 1.24–11.24, P = 0.0305). This was not observed in non-Lactobacillus-dominant women (OR: 0.95, 95% CI: 0.44–2.15, P = 0.895) (interaction P = 0.0686). Higher serum MPA levels associated with increased molecular pathways of inflammation in the vaginal mucosal fluid of Lactobacillus-dominant women, but no differences were seen in non-Lactobacillus dominant women. This study provides data suggesting an interaction between the microbiome, hormonal contraceptives, and HIV susceptibility. 相似文献
27.
Shan Gao Michaela C. Strüder‐Kypke Khaled A. S. Al‐Rasheid Xiaofeng Lin Weibo Song 《Zoologica scripta》2010,39(3):305-313
Gao, S., Strüder‐Kypke, M.C., Al‐Rasheid, K.A.S., Lin, X. & Song, W. (2010). Molecular phylogeny of three ambiguous ciliate genera: Kentrophoros, Trachelolophos and Trachelotractus (Alveolata, Ciliophora).—Zoologica Scripta, 39, 305–313. Very few molecular studies on the phylogeny of the karyorelictean ciliates have been carried out because data of this highly ambiguous group are extremely scarce. In the present study, we sequenced the small subunit ribosomal RNA genes of three morphospecies representing two karyorelictean genera, Kentrophoros, Trachelolophos, and one haptorid, Trachelotractus, isolated from the South and East China Seas. The phylogenetic trees constructed using Bayesian inference, maximum likelihood, maximum parsimony and neighbor‐joining methods yielded essentially similar topologies. The class Karyorelictea is depicted as a monophyletic clade, closely related to the class Heterotrichea. The generic concept of the family Trachelocercidae is confirmed by the clustering of Trachelolophos and Tracheloraphis with high bootstrap support; nevertheless, the order Loxodida is paraphyletic. The transfer of the morphotype Trachelocerca entzi Kahl, 1927 to the class Litostomatea and into the new haptorid genus Trachelotractus, as suggested by previous researchers based on morphological studies, is consistently supported by our molecular analyses. In addition, the poorly known species Parduczia orbis occupies a well‐supported position basal to the Geleia clade, justifying the separation of these genera from one another. 相似文献
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29.
Ahlam Sayout Aicha Ouarhach Reda Rabie Ilham Dilagui Nabila Soraa Abderrahmane Romane 《化学与生物多样性》2020,17(1)
The genus Lavandula is known for its different uses in traditional medicine. This study is interested in the chemical composition of Lavandulapedunculata subsp.atlantica (Braun‐Blanq. ) Romo as well as evaluating its antibacterial potential against multi‐resistant strains. The analysis of Lavandulaatlantica essential oil (LAEO) allows the identification of 47 components representing 93.6 % of all identified. The main constituent of LAEO was camphor (50.4 %), followed by fenchone (14.1 %) and camphene (5.6 %). The antibacterial assays revealed that LAEO was active against all the studied bacteria. A preliminary study of the relationship between certain terpenoids and antibacterial activity was also carried out in order to note the compound(s) that are responsible for LAEO's antibacterial activity. This study showed that the activity of the essential oil may be due to the presence of certain minor compounds such as carvone, considering the presence of the synergistic effect between the essential oil. 相似文献
30.
Marko Jot Benjamin Lipovek Botjan Glaar Amran Al‐Ashouri Kristijan Brecl Gaper Mati
Artiom Magomedov Vytautas Getautis Marko Topi
Steve Albrecht 《Liver Transplantation》2020,10(25)
Perovskite solar cells (PSC) have shown that under laboratory conditions they can compete with established photovoltaic technologies. However, controlled laboratory measurements usually performed do not fully resemble operational conditions and field testing outdoors, with day‐night cycles, changing irradiance and temperature. In this contribution, the performance of PSCs in the rooftop field test, exposed to real weather conditions is evaluated. The 1 cm2 single‐junction devices, with an initial average power conversion efficiency of 18.5% are tracked outdoors in maximum power point over several weeks. In parallel, irradiance and air temperature are recorded, allowing us to correlate outside factors with generated power. To get more insight into outdoor device performance, a comprehensive set of laboratory measurements under different light intensities (10% to 120% of AM1.5) and temperatures is performed. From these results, a low power temperature coefficient of ?0.17% K?1 is extracted in the temperature range between 25 and 85 °C. By incorporating these temperature‐ and light‐dependent PV parameters into the energy yield model, it is possible to correctly predict the generated energy of the devices, thus validating the energy yield model. In addition, degradation of the tested devices can be tracked precisely from the difference between measured and modelled power. 相似文献