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761.
ALSuhaymi Naif Darwish Ahmed M. Khattab Abd El-Nasser 《Molecular biology reports》2021,48(5):4333-4340
Molecular Biology Reports - Diabetes is a metabolic disorder described as insufficient secretion of insulin in the pancreas or the inability of the existing insulin to function properly. It poses a... 相似文献
762.
Khalid M. El-Say Fathy I. Abd-Allah Ahmed E. Lila Abd El-Saboor A. Hassan Alaa Eldin A. Kassem 《Journal of liposome research》2016,26(1):57-68
The purpose of this study was to load diacerein (DCR) in niosomes by applying response surface methodology and incorporate these niosomes in gel base for topical delivery. Box–Behnken design was used to investigate the effect of charge-inducing agent (X1), surfactant HLB (X2) and sonication time (X3) on the vesicle size (Y1), entrapment efficiency (Y2) and cumulative drug released (Y3). DCR niosomal formulations were prepared by thin film hydration method. The optimized formula was incorporated in different gel bases. DCR niosomal gels were evaluated for homogeneity, rheological behavior; in vitro release and pharmacodynamic activity by carrageenan-induced hind paw edema method in the rat compared with DCR commercial gel. The results revealed that the mean vesicle sizes of the prepared niosomes ranged from 7.33 to 23.72?µm and the entrapment efficiency ranged from 9.52% to 58.43% with controlled release pattern over 8?h. DCR niosomal gels exhibited pseudoplastic flow with thixotropic behavior. The pharmacodynamic activity of DCR niosomal gel in 3% HPMC showed significant, 37.66%, maximum inhibition of edema size in comparison with 20.83% for the commercial gel (p?0.05). These results recommended the incorporation of DCR niosomes in 3% HPMC for topical application as a potent anti-inflammatory drug for the treatment of osteoarthritis. 相似文献
763.
H. M. Abd el-Samad 《Biologia Plantarum》1993,35(4):561-566
Salinity inhibited growth, and affected the contents of chlorophylls, carotenoids, saccharides, amino acids, proteins, DNA and RNA in broad bean plants. Foliar application of NaH2PO4 and NaNO3 greatly ameliorated the adverse effects of NaCI. This counteraction was associated with an increase in contents of saccharides, proteins, DNA and RNA. 相似文献
764.
Mohamed H. Abd El-Razek Ibrahim A. Saleh Sally Abdel-Halim Shaymaa M. Bata Ahmed F. Essa Taha A. Hussien Ahmed A. El-Beih Tarik A. Mohamed Mohamed-Elamir F. Hegazy 《化学与生物多样性》2023,20(8):e202201249
In the current study, both the essential oil composition and biological activity of Saussurea lappa and Ligusticum sinensis were investigated by means of microwave-assisted hydrodistillation (MAHD) and characterized by Gas chromatography/mass spectrometry (GC/MS), whereas the antimicrobial efficiency of MAHD essential oils was examined against four pathogens: Staphylococcus aureus, Escherichia coli, Aspergillus niger, and Candida albicans responsible for microbial infections. The goal was to spot synergy and a favorable method that gives essential oils to possibly use as alternatives to common antimicrobial agents for the treatment of bacterial infections using a microdilution assay. S. lappa's 21 compounds were characterized by MAHD extraction. Sesquiterpene lactones (39.7 % MAHD) represented the major components, followed by sesquiterpene dialdehyde (25.50 % MAHD), while L. sinensis's 14 compounds were identified by MAHD extraction. Tetrahydroisobenzofurans (72.94 % MAHD) was the predominant compound class. S. lappa essential oil collection showed the strongest antimicrobial activity with MIC values of 16 μg/ml against all pathogens tested, while L. sinensis showed strong antibacterial activity and moderate antifungal activity with MIC values of 32 μg/ml and 500 μg/ml, respectively. The principal components of both oils, (velleral, eremanthin and neocnidilide), were docked into the bacterial histidine kinase (HK) and the fungal heat shock protein 90 (Hsp90). 相似文献
765.
766.
Maswada Hanafey F. Abd El-Razek Usama A. El-Sheshtawy Abdel-Nasser A. Mazrou Yasser S. A. 《Journal of Plant Growth Regulation》2021,40(2):558-573
Journal of Plant Growth Regulation - Owing to water scarcity and environmental hazards of synthetic fertilizers, reducing water and chemical N fertilizers is very urgent for sustainable... 相似文献
767.
The effect of the topical application of the synthetic juvenile hormone JH-I on adult specimens of Musca domestica vicina Macq was studied. The adult stage responded to different JH-I concentrations in different ways. The gonotrophic cycle was shortened, the number of eggs decreased and the hatching rate was reduced. The adults of the next generation displayed a number of anomalies. The ovarian amino acid concentrations varied considerably according to the dose of JH-I and the stage of maturation of the relevant ovary. 相似文献
768.
769.
The removal of two eyestalks from Penaeus kerathurus (Leach) in the middle of the intermoult period was followed by very poor survival. Unilateral ablation was found to be sufficient for the induction of full maturation of the ovaries. 相似文献
770.
Summary The nature of the nitrogenous products formed in the cells and culture solutions of a nitrogen fixing strain of Nostoc commune was investigated. This organism was able to fix 5.4 mg nitrogen/100 mg dry algal cells. 13% of this cellular nitrogen was present in the soluble form. The assay of the different fractions of this soluble nitrogen was also made. Aspartic acid, glutamic acid and alanine were the only amino acids present in the free form. The extracellular nitrogen amounted to 30% of the total fixed nitrogen. The different fractions of this nitrogen were also assayed. Glutamic acid and aspartic acid were the only free amino acids in the culture solution. The importance of these two acids in the pathway of the fixation mechanism was discussed. 相似文献