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121.
C. Douglas Boyette Robert E. Hoagland Hamed K. Abbas 《Biocontrol Science and Technology》2007,17(2):171-178
An isolate of the fungus Myrothecium verrucaria was evaluated for its biocontrol potential against common purslane, horse purslane, spotted spurge, and prostrate spurge, all serious weed pests in commercial tomato fields in the southeastern US. In greenhouse and field tests, M. verrucaria was highly virulent against these weeds when applied as conidial sprays formulated in 0.2% Silwet L-77 surfactant, even in the absence of dew. In field test plots naturally infested with these weeds, seedlings in the two-to-three leaf growth stage treated with M. verrucaria at 2×107 conidia mL-1 in 0.2% Silwet, exhibited leaf and stem necrosis within 24 h following inoculation, with mortality occurring within 96 h. After 7 days, M. verrucaria had killed 90-95% of both purslane species and 85-95% of both spurge species. Tomatoes that were transplanted into plots treated with M. verrucaria remained healthy and vigorous throughout the growing season. Since M. verrucaria effectively controlled several common weeds under field conditions, this fungus appears to have potential as an effective bioherbicide for pre-plant weed control in production systems with transplanted tomato. 相似文献
122.
Efflux and tissue content of N-acetylaspartate (NAA) and amino acids were evaluated from cultured and acutely prepared hippocampal
slices in response to changes in osmolarity. The osmoregulator taurine, but not NAA, was lost from both types of slices after
moderate reductions in extracellular osmolarity (−60 mOsm) for 10–48 h. Hypoosmotic shock (−166 mOsm) for 5 min resulted in
unselective efflux of several amino acids from acutely prepared slices. Notably, the efflux of taurine, but not NAA, was prominent
also after the shock. Efflux of NAA was markedly enhanced by NMDA and high K+, in particular after the stimulation period. The high K+-mediated efflux was decreased by high extracellular osmolarity and a NMDA-receptor antagonist. The results indicate that
NAA efflux can be induced by a sudden non-physiological decrease in extracellular osmolarity but not by prolonged more moderate
changes in osmolarity. The mechanisms behind the efflux of NAA by high K+ are complex and may involve both swelling and activation of NMDA-receptors. 相似文献
123.
Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action 总被引:6,自引:0,他引:6
Lucas G Rymar VV Du J Mnie-Filali O Bisgaard C Manta S Lambas-Senas L Wiborg O Haddjeri N Piñeyro G Sadikot AF Debonnel G 《Neuron》2007,55(5):712-725
Current antidepressants are clinically effective only after several weeks of administration. Here, we show that serotonin(4) (5-HT(4)) agonists reduce immobility in the forced swimming test, displaying an antidepressant potential. Moreover, a 3 day regimen with such compounds modifies rat brain parameters considered to be key markers of antidepressant action, but that are observed only after 2-3 week treatments with classical molecules: desensitization of 5-HT(1A) autoreceptors, increased tonus on hippocampal postsynaptic 5-HT(1A) receptors, and enhanced phosphorylation of the CREB protein and neurogenesis in the hippocampus. In contrast, a 3 day treatment with the SSRI citalopram remains devoid of any effect on these parameters. Finally, a 3 day regimen with the 5-HT(4) agonist RS 67333 was sufficient to reduce both the hyperlocomotion induced by olfactory bulbectomy and the diminution of sucrose intake consecutive to a chronic mild stress. These findings point out 5-HT(4) receptor agonists as a putative class of antidepressants with a rapid onset of action. 相似文献
124.
Saeidnia S Gohari AR Hadjiakhoondi A Shafiee A 《Zeitschrift für Naturforschung. C, Journal of biosciences》2007,62(11-12):793-796
Trypanocidal activity was found in the volatile oil of dried Dracocephalum kotschyi. GC-MS analysis determined that the major constituents of the oil were geranial (35.8%), C10H14O (26.6%), limonene (15.8%) and 1,1-dimethoxy decane (14.5%). In order to isolate the unknown biologically active monoterpene, fractionation of the volatile oil was carried out by silica gel column chromatography. The structure of the oxygenated compound was confirmed to be limonene-10-al (C10H14O) by analysis of physical and spectroscopic data (1H NMR, 13C NMR, HMBC and HMQC). 相似文献
125.
Liang Chengcheng Raza Sayed Haidar Abbas Naqvi Muhammad Abuzar Raza Feng Yanrong Khan Rajwali Mohammedsaleh Zuhair M. Shater Abdullah F. Al-ahmadi Bassam M. Saleh Fayez M. Bilal Muhammad Ahsan Zan Linsen 《Biochemical genetics》2022,60(2):543-557
Biochemical Genetics - The Long non-coding RNA (lncRNA) expression profile data of ten samples including human Mesenchymal Stem Cell (MSC) adipogenic differentiation 0, 3, and 6 days from... 相似文献
126.
Farrokhzad Yusuf Babaei Alireza Yadollahi Abbas Kashkooli Arman Beyraghdar Mokhtassi-Bidgoli Ali Hesami Shahriar 《Plant Cell, Tissue and Organ Culture》2022,149(3):535-548
Plant Cell, Tissue and Organ Culture (PCTOC) - We tested the feasibility to promote growth and shoot proliferation of Phalaenopsis through different wavelengths of LED and fluorescent. Therefore,... 相似文献
127.
Mehmood Maryam Khan Muhammad Jadoon Khan Muhammad Jawad Akhtar Nadeem Mughal Fizza Shah Syed Tahir Abbas Hyder Muhammad Zeeshan Farrakh Sumaira Sadiq Irfan 《Molecular biology reports》2022,49(3):2059-2071
Molecular Biology Reports - Sesame is an ancient oilseed crop, known for its high oil content and quality. Its sensitivity to drought at early seedling stage is one of the limiting factors... 相似文献
128.
Gholipour Akram Shakerian Farshad Zahedmehr Ali Oveisee Maziar Maleki Majid Mowla Seyed Javad Malakootian Mahshid 《Molecular biology reports》2022,49(10):9267-9273
Molecular Biology Reports - Coronary artery disease (CAD), is the leading cause of mortality and morbidity worldwide. Tenascin-C (TNC) with high expression levels in inflammatory and cardiovascular... 相似文献
129.
Gholipour Parsa Komaki Alireza Parsa Hesam Ramezani Mahdi 《Neurochemical research》2022,47(7):2090-2108
Neurochemical Research - Hippocampal oxidative stress has a vital role in the pathophysiology of Alzheimer’s disease (AD)-associated behavioral deficits. Ecdysterone (Ecdy), a natural product... 相似文献
130.
Abbas Abou-Hamdan Pierre Ceccaldi Hugo Lebrette Oscar Gutiérrez-Sanz Pierre Richaud Laurent Cournac Bruno Guigliarelli Antonio L. De Lacey Christophe Léger Anne Volbeda Bénédicte Burlat Sébastien Dementin 《The Journal of biological chemistry》2015,290(13):8550-8558
The heterodimeric [NiFe] hydrogenase from Desulfovibrio fructosovorans catalyzes the reversible oxidation of H2 into protons and electrons. The catalytic intermediates have been attributed to forms of the active site (NiSI, NiR, and NiC) detected using spectroscopic methods under potentiometric but non-catalytic conditions. Here, we produced variants by replacing the conserved Thr-18 residue in the small subunit with Ser, Val, Gln, Gly, or Asp, and we analyzed the effects of these mutations on the kinetic (H2 oxidation, H2 production, and H/D exchange), spectroscopic (IR, EPR), and structural properties of the enzyme. The mutations disrupt the H-bond network in the crystals and have a strong effect on H2 oxidation and H2 production turnover rates. However, the absence of correlation between activity and rate of H/D exchange in the series of variants suggests that the alcoholic group of Thr-18 is not necessarily a proton relay. Instead, the correlation between H2 oxidation and production activity and the detection of the NiC species in reduced samples confirms that NiC is a catalytic intermediate and suggests that Thr-18 is important to stabilize the local protein structure of the active site ensuring fast NiSI-NiC-NiR interconversions during H2 oxidation/production. 相似文献