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排序方式: 共有230条查询结果,搜索用时 296 毫秒
71.
Nga Phung Amran Al‐Ashouri Simone Meloni Alessandro Mattoni Steve Albrecht Eva L. Unger Aboma Merdasa Antonio Abate 《Liver Transplantation》2020,10(20)
Halide perovskites are emerging as revolutionary materials for optoelectronics. Their ionic nature and the presence of mobile ionic defects within the crystal structure have a dramatic influence on the operation of thin‐film devices such as solar cells, light‐emitting diodes, and transistors. Thin films are often polycrystalline and it is still under debate how grain boundaries affect the migration of ions and corresponding ionic defects. Laser excitation during photoluminescence (PL) microscopy experiments leads to formation and subsequent migration of ionic defects, which affects the dynamics of charge carrier recombination. From the microscopic observation of lateral PL distribution, the change in the distribution of ionic defects over time can be inferred. Resolving the PL dynamics in time and space of single crystals and thin films with different grain sizes thus, provides crucial information about the influence of grain boundaries on the ionic defect movement. In conjunction with experimental observations, atomistic simulations show that defects are trapped at the grain boundaries, thus inhibiting their diffusion. Hence, with this study, a comprehensive picture highlighting a fundamental property of the material is provided while also setting a theoretical framework in which the interaction between grain boundaries and ionic defect migration can be understood. 相似文献
72.
Daniel Argaw Abate Mulugeta Mercè Herrero Nohelly Nombela Tsegemariam Teklu Teodros Tefera Zewdu Belew Jorge Alvar Caryn Bern 《PLoS neglected tropical diseases》2013,7(11)
Background
Visceral leishmaniasis is a lethal parasitic disease transmitted by phlebotomine sand flies. The largest focus of VL in Ethiopia is located in the lowland region bordering Sudan, where the epidemiology is complicated by the presence of thousands of seasonal agricultural workers who live under precarious conditions.Methodology/Principal Findings
We conducted two parallel case-control studies to identify factors associated with VL risk in residents and migrants. The studies were conducted from 2009 to 2011 and included 151 resident cases and 157 migrant cases, with 2 matched controls per case. In multivariable conditional regression models, sleeping under an acacia tree at night (odds ratios (OR) 5.2 [95% confidence interval 1.7–16.4] for residents and 4.7 [1.9–12.0] for migrants), indicators of poverty and lower educational status were associated with increased risk in both populations. Strong protective effects were observed for bed net use (OR 0.24 [0.12–0.48] for net use in the rainy season among residents, OR 0.20 [0.10–0.42] for any net use among migrants). For residents, living in a house with thatch walls conferred 5-fold and sleeping on the ground 3-fold increased risk. Among migrants, the risk associated with HIV status was borderline significant and sleeping near dogs was associated with 7-fold increased risk.Conclusions/Significance
Preventive strategies should focus on ways to ensure net usage, especially among migrant workers without fixed shelters. More research is needed to understand migration patterns of seasonal labourers and vector bionomics. 相似文献73.
Nitric oxide (NO) has been reported to act both as a destructive and a protective agent in the pathogenesis of the injuries
that occur during hypoxia/reoxygenation (H/R). It has been suggested that this dual role of NO depends directly on the isoform
of NO synthase (NOS) involved. In this work, we investigate the role that NO derived from endothelial NOS (eNOS) plays in
cardiac H/R-induced injury. Wistar rats were submitted to H/R (hypoxia for 30 min; reoxygenation of 0 h, 12 h and 5 days),
with or without prior treatment using the selective eNOS inhibitor l-NIO (20 mg/kg). Lipid peroxidation, apoptosis and protein nitration, as well as NO production (NOx), were analysed. The results
showed that l-NIO administration lowered NOx levels in all the experimental groups. However, no change was found in the lipid peroxidation
level, the percentage of apoptotic cells or nitrated protein expression, implying that eNOS-derived NO may not be involved
in the injuries occurring during H/R in the heart. We conclude that l-NIO would not be useful in alleviating the adverse effects of cardiac H/R. 相似文献
74.
Background and Aims
Nectar is a very complex mixture of substances. Some components (sugars and amino acids) are considered primary alimentary rewards for animals and have been investigated and characterized in numerous species for many years. In contrast, nectar proteins have been the subject of few studies and little is known of their function. Only very recently have detailed studies and characterization of nectar proteins been undertaken, and then for only a very few species. This current work represents a first step in the identification of a protein profile for the floral nectar of Cucurbita pepo. In this regard, the species studied is of particular interest in that it is monoecious with unisexual flowers and, consequently, it is possible that nectar proteins derived from male and female flowers may differ.Methods
Manually excised spots from two-dimensional (2-D) electrophoresis were subjected to in-gel protein digestion. The resulting peptides were sequenced using nanoscale LC–ESI/MS-MS (liquid chromatography–electrospray ionization/tandem mass spectrometry). An MS/MS ions search was carried out in Swiss-Prot and NCBInr databases using MASCOT software.Key Results
Two-dimensional electrophoresis revealed a total of 24 spots and a different protein profile for male and female flower nectar. Four main proteins recognized by 2-D electrophoresis most closely resemble β-d-xylosidases from Arabidopsis thaliana and have some homology to a β-d-xylosidase from Medicago varia. They were present in similar quantities in male and female flowers and had the same molecular weight, but with slightly different isoelectric points.Conclusions
A putative function for xylosidases in floral nectar of C. pepo is proposed, namely that they may be involved in degrading the oligosaccharides released by the nectary cell walls in response to hydrolytic enzymes produced by invading micro-organisms. Several types of oligosaccharides have been reported to increase the pathogenic potential of micro-organisms. Thus, it is possible that such a mechanism may reduce the virulence of pathogens present in nectar. 相似文献75.
Marta A. Polti Mariana C. AtjiánMaría J. Amoroso Carlos M. Abate 《International biodeterioration & biodegradation》2011,65(8):1175-1181
The aim of this work was to evaluate a strategy to reduce the bioavailable chromium fraction in soil, using a Cr(VI) resistant microorganism, Streptomyces sp. MC1, under non sterile conditions, with maize plants as bioindicator and/or bioremediator.Soil samples were contaminated with 100, 200 and 400 mg kg−1 of Cr(VI) or Cr(III). Bioavailable chromium (35%) was only detected in samples with Cr(VI). Soil samples with Cr(VI) 200 mg kg−1 were inoculated with Streptomyces sp. MC1, and bioavailable chromium decreased up to 73%.Zea mays seedlings were planted in soil samples contaminated with chromium. Plantlets accumulated chromium mainly as Cr(III), and biomass decreased up to 88%. Streptomyces sp. MC1 was inoculated in soil samples contaminated with 200 mg kg−1 of Cr(VI) and Z.mays seedlings were planted.Streptomyces sp. MC1 caused Z.mays biomass increase (57%), chromium accumulation and bioavailable chromium decreased up to 46% and 96%, respectively.This work constitutes the first contribution of cooperative action between actinobacteria and Z.mays in the bioremediation of Cr(VI) contaminated soil. The large removal capacity of bioavailable chromium by Streptomyces sp. MC1 and Z.mays infers that they could be successfully applied together in bioremediation of soils contaminated with Cr(VI). 相似文献
76.
QTL associated with Fusarium head blight resistance in the soft red winter wheat Ernie 总被引:2,自引:0,他引:2
Liu S Abate ZA Lu H Musket T Davis GL McKendry AL 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》2007,115(3):417-427
Fusarium head blight (FHB), mainly caused by Fusarium graminearum Schwabe [telomorph: Gibberella zeae Schw. (Petch)], is an increasingly important disease of wheat (Triticum aestivum L.). Host-plant resistance provides the best hope for reducing economic losses associated with FHB, but new sources of resistance
are limited. The moderately resistant winter wheat cultivar, Ernie, may provide a source of resistance that differs from Sumai
3 but these genes have not been mapped. Also hindering resistance breeding may be associations of resistance with agronomic
traits such as late maturity that may be undesirable in some production environments. This research was conducted to identify
QTL associated with type II FHB resistance (FHB severity, FHBS), and to determine if they are associated with days to anthesis
(DTA), number of spikelets (NOS), and the presence/absence of awns. Two hundred and forty-three F8 recombinant inbred lines from a cross between the resistant cultivar, Ernie and susceptible parent, MO 94-317 were phenotyped
for type II FHB resistance using point inoculation in the greenhouse during 2002 and 2003. Genetic linkage maps were constructed
using 94 simple sequence repeat (SSR) and 146 amplified fragment length polymorphic (AFLP) markers. Over years four QTL regions
on chromosomes 2B, 3B, 4BL and 5A were consistently associated with FHB resistance. These QTL explained 43.3% of the phenotypic
variation in FHBS. Major QTL conditioning DTA and NOS were identified on chromosome 2D. Neither the QTL associated with DTA
and NOS nor the presence/absence of awns were associated with FHB resistance in Ernie. Our results suggest that the FHB resistance
in Ernie appears to differ from that in Sumai 3, thus pyramiding the QTL in Ernie with those from Sumai 3 could result in
enhanced levels of FHB resistance in wheat. 相似文献
77.
Rossana Martini Simonetta Cirilli Céline Saurer Benedetto Abate Gaetano Ferruzza Giovanna Lo Cicero 《Facies》2007,53(3):389-400
The aims of this study are to reconstruct the geological setting of the Punta Bassano series (Marettimo Island, Egadi Archipelago,
western Sicily) and its palaeogeographic evolution. The reference section for the Upper Triassic of Marettimo shows an alternation
of marl and limestone beds together with brecciated levels. The limestones are both homogeneous mudstones with evaporite pseudomorphs
and laminated with fenestrae. Foraminiferal, palynomorph, and ostracod associations constrain the Punta Bassano sequence to
the Carnian-Rhaetian interval. The Punta Bassano succession represents a shallow inner ramp, ranging from open-marine environment
with good water circulation to lagoonal and peritidal protected environments. Freshwater input from rivers or groundwater
on the carbonate ramp is indicated by the ostracod microfauna. The comparison of facies and microfauna with those from other
sequences of the Mediterranean Upper Triassic (Pyrenees, Corsica, Sardinia, and Tunisia) allows us to confine the Punta Bassano
sedimentation to the northern margin of the Tethys, between the Corsican and the Pyrenean depositional setting. These new
results indicate that Marettimo Island, which is considered a single structural element being formed by four tectonic units,
is a piece of the southern margin of the European Plate, displaced over a longer distance to become part of the other Egadi
Islands, when the Corso-Sarde block made its rotation and successive collision with the North African Margin. 相似文献
78.
79.
80.
Massimo Nepi Chiara Soligo Daniele Nocentini Mariangela Abate Massimo Guarnieri Giampiero Cai Luca Bini Michele Puglia Laura Bianchi Ettore Pacini 《Flora》2012
Nectar is considered a primary alimentary reward for a large variety of pollinators. Recent studies demonstrated that nectar may have other functions in addition to attracting pollinators. Mainly other two functions have been recognized: defense against microbial invasion and post-secretion modification of sugar profile. The floral nectar of Cucurbita pepo L. has been analyzed to confirm the presence of defense proteins, namely xylosidases that were identified by means of a proteomic approach in a previous study. An enzyme assay was also performed that revealed low invertase activity for which the optimal pH was determined. This invertase activity is not able to modify the sugar profile significantly during the short period of anthesis (6 h). The amino acids complement of the nectar of both sexes was also determined. Sixteen of the 20 protein amino acids have been detected. Proline comprises more than 30% of total amino acid content in male and female flowers. Three non-protein amino acids (taurine, β-alanine, and GABA) represent almost one third of the total amino acid content, and of these, GABA is the most abundant (16%). Several biological activities were attributed to these amino acids and further studies are needed to assess their presumed involvement in managing the foraging behavior of insects. More recent studies, including our own, demonstrate that the various functions of nectar are much more complex than previously thought. 相似文献