全文获取类型
收费全文 | 405篇 |
免费 | 25篇 |
国内免费 | 9篇 |
出版年
2023年 | 3篇 |
2022年 | 3篇 |
2021年 | 3篇 |
2020年 | 3篇 |
2018年 | 4篇 |
2017年 | 7篇 |
2015年 | 9篇 |
2014年 | 7篇 |
2013年 | 11篇 |
2012年 | 11篇 |
2011年 | 10篇 |
2010年 | 12篇 |
2009年 | 17篇 |
2008年 | 19篇 |
2007年 | 12篇 |
2006年 | 13篇 |
2005年 | 4篇 |
2004年 | 9篇 |
2003年 | 6篇 |
2001年 | 8篇 |
2000年 | 3篇 |
1999年 | 10篇 |
1998年 | 6篇 |
1997年 | 7篇 |
1996年 | 13篇 |
1995年 | 3篇 |
1994年 | 6篇 |
1992年 | 2篇 |
1991年 | 2篇 |
1989年 | 2篇 |
1983年 | 4篇 |
1980年 | 3篇 |
1979年 | 2篇 |
1978年 | 6篇 |
1976年 | 2篇 |
1974年 | 3篇 |
1972年 | 2篇 |
1959年 | 7篇 |
1958年 | 23篇 |
1957年 | 26篇 |
1956年 | 26篇 |
1955年 | 22篇 |
1954年 | 22篇 |
1953年 | 13篇 |
1952年 | 13篇 |
1951年 | 10篇 |
1950年 | 9篇 |
1949年 | 2篇 |
1948年 | 2篇 |
1912年 | 2篇 |
排序方式: 共有439条查询结果,搜索用时 31 毫秒
21.
22.
23.
24.
The climate of the native tropical forest habitats of Hylocereus undatus, a hemiepiphytic cactus cultivated in 20 countries for its fruit, can help explain the response of its net CO2 uptake to environmental factors. Under wet conditions, about 85% of the total daily net CO2 uptake occurs at night via Crassulacean acid metabolism, leading to a high water‐use efficiency. Total daily net CO2 uptake is reduced 57% by only 10 days of drought, possibly involving stomatal closure induced by abscisic acid produced in the roots, which typically occupy a small substrate volume. Total daily net CO2 uptake for H. undatus is maximal at day/night air temperatures of 30/20°C, optimal temperatures that are higher than those for desert cacti but representative of ambient temperatures in the tropics; its total daily net CO2 uptake becomes zero at day/night air temperatures of 42/32°C. Stem damage occurs at 45°C for H. undatus, whose photosynthetic cells show little acclimation to high temperatures compared with other cacti and are also sensitive to low temperatures, ‐1.5°C killing half of these cells. Consistent with its shaded habitat, total daily net CO2 uptake is appreciable at a total daily PPF of only 2 mol m2 day' and is maximal at 20 mol m?2 day?1, above which photoinhibition reduces net CO2 uptake. Net CO2 uptake ability, which is highly correlated with stem nitrogen and chlorophyll contents, changes only gradually (halftimes of 2–3 months) as the concentration of applied N is changed. Doubling the atmospheric CO2 concentration raises the total daily net CO2 uptake of H. undatus by 34% under optimal conditions and by even larger percentages under adverse environmental conditions. 相似文献
25.
Hormonal imprinting takes place at the first encounter of the hormone and receptor, and results in a changed binding capacity and reaction of the cell and its progeny generations. The imprinting effect of three amino acids and their oligopeptides is studied using fluorescent-labelled peptides. Glycine and lysine could provoke positive imprinting (increased binding in the progeny generations) for their own peptides, but alanine could not. Mostly positive imprinting was provoked by glycine and lysine peptides for their own peptides of different chain length. The optimal chain length provoking self-imprinting was four for glycine, two for lysine and three for alanine. Except in this case, alanine was neutral or provoked mostly negative imprinting. After reaching the optimal chain length, there is a decline in binding. Evolutionary conclusions are discussed. 相似文献
26.
D.W. Brammer C.M. O'Rourke LA Heath C.E. Chrlsp G.K. Peter G.L. Hofing 《Journal of medical primatology》1995,24(4):231-235
Abstract: This report documents asymptomatic infections of Mycobacterium kansasii in four of five tuberculin positive squirrel monkeys (Saimiri sciureus sciureus). The mycobacterial DNA amplified by polymerase chain reaction (PCR) from a bronchial lymph node had no affinity for the species specific probes of M. tuberculosis, M. avium, and M. intracellular, thus allowing the presumptive diagnosis of an atypical mycobacterial infection. Infection by Mycobacterium kansasii was confirmed by culture of bronchial lymph nodes from three monkeys. The source of the infection was never identified. 相似文献
27.
The effects of an auxin herbicide, 2,4-D, at a concentration of 0.01 mM, on the K+ uptake and efflux of excised roots of wheat (Triticum aestivum L. cv. Rannaya) were investigated at different pH values. The K+ movement was monitored with a K+ (86Rb) tracer. In parallel experiments the ATPase activities of microsomal fractions were determined by the inorganic phosphate liberation method. 2,4-D inhibited the K+ uptake especially at low pH, irrespective of whether Ca2+ was present or not. No marked changes were observed in the K+ efflux properties at pH values above 4. The inhibitory effect on K+ uptake exhibited a correlation with the hydrocarbon solubility of the herbicide, but not with the 2,4-D-induced decrease of the ATPase activity. It is suggested that 2,4-D exerts a non-specific effect on the lipid-protein interactions, giving rise to a generalized alteration of the transport barrier properties of the plasma membrane even at as low a concentration as 0.01 mM. 相似文献
28.
29.
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes 总被引:9,自引:0,他引:9 下载免费PDF全文
Zhou XP Woodford-Richens K Lehtonen R Kurose K Aldred M Hampel H Launonen V Virta S Pilarski R Salovaara R Bodmer WF Conrad BA Dunlop M Hodgson SV Iwama T Järvinen H Kellokumpu I Kim JC Leggett B Markie D Mecklin JP Neale K Phillips R Piris J Rozen P Houlston RS Aaltonen LA Tomlinson IP Eng C 《American journal of human genetics》2001,69(4):704-711
Juvenile polyposis syndrome (JPS) is an inherited hamartomatous-polyposis syndrome with a risk for colon cancer. JPS is a clinical diagnosis by exclusion, and, before susceptibility genes were identified, JPS could easily be confused with other inherited hamartoma syndromes, such as Bannayan-Riley-Ruvalcaba syndrome (BRRS) and Cowden syndrome (CS). Germline mutations of MADH4 (SMAD4) have been described in a variable number of probands with JPS. A series of familial and isolated European probands without MADH4 mutations were analyzed for germline mutations in BMPR1A, a member of the transforming growth-factor beta-receptor superfamily, upstream from the SMAD pathway. Overall, 10 (38%) probands were found to have germline BMPR1A mutations, 8 of which resulted in truncated receptors and 2 of which resulted in missense alterations (C124R and C376Y). Almost all available component tumors from mutation-positive cases showed loss of heterozygosity (LOH) in the BMPR1A region, whereas those from mutation-negative cases did not. One proband with CS/CS-like phenotype was also found to have a germline BMPR1A missense mutation (A338D). Thus, germline BMPR1A mutations cause a significant proportion of cases of JPS and might define a small subset of cases of CS/BRRS with specific colonic phenotype. 相似文献
30.
H. Aaltonen J. Aalto P. Kolari M. Pihlatie J. Pumpanen M. Kulmala E. Nikinmaa T. Vesala J. Bäck 《Plant and Soil》2013,369(1-2):241-256