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31.
Neodiaptomus schmackeri and related species are redescribed. The synonymy of this species with N. strigilipes and N. handeli is discussed. 相似文献
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Plasmonics - Silver nano-hexagons have been prepared through the reduction of silver ions by ethylene glycol with poly (vinyl pyrrolidone) (PVP) as a capping agent or stabilizing agent. The... 相似文献
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Lucjan Śawia̧tek Daniel Lehmann Ratan K. Chaudhuri Otto Sticher 《Phytochemistry》1981,20(8):2023-2024
The 13C NMR and 360 MHz 1H NMR signals of melittoside and its acetate have been assigned. 相似文献
36.
Gary E. Gibson Anatoly Starkov John P. Blass Rajiv R. Ratan M. Flint Beal 《生物化学与生物物理学报:疾病的分子基础》2010,1802(1):122-134
37.
Meyyappan Arumugam Anindita Mitra Parasuraman Jaisankar Shreya Dasgupta Tuhinadri Sen Ratan Gachhui Ujjal Kumar Mukhopadhyay Joydeep Mukherjee 《Applied microbiology and biotechnology》2010,86(1):109-117
A marine actinobacterium isolated from the Bay of Bengal, India and previously found to be producing an antimicrobial and
cytotoxic terpenoid was further investigated for antimicrobial metabolites. The bacterium was preliminarily identified as
a new species of the genus Streptomyces (strain MS1/7). The cell-free culture broth was extracted with n-butanol and purified using silica gel column chromatography and high-performance liquid chromatography. Molecular characterization
was done using ESI mass, IR and 1H and 13C NMR spectrometry. 2-Allyloxyphenol (MW 150; C9H10O2), a synthetic drug and chemical intermediate, was obtained as a natural product for the first time. Serendipitous natural
occurrence provided new insights into the synthetic molecule. 2-Allyloxyphenol was found to be inhibitory to 21 bacteria and
three fungi in the minimum range 0.2–1.75 mg mL−1 determined by agar dilution method. 2-Allyoxyphenol possesses strong antioxidant property (IC50 22 μg mL−1, measured by 1, 1-diphenyl-2-picryl hydrazyl scavenging activity). Hydroxyl and allyloxy groups in 2-allyloxyphenol were
responsible for antimicrobial and antioxidant activities. 2-Allyloxyphenol has marked resemblance to smoky aroma and is two
to three times more active as an antimicrobial than some commercial smoke-flavour compounds. Absence of hemolytic toxicity,
potential carcinogenicity, cytotoxicity and reports of toxic reactions in literature suggest possible application of 2-allyloxyphenol
as a food preservative and an oral disinfectant. 相似文献
38.
Lin KI Pasinelli P Brown RH Hardwick JM Ratan RR 《The Journal of biological chemistry》1999,274(19):13650-13655
Infection of many cultured cell types with Sindbis virus (SV), an alphavirus, triggers apoptosis through a commonly utilized caspase activation pathway. However, the upstream signals by which SV activates downstream apoptotic effectors, including caspases, remain unclear. Here we report that in AT-3 prostate carcinoma cells, SV infection decreases superoxide (O-2) levels within minutes of infection as monitored by an aconitase activity assay. This SV-induced decrease in O-2 levels appears to activate or modulate cell death, as a recombinant SV expressing the O-2 scavenging enzyme, copper/zinc superoxide dismutase (SOD), potentiates SV-induced apoptosis. A recombinant SV expressing a mutant form of SOD, which has reduced SOD activity, has no effect. The potentiation of SV-induced apoptosis by wild type SOD is because of its ability to scavenge intracellular O-2 rather than its ability to promote the generation of hydrogen peroxide. Pyruvate, a peroxide scavenger, does not affect the ability of wild type SOD to potentiate cell death; and increasing the intracellular catalase activity via a recombinant SV vector has no effect on SV-induced apoptosis. Moreover, increasing intracellular O-2 by treatment of 3T3 cells with paraquat protects them from SV-induced death. Altogether, our results suggest that SV may activate apoptosis by reducing intracellular superoxide levels and define a novel redox signaling pathway by which viruses can trigger cell death. 相似文献
39.
Fugu immunoglobulin D: a highly unusual gene with unprecedented duplications in its constant region 总被引:4,自引:1,他引:3
We have isolated and characterized the cDNA that encodes IgD of fugu (Takifugu rubripes). Though the splicing of 1 with the 1 domain was similar to those reported for teleost IgDs, highly unusual and unprecedented domain duplications were found in the constant region of the fugu IgD. The structure of the fugu IgD is like VDJ-1-(1-2-3-4-5-6)2-7-m1-m2. Genomic sequence analysis of the fugu IgD gene supported the results of cDNA sequencing that the first six domains in the constant region are duplicated. Such a novel duplication pattern has not been reported in any other vertebrates. However, IgD secretory domains could not be identified in this study. The deduced amino acid sequence of the fugu IgD constant region showed high identity (35–55%) to the sequences of previously reported teleost IgDs. Gene expression analyses based on RT-PCR demonstrated that the IgD gene is preferentially expressed in presumptive lymphoid tissues; moreover, in situ hybridization showed that IgD-positive cells are distributed throughout the spleen and head kidney. The expression pattern is similar to that of IgM, corroborating the hypothesis that IgD plays an important role in the humoral immune system of this species.The nucleotide sequence data reported in this paper will appear in the DDBJ/EMBL/GenBank nucleotide sequence databases with the accession numbers AB159481 and AB159482. 相似文献