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排序方式: 共有372条查询结果,搜索用时 46 毫秒
51.
Gülhan Vardar-Ünlü Sibel Silici Mehmet Ünlü 《World journal of microbiology & biotechnology》2008,24(7):1011-1017
The antibacterial activity of propolis has been widely investigated. Since reports dealing with antimicrobial activity of
the origin of propolis are not available, this study was carried out aiming to analyse the in vitro antimicrobial activity
of the methanol extracts of poplar type propolis and Populus (Populus nigra, P. alba, P. tremuloides) buds as its sources against standard strains of a panel of microorganisms by determining the minimum inhibitory concentration
(MIC) and minimum bactericidal concentration (MBC). The concentrations of the “poplar” phenolics were relatively high (4.5%)
and some compounds typical for P. nigra such as pinobanksin and 4,3 acetyloxycaffeate were found in the propolis sample by GC-MS. The poplar type propolis and Populus
bud exudates were found to inhibit most clinically important microorganisms in a wide spectrum including pathogenic yeasts
but not Gram-negative bacteria. 相似文献
52.
Molecular Characterization of Two Lactate Dehydrogenase Genes with a Novel Structural Organization on the Genome of Lactobacillus sp. Strain MONT4
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Two lactate dehydrogenase (ldh) genes from Lactobacillus sp. strain MONT4 were cloned by complementation in Escherichia coli DC1368 (ldh pfl) and were sequenced. The sequence analysis revealed a novel genomic organization of the ldh genes. Subcloning of the individual ldh genes and their Northern blot analyses indicated that the genes are monocistronic. 相似文献
53.
Effect of Strontium Ranelate on Hydrogen Peroxide-Induced Apoptosis of CRL-11372 Cells 总被引:2,自引:0,他引:2
Senkoylu A Yilmaz A Ergun MA Ilhan MN Simsek A Altun N Bolukbasi S Menevse S 《Biochemical genetics》2008,46(3-4):197-205
In vitro and in vivo studies have proven strontium to be an osteoinductive trace element. The effect of strontium ranelate
(SR) on H2O2-induced apoptosis of CRL-11372 cells and optimization of its anti-apoptotic dose were the aims of this study. After 1 h of
pretreatment with SR 1 μM, 50 μM, 100 μM, 500 μM, and 1,000 μM concentrations, CRL-11372 osteoblasts were exposed to 100 μM H2O2 for periods of 6–12 h. The same experiments were repeated without H2O2. The apoptotic index and viability of cells were assessed quantitatively with a fluorescent dye and qualitatively with agarose
gel electrophoresis. Concentrations of 1–100 μM of SR with a 6-h treatment and only 1 μM concentration with a 12-h treatment
inhibited the apoptotic effect of H2O2 on cultured osteoblasts significantly (P < 0.05). SR was shown to inhibit H2O2-induced apoptosis of CRL-11372 cells in a dose-dependent manner. 相似文献
54.
Extracellular proteases produced by Scytalidium thermophilum, grown on microcrystalline cellulose, were most active at pH 6.5–8 and 37–45 °C when incubated for 60 min. Highest protease activity was at day 3 where endoglucanase activity was low. Protease activity measurements with and without the protease inhibitors, p-chloromercuribenzoate, PMSF, antipain, E-64, EDTA and pepstatin A, suggest production of thiol-containing serine protease and serine proteases. Endoglucanase and Avicel-adsorbable endoglucanase activity in culture medium was not significantly affected by protease inhibitors. 相似文献
55.
K Srikanth T Murugesan Ch Anil Kumar V Suba A K Das S Sinha G Arunachalam L Manikandan 《Phytomedicine》2002,9(1):75-77
The effect of methanol extract of whole plants of Trichodesma indicum R. Br. has been investigated on sulphur dioxide (SO2) induced cough reflex in Swiss albino mice. The extract has demonstrated significant (p < 0.001) inhibition in frequency of cough in all the tested doses when compared with untreated control group. The effect persisted up to 90 min of its oral administration and also comparable to that of the effect exhibited by the standard drug (Codeine phosphate). This study confirmed the traditional use of this plant in the treatment of cough. Determination of underlying mechanism of beneficial effect is major topic requiring further comprehensive investigation. 相似文献
56.
Altinoz Meric A. Topcu Gulacti Hacimuftuoglu Ahmet Ozpinar Alp Ozpinar Aysel Hacker Emily Elmaci İlhan 《Neurochemical research》2019,44(8):1796-1806
Neurochemical Research - Noscapine is a phthalide isoquinoline alkaloid that easily traverses the blood brain barrier and has been used for years as an antitussive agent with high safety. Despite... 相似文献
57.
Didem Şöhretoğlu Merve Yüzbaşıoğlu Baran Randolph Arroo Ayşe Kuruüzüm-Uz 《Phytochemistry Reviews》2018,17(5):973-1005
Polydatin (PLD), the 3-O-β-glucopyranoside of the well-known stilbenoid compound resveratrol, is a major compound of Fallopia japonica (Houtt.) R. Decr. (Japanese knotweed), which is widely used in traditional Chinese medicine to treat infection, inflammatory diseases and circulatory problems. It has shown a wide range of biological activities including anti-inflammatory, anti-oxidant, anti-cancer, neuroprotective, hepatoprotective, nephroprotective and immunostimulatory effects. Although resveratrol has similar beneficial effects, its low bioavailability has remained a problem. Glycosylation increases solubility of resveratrol in an aqueous environment, thus improving its bioavailability. This has led to a growing interest in PLD. Promising results obtained from bioactivity studies have boosted an intense research on this compound. The aim of this review is to give a comprehensive overview of the botanical sources, pharmacology, biosynthesis, biotechnological production, and bioactivities of PLD, and to discuss clinical studies on this compound. 相似文献
58.
First record of red cornetfish Fistularia petimba (Syngnathiformes:Fistulariidae) from Antalya and İskenderun Bays along Turkish Coasts of the Mediterranean Sea
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A. Ünlüoğlu S. Akalın İ. Dal E. M. Tıraşın C. M. Aydın 《Zeitschrift fur angewandte Ichthyologie》2018,34(4):977-980
Here, we report the first occurrence of red cornetfish Fistularia petimba in the north‐eastern Mediterranean Sea. Altogether four specimens were captured; first two in Antalya Bay on 28 October 2016 and 26 November 2016, and the remaining two in ?skenderun Bay on 21 May 2017 during the bottom trawl surveys along the Mediterranean coast of Turkey. All specimens were young and more or less uniform in size (383, 335, 419 and 453 mm standard length). The possibility that F. petimba could become a new potential invader in the Mediterranean as its congeneric F. commersonii is cautioned against. 相似文献
59.
Muhammet Serhat Özaslan Yeliz Demir Hatice Esra Aslan Şükrü Beydemir Ömer İrfan Küfrevioğlu 《Journal of biochemical and molecular toxicology》2018,32(5)
Glutathione S‐transferases (GSTs) are the superfamily of multifunctional detoxification isoenzymes and play an important role in cellular signaling. In the present study, potential inhibition effects of chalcones were tested against human GST. For this purpose, GST was purified from human erythrocytes with 5.381 EU?mg?1 specific activity and 51.95% yield using a GSH–agarose affinity chromatographic method. The effects of chalcones on in vitro GST activity were tested at various concentrations. Ki constants of chalcones were found in the range of 7.76–41.93 μM. According to the results, 4‐fluorochalcone showed a better inhibitory effect compared with the other compounds. The inhibition mechanisms of 2'‐hydroxy‐4‐methoxychalcone and 4‐methoxychalcone were noncompetitive, whereas the inhibition mechanisms of 4'‐ hydroxychalcone, 4‐ fluorochalcone, and 4,4'‐ diflurochalcone were competitive. 相似文献
60.
Pomatoschistus anatoliae sp. n. is described from estuary of Göksu River on the Mediterranean coast of the Anatolia. It is distinguished from its congeners by the suborbital papilla pattern, meristic, and ecological features. DNA barcoding based on COI sequences revealed that there is a high nucleotide sequence divergence to the nearest neighbour. Kimura’s two parameter distances between P. anatoliae sp. n. and other species of Pomatoschistus and Knipowitchia have found to be at least 5.1%.
http://www.zoobank.org/urn:lsid:zoobank.org:pub:4592CF50-07B5-4C25-892F-5D009057675B 相似文献