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Today, the workflows that are involved in industrial assembly and production activities are becoming increasingly complex. To efficiently and safely perform these workflows is demanding on the workers, in particular when it comes to infrequent or repetitive tasks. This burden on the workers can be eased by introducing smart assistance systems. This article presents a scalable concept and an integrated system demonstrator designed for this purpose. The basic idea is to learn workflows from observing multiple expert operators and then transfer the learnt workflow models to novice users. Being entirely learning-based, the proposed system can be applied to various tasks and domains. The above idea has been realized in a prototype, which combines components pushing the state of the art of hardware and software designed with interoperability in mind. The emphasis of this article is on the algorithms developed for the prototype: 1) fusion of inertial and visual sensor information from an on-body sensor network (BSN) to robustly track the user’s pose in magnetically polluted environments; 2) learning-based computer vision algorithms to map the workspace, localize the sensor with respect to the workspace and capture objects, even as they are carried; 3) domain-independent and robust workflow recovery and monitoring algorithms based on spatiotemporal pairwise relations deduced from object and user movement with respect to the scene; and 4) context-sensitive augmented reality (AR) user feedback using a head-mounted display (HMD). A distinguishing key feature of the developed algorithms is that they all operate solely on data from the on-body sensor network and that no external instrumentation is needed. The feasibility of the chosen approach for the complete action-perception-feedback loop is demonstrated on three increasingly complex datasets representing manual industrial tasks. These limited size datasets indicate and highlight the potential of the chosen technology as a combined entity as well as point out limitations of the system.  相似文献   
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The influence of an active Trypanosoma (Schizotrypanum) cruzi infection in mice and the subsequent immune response to an administered unrelated, erythrocyte antigen was studied. When mice were infected with blood forms of the parasite, a depression of the humoral immune response to injected burro erythrocytes (BE), was observed. The suppression became evident at a time when the magnitude of parasitemia and tissue forms was increasing in the sensitized and infected mice. The immunosuppressive effect induced by the infection to BE was demonstrated by a diminished direct (19S) and indirect (7S) antibody-forming cell response. Additionally, a significant increase in phagocytic activity was observed in T. cruzi-infected mice using colloidal carbon uptake experiments. Probable mechanisms of suppression are discussed and related to accepted lymphocyte activities.  相似文献   
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