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Eryavuz Onmaz Duygu Tezcan Dilek Abusoglu Sedat Sivrikaya Abdullah Kuzu Menekse Yerlikaya Fatma Humeyra Yilmaz Sema Unlu Ali 《Amino acids》2022,54(6):877-887
Amino Acids - Behçet disease (BD) is an inflammatory, multisystemic vasculitis of unknown etiopathogenesis. However, innate and adaptive immune system involvement and immune-mediated networks... 相似文献
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Dogan DG Dogan M Aslan M Menekse E Yakinci C 《Genetic counseling (Geneva, Switzerland)》2010,21(4):359-362
We report on a male infant with Hanhart Syndrome. It is classified in "oromandibular limb hypogenesis syndromes" which are a group of rare conditions involving congenital malformations of tongue, mandible, and limbs. 相似文献
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Wolfgang Grosse Philipp Reiß Simon Reitz Menekse Çebi Wolger Lübben Ulrich Koert Lars-Oliver Essen 《Bioorganic & medicinal chemistry》2010,18(22):7716-7723
Chemical modification of ion channels has recently attracted attention due to their potential use in stochastic sensing and neurobiology. Among the available channel templates stable β-barrel proteins have shown their potential for large scale chemical modifications due to their wide pore lumen. Ion-channel hybrids using the outer membrane protein OmpG were generated by S-alkylation with a synthetic modulator and functionally as well as structurally characterized. The dansyl moiety of the used modulator resulted in partial blockage of current though the OmpG channel with its gating characteristics mainly unaffected. The crystal structure of an OmpG–dansyl hybrid at 2.4 Å resolution correlates this finding by showing that the modulator lines the inner walling of the OmpG pore. These results underline the suitability of OmpG as a structural base for the construction of stochastic sensors. 相似文献
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