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The interaction of liposomes derived from total lipids of mouse spleen and liver with mouse spleen cells was studied. It was shown that the binding of these liposomes is much higher than the binding of liposomes obtained from a model lipid mixture--phosphatidylcholine--phosphatidylethanolamine--cholesterol (2:1:1). Adherent and nonadherent spleen cells were found to have affinity for liposomes derived from total lipids of spleen or liver. Removal of gangliosides and protein contaminants from the liposomes derived from total spleen lipids caused an increased binding of liposomes to spleen cells. Multilamellar liposomes bound more effectively to ultrasonicated vesicles having a homologous lipid composition than the liposomes with a different lipid composition. The increased affinity of liposomes derived from total lipids of spleen or liver for spleen cells may account for the identical fluidity of the lipid bilayer of liposomes and plasma membranes of spleen cells. 相似文献
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E I Mikliaeva M A Kulikov M E Ioffe 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1987,37(2):254-264
Preference was studied of one of the forelimbs during performance of different manipulating movements in white rats. High degree of "handedness" was observed in all studied movements. However it was not absolute--no animals performed all movements by one and the same limb. Degree and character of "handedness" were different for different movements, though the number of "righthanded" rats in most tests as a whole exceeded the number of "lefthanded" ones. The "handedness" depends on the individuality of the animal, the character of the motor task, learning and interference of different motor tasks during training. 相似文献
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The electroencephalographic and autonomic correlates of the mental reproduction of emotional states]
O A Sidorova M B Kostiunina M A Kulikov 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1991,41(5):891-898
The present study is devoted to the analysis of changes of bioelectrical and vegetative indices at mental reproduction of emotional states by man. Analysis is conducted of the data of mapping of intracortical interactions depending on the dynamics of R-R interval changes. Two stages of mental reproduction of emotions are revealed which are characterized by the presence of different centers of integration--in the frontal and temporal parts of the brain cortex. It is shown that at maximum emotional stress the integration center shifts from the frontal regions to the temporal region of the left hemisphere. 相似文献
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The influence of two mutations on the mate success of Drosophila melanogaster males was studied. Dominant temperature-sensitive lethal mutations l(2)M167DTS and l(2)M65DTS were used in experiments. Both these mutations are recessive lethals in homozygote. Individuals l(2)M65DTS and l(2)M167DTS die at 17 and 28 degrees C, respectively. The mate success of l(2)M65DTS males is much lower than that of normal males. In the experiments conducted in autumn, l(2)M167DTS males were always at advantage, whatever their age. In the winter experiments, they were only at advantage at the age of 2-3 and 15-17 days. For l(2)M167DTS males, a relationship has been established between the mate success and t degrees, and season. The role of behavioural pleiotropic effects of mutations on the probability of their fixation in a population is discussed. 相似文献
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